Game Changers Cancer Immunotherapies:

Checkpoint Inhibitors
September 2015

Precision Research & Consulting Pvt. Ltd.

www.idatainsights.com

Game Changers Cancer Immunotherapies:

Checkpoint Inhibitors

1.

Executive Summary

2.

Introduction
PD-1/PD-L1 Pathway
Role of PD-1/PD-L1 Pathway
Drugs Targeting the PD-1 vs. PD-L1 Pathway
Patterns and Evaluation of Response

Table of Content (Draft)

REPORT HIGHLIGHTS
How checkpoint inhibitors are revolutionizing treatment
options and expectations for cancer patients
An overview of global melanoma market
Case studies on Opdivo, Keytruda and Yervoy
Market potential of Opdivo and Keytruda

Safety
PD-L1 Inhibitors

A MUST BUY FOR

PD-1 Inhibitors
Rationale for Combination Therapies
PD-L1 as a Predictive Biomarker
Cytotoxic T-Lymphocyte Associated Antigen (CTLA-4)
Pathway

3.

Case Study 1: Opdivo (Bristol-Myers Squibb)

Product Profile

4.

5.

Professional from the pharmaceutical, biotech, medical device and

diagnostics industries with responsibilities or involvement in the
following areas:
Competitive Intelligence
Business Intelligence
Information Specialist

Development Timeline

Commercial/Customer Insights

Clinical Trial Profiles

Strategic Planning

Pricing Scenario

Market/Marketing Research

Regulatory Scenario

Decision Analysis/Decision Support

Life Cycle Management Activities

Business Analytics

Case Study 2: Keytruda (Merck)

New Product Planning/Development

Product Profile

Forecasting

Development Timeline

Librarian

Clinical Trial Profiles

Brand Management/Product Management

Pricing Scenario

Marketing

Regulatory Scenario

Business Portfolio Planning

Life Cycle Management Activities

Strategic/Business Analysis

Case Study 3: Yervoy (Bristol-Myers Squibb)

Business Development

Product Profile

Licensing

Development Timeline

Technical Analysis

Clinical Trial Profiles

Portfolio Management/Planning

Pricing Scenario

Project Management

Regulatory Scenario

Risk Management

Life Cycle Management Activities

Research Planning

Efficacy and Safety Comparison on Opdivo,

Keytruda and Yervoy in Melanoma

Regulatory

7.

Global Melanoma Market Overview

Scientist

8.

The PD-1 Wave: Opdivo and Keytruda Market Potential

9.

KOL Comments: Analysis of Statements from Various KOLs

6.

Precision Research & Consulting Pvt. Ltd.

Research & Development

Legal/Regulatory
Outsourcing
Manufacturing

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Game Changers Cancer Immunotherapies:

Checkpoint Inhibitors

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