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Quizlet Pharma Exam 1
Quizlet Pharma Exam 1
Quizlet Pharma Exam 1
a1
receptor
12.
Alpha
receptors
2.
a2
receptor
13.
Altered
absorption
3.
aa
of each
4.
ACh
14.
Altered
excretion
5.
AC PC
6.
active
transport
Altered
metabolism
Additive
effects
16.
anabolic
8.
Adjusted
Body
Weight
equation
17.
Antagonism
9.
Adverse
Drug
Events
18.
ATC
19.
B1 receptor
Adverse
Drug
Reaction
20.
B2
receptors
Agonists
21.
best pass
through
plasma
membranes
22.
Beta
Receptors
23.
BID
7.
10.
11.
24.
carrier
assisted
diffusion
25.
catabolic
26.
categories of
pregnancy
risk factors
A: no risk to fetus
B: no risk in animal studies but no human
studies or animal studies are bad but
human studies are fine
C: adverse animal studies and no controlled
studies for women or studies in women and
animals are not available. weigh risks v
benefits
D: positive evidence of human fetal risk but
benefits are worth it (life threatening
situation)
X: risk in pregnant women totally outweighs
any benefit. kids and animals are deformed.
drug is totally contradicted
27.
CC
with meals
28.
Chelation
29.
Clinically
significant
drug
interactions
30.
Clinical
Pharmacology
Competition
for serum
protein
binding
31.
competitve
antagonism
33.
continuous
infusion
34.
Creatinine
clearance
calculation
35.
CYP3A4
Inducers
carbamazepine
phenobarbital
phenytoin
rifampin
increase metabolic rate, serum drug levels
decrease
36.
CYP3A4
Inhibitors
ketoconazole
erthyromycin
grapefruit juice
ritonavir
decrease metabolic rate, drug level increases
37.
CYP3A4
Substrates
nifedipine
erythromycin
midazolam
testosterone
38.
CYP
enzymes are
involved in
the
metabolism
of what
percentage
of drugs
39.
CYP
Induction
40.
CYP
inhibition
41.
cytochrome
P450
42.
DC
discontinue
54.
43.
Diagnostic
drugs
Drug
distribution
55.
drug efficacy
56.
drug factors
that affect
absorption
through
tissues and
membranes
57.
drug
formulation
depends on:
58.
drug
idiosyncracy
59.
drug
monograph
60.
drug potency
61.
Drug stability
62.
Duration of
action
63.
effective
concentration
44.
Dissociation
constant (Kd)
45.
Distribution
half life
46.
Do not
abbreviate
47.
dopamine
48.
dopaminergic
receptors
49.
Drug
50.
Drug
absorption
51.
Drug
absorption
for topical
ophthalmic
medications
drug binding
to receptor
sites causes
52.
53.
drug
deposition
64.
Elimination half
life
65.
66.
67.
gtt
drop
68.
half life
69.
H.S.
at bedtime
70.
hydrophillic
channels
71.
hypoalbuminemia
72.
73.
IH
74.
IM
75.
include on a
prescription
76.
INJ
inject
77.
intermittent
dose
78.
Intradermal
79.
irreversible
antagonism
80.
Isoenzymes
responsible
for P450
catalyzed
reactions
81.
IV
82.
Lbs to Kg
2.2lb/kg
83.
lethal dose
84.
Liver
function
tests
85.
Loading
dose
86.
maitenance
doses
87.
88.
89.
90.
major modes of
drug excretion
margin of safety
Medication Error
Medication Errors
91.
medication
history list
92.
Microsomal
(membrane
bound)OXIDATION
phase 1
hydroxylation
dealkylation
oxidation
polarizing atom exchange
93.
Microsomal
Membrane bound
REDUCTION
azoreduction
nitroreduction
94.
95.
Most rapid
onset/most
bioavailability
intravenous, intramuscular,
subcutaneous, oral, rectal, inhalation,
transdermal
96.
non competitve
antagonism
97.
Non microsomal
oxidation and
reduction
98.
Norepinephrine
99.
P450 inducer
100.
P450 inhibitor
101.
Parasympathetic
- cranial sacral
102.
Parasympathetic
transmission
103.
Parenteral
104.
passive diffusion
105.
Pharmacodynamics
106.
Pharmacogenetics
107.
Pharmacogenomics
108.
Pharmacokinetics
(ADME)
109.
Pharmacology
110.
Pharmacotherapeutics
111.
112.
113.
Phase 2 reactions
Phases of drug
metabolism
Physiologic Drug
Dependence
glucuronide conjugation
ethereal sulfate conjugation
acetylation
transulfuration
glutathione conjugation
116.
PO
117.
Potentiation
118.
PR
119.
Prevention of
absorption
120.
PRN
as needed
121.
prodrug
114.
115.
pH + log (HA)/A
pH<pKa for a weak acid, the
uncharged protonated form
predominates
enalapril
procainamide
napafenac
122.
Prophylactic
drugs
123.
Psychological
dependence
124.
every
125.
qDay
once a day
126.
QID
127.
QOD
128.
qs
up to
129.
referral plan
130.
renal excretion
131.
sig
132.
ss
one half
133.
steady state
134.
subcutaenous
135.
Sublingual
136.
Substrates
137.
Sympathetic thoracolumbar
138.
Syngerism
139.
therapeutic
effect
140.
therapeutic
index
141.
TID
142.
tolerance
143.
Topical
144.
Transdermal
145.
Treatment
drugs
146.
Type A
Reactions
147.
Type B
Reactions
148.
UD
as directed
149.
Ung
ointment
150.
WA
while awake
151.
When to use
adjusted
body weight