The document discusses the pathophysiology of hypertension. It describes how the kidneys release renin which triggers a chain reaction leading to increased blood volume and peripheral vascular resistance. Specifically, renin converts angiotensin I in the liver which is then converted to angiotensin II in the lungs, a vasoconstrictor. Angiotensin II also causes aldosterone release leading to sodium and water retention, increasing blood volume and blood pressure through arteriolar constriction and higher peripheral resistance.
The document discusses the pathophysiology of hypertension. It describes how the kidneys release renin which triggers a chain reaction leading to increased blood volume and peripheral vascular resistance. Specifically, renin converts angiotensin I in the liver which is then converted to angiotensin II in the lungs, a vasoconstrictor. Angiotensin II also causes aldosterone release leading to sodium and water retention, increasing blood volume and blood pressure through arteriolar constriction and higher peripheral resistance.
The document discusses the pathophysiology of hypertension. It describes how the kidneys release renin which triggers a chain reaction leading to increased blood volume and peripheral vascular resistance. Specifically, renin converts angiotensin I in the liver which is then converted to angiotensin II in the lungs, a vasoconstrictor. Angiotensin II also causes aldosterone release leading to sodium and water retention, increasing blood volume and blood pressure through arteriolar constriction and higher peripheral resistance.