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Plumbago Zeylanica: A Phytopharmacological Review
Plumbago Zeylanica: A Phytopharmacological Review
2 (2): 247-255
IJPSR (2011), Vol. 2, Issue 2
ISSN: 0975-8232
(Review Article)
Received on 19 September, 2010; received in revised form 18 November, 2010; accepted 17 January, 2011
Correspondence to Author:
Dr Vishnukanta
Department of Pharmacology, B. N.
(PG) College of Pharmacy, Udaipur,
Rajasthan India
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Two plumbagic acid glucosides; 3o-betaglucopyranosyl plumbagic acid and 3-o-betaglucopyranosyl plumbagic acid methyl ester along
with five naphthaquinones (plumbagin, chitranone,
maritinone, elliptinone and isoshinanolone), and
five
coumarins
(seselin,
methoxyseselin,
suberosine, xanthyletin and xanthoxyletin) were
isolated from the roots 5.
Fruit: It contains plumbagin, glucopyranoside, and
sitosterol.
Seeds: Seeds contain plumbagin.
Pharmacology and traditional uses:
Flower: Digestent 1.
Leaves: Leaves are caustic, vesicant, aphrodisiac,
good for scabies, stimulant, and also use in sore
and swelling 6. They are used to treat infections
and digestive problems such as dysentery.
Externally a paste is applied to painful rheumatic
areas or to chronic and itchy skin problems 7.
Stem: The ethanolic stem extract inhibited the
growth of Leishmania amazonensis promastigotes
by 88% at 100 g/ml 1.
Roots: root is bitter, laxative, expectorant, tonic,
abortifacient,
good
appetizer,
useful
in
rheumatism, laryngitis, scabies and disease of
spleen 6.
Root powder showed presence of protease
enzyme, trace quantity of Vit. A, B1, B2, and C and
was found to be GIT flora normalizer. It stimulates
the proliferation of coliform bacteria in mice. It is
abortifacient and has vesicant properties. The
tincture of the root bark is a powerful sudorifice
and antiperiodic. It irritates the uterus, enhances
its contractions, and hence is useful in cleansing it.
It is absolutely contraindicated in pregnancy 2. In
the form of an external paste; root is used in
filariasis, depigmentation of the skin and anasarca
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