EMILIO AGUINALDO COLLEGE

School of Nursing and Midwifery

1113-1117 San Marcelino St. Ermita Manila

Name of Drug
Generic Name: Biperiden

Classification
Pharmacologic Class:

Mechanism of Action
Therapeutic: Blocks

Indication
General Indication: As

Hydrochloride

Tertiary Amime

acetylcholines action at

adjunct to treat all forms of

cholinergic receptor sites. This

Parkinsons diseas. To control

Trade/Brand Name:

Therapeutic:

Akineton

Anticholinergic, Antidyskinetic

action restores the brains

EPSE (except tardive

Patients Dose: N/A

Pregnancy Risk Category:

normal dopamine and

dyskinesia) caused by

maximum: 16mg TID PO

pregnancy category C

acetylcholine balance, which

phenothiazines and other

minimum: 2mg TID or QID PO

relaxes muscle movement and

neuroleptic drugs.

Availability: Tablets, solution

decreases rigidity and tremors.

Patients Actual Indication:

May inhibit dopamine reuptake

N/A

for injection

Source:www.unilab.com

Route(s) of Administration:

and storage, which prolongs

PO, IM, IV

dopamines action

Source: nurseslabs.com

Pharmacokinetics:
Onset: IM-15 minutes ; IV10-30minutes
Peak: IM-unknown; IVunknown
Duration: IM=1-8hrs ;
IV=unknown
Drug Half-Life: 30hrs

1 |EAC

Drug Study Form

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Contraindication
Contraindication: Achalasia, bladder

Side Effects

Nursing Responsibilities
Before:

neck obstruction, hypersensitivity to

Blurred vision,

1. Monitor patients BP

biperiden, myasthenia gravis, narrow-

constipation,

2. Asses mental status

angle glaucoma, prostatic hypertrophy,

dysuria,

3. Assess muscle rigidity and tremor as

pyloric or duodenal obstruction, stenosing

muscle spasm,

baseline

peptic ulcer, toxic megacolon

decreased sweating

4. Assess fluid intake and bowel function

Drug Interactions: Drug-Drug

During:

amantadine: Possibly increased adverse

1. Administer oral dose with food, milk or

anticholinergic effects

water

Digoxin: Possibly increased serum digoxin

2. Expect to give IV or IM biperiden when

level

Adverse Effect
Agitation, confusion, delirium, delusions,

Haloperidol: Possibly increased

depression, disorientation, dizziness,

can provide

schizophrenic symptoms, decreased

drowsiness, euphoria, excitement, fever,

3. When giving biperiden to pt with drug

serum haloperidol level and development

hallucination, headache, light

induced Extrapyrimidal reaction, be alert

of tardive dyskinesia

headedness, memory loss, nervousness,

for worsening of psychiatric symptoms.

Levodopa: Possibly decreased levodopa

paranoia, psychosis, weakness

After:

effectiveness

pt needs more rapid response than drug

1. Dont let the pt sit or stand up until BP

and heart rate have returned to baseline
2. Caution pt to avoid driving and other
activities that requires alertness until

2 |EAC

Drug Study Form

lav-m2013

biperidens CNS effects are known

4. Instruct to frequently do good oral
hygiene
5. Be alert for and immediately report
signs of neuroleptic malignant syndrome
6. Emphasize the need for periodic eye
exam.

3 |EAC

Drug Study Form

lav-m2013