Cerebral atrophy due to atherosclerosis of CA

Cerebral atrophy in Alzheimer's disease

Atrophy of brain and heart in aging (senile atrophy)
Although total cessation of oxygen perfusion results in cell death, partial
ischemia is often compatible with cell viability.
Atrophic kidney in renal artists. This resulted, however, in neuroanatomy
discrepancies,
inconsistencies, and even controversies among various communities in terms
of parcellation, demarcation, grouping, terminology, and presentation.
The present work differs from existing neuroanatomy primers. Our overall objectiveis
to make the presentation of brain anatomy easy. To achieve this objective:
The presentation of neuroanatomy is in three dimensions (3D) with additional
supportive planar images in the orthogonal (axial, coronal, and sagittal) planes.
The brain is subdivided inCerebral atrophy due to atherosclerosis of CA

Cerebral atrophy in Alzheimer's disease

Atrophy of brain and heart in aging (senile atrophy)
Although total cessation of oxygen perfusion results in cell death, partial
ischemia is often compatible with cell viability.
Atrophic kidney in renal to structure, vasculature, and connections (white matter
tracts); consequently, we consider structural, vascular, and connectional neuroanatomies.
W.L. Nowinski (*)
Biomedical Imaging Lab, ASTAR, Singapore
e-mail: wieslaw@sbic.a-star.edu.sg

Chapter 2

Introduction to Brain Anatomy

Wieslaw L. Nowinski
6 W.L. Nowinski

3D cerebral models of structure, vasculature, and tracts are mutually consistent

because they were derived from the same brain specimen.
3D cerebral models and the planar images are fully parcellated; each parcellated
object is uniquely colored.
3D cerebral models and the planar images are completely labeled; as a terminology,we
use the Terminologia Anatomica [75].
3D cerebral models are electronically dissectible into groups and individual
components.
In this work, we use the digital brain atlases developed in our laboratory for
nearly 2 decades [6369]. The 3D cerebral models have been created from multiple
3 and 7 Tesla magnetic resonance scans of the same brain specimen (WLN) [69].
The development of the atlases is addressed in [7680], tools for their development
in [81], techniques for modeling of cerebral structures in [76, 82, 83], and atlasbased
applications in [7780, 8492].

2.2 Structural (Gross) Neuroanatomy

We present parcellation of the brain in 3D followed by sectional neuroanatomy. The
stereotactic target structures and functional (Brodmanns) areas also are outlined.

2.2.1 Brain Parcellation

The CNS consists of the brain and the spinal cord. The brain encases the fluid-filled
ventricular system and is parcellated into three main components (Fig. 2.1a):
Cerebrum
Cerebellum (the little brain)
Brainstem
The cerebrum comprises:
Left and right cerebral hemispheres
Interbrain between the cerebrum and the brainstem termed the diencephalon
Deep gray nuclei
The cerebral hemispheres are the largest compartment of the brain and are interconnected
by white matter fibers (see Sect. 2.4.2). The hemispheres are composed of:
Outer gray matter termed the cerebral cortex
Inner white matter encompassing the deep gray nuclei
2 Introduction to Brain Anatomy 7

Fig. 2.1 Gross anatomy of the left cCerebral

atrophy due to atherosclerosis of CA

Cerebral atrophy in Alzheimer's disease
Atrophy of brain and heart in aging (senile atrophy)
Although total cessation of oxygen perfusion results in cell death, partial
ischemia is often compatible with cell viability.
Atrophic kidney in renal erebral hemisphere: (a) brain parcellation; (b) lobes: la