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Syllabus BIO1820 Spring 2015
Syllabus BIO1820 Spring 2015
BIO1820
Overview
In this course you will have the opportunity to explore
environmental health issues, scientific understanding of causes,
and possible future approaches to the major environmental
health problems in industrialized and developing countries.
Topics include how the human body reacts to environmental
pollutants; dose responses to different environmental toxicants;
the absorption, metabolism and excretion of toxicants in living
organisms; mechanisms of toxicity of selected environmental
toxicants and their effects on human organ systems; biomarkers
and risk analysis; and emerging global environmental health
problems.
This course also explores the relationship of humans to the
environmenthow it affects our well being, what we can do to
protect and enhance our health, and how we can influence the
quality of the environment.
Goals
This course has three specific goals:
1. To identify the principles and mechanisms governing the
interactions of environmental toxicants with living
organisms.
Course Materials
Essentials of Environmental Health.
Robert H. Friis, 2nd edition, 2012, by
Jones & Bartlett Learning, LLC,
ISBN-978-0-7637-7890-3
A textbook of Modern Toxicology.
Ernest Hodgson, 4th edition, 2010, by
John Wiley & Sons Inc., ISBN-9780470462065 (e-version at SL)
(there is no required textbook)
Milestones
02/13/15
Exam I. Lectures: 01/23-02/11/15
03/13/15
Exam II. Lectures: 02/2003/13/15
04/10/15
Exam III. Lectures: 03/1804/08/15
04/20-04/24/15
Research paper presentation.
Objectives
Upon successful completion of this course, you will be able to:
1. Define the major sources and types of environmental toxicants.
2. Discuss the transport and fate of these toxicants in the environment and human body.
3. Understand how environmental toxicants interact with biological systems, and the mechanisms by
which they exert adverse effects on human health.
4. Know which diseases are associated with environmental exposures to toxic substances.
5. To take an action to minimize your exposure to the environmental toxicants and create a healthier
living environment.
General Policies
You will promote your efficient learning and ensure deep understanding of course material if you read
the required readings materials before the lecture and contribute informed opinions about the material
during class discussions. I am interested in what you think about what you have read. Participation in
class discussions is highly encouraged.
Required readings are listed in the Course Outline section of the syllabus. The scientific papers will be
available for you on the Canvas course website.
Grading Policies
The course grade will be based on 3 exams, scientific paper and research paper presentations.
Exam 1
Scientific paper presentation
Exam 2
Exam 3
Research paper presentation
25%
15%
25%
25%
10%
Grading Scale
Your final grade will be based on the following scale:
A = 90-100%
B = 80-89%
C = 70-79%
Exams
There will be three exams during the course. The exams will be based on the lecture content, required
reading materials and any additional information (handouts, articles, etc.) posted on the course website.
The exam questions will consist of multiple choice and short answer questions.
Introduction: when, where, what kind, and how the release of toxicants happened.
What were the impacts on human health?
What were the scientific follow-up studies on the hazardous event?
What remediation/possible ways to clean it up were attempted?
Were any changes made to the environmental laws?
What are your reflections on the researched environmental health issue?
Academic Honesty
Brown University has an Academic Code that defines academic dishonesty, and the policies and
penalties governing violations. Please, visit the following website for more information:
http://www.brown.edu/administration/Dean_of_the_College/curriculum/documents/principles.pdf
Disability Accommodations
Students requiring a disability-related accommodations should contact me directly at the beginning of
the semester, as well as the Office of Student & Employee Accessibility Services for arrangements they
may require: http://brown.edu/ seas
Course Outline
Date
Lecture
Required Readings
01/26/15 Introduction to
environmental
toxicology: the link
between
environmental
exposure and health.
01/28/15 The general health
effects of air
pollution.
http://www.nytimes.com/2013/02/24/us/utah-a-nature-lovers-haven-isplagued-by-dirty-air.html?hp&_r=0
http://www.nytimes.com/2014/12/01/us/west-virginia-coal-countrysees-new-era-as-a-mine-boss-isindicted.html?hp&action=click&pgtype=Homepage&module=secondcolumn-region®ion=top-news&WT.nav=top-news
http://www.nytimes.com/interactive/2014/11/23/us/north-dakota-oilboom-downside.html?emc=eta1&_r=0
02/06/15 Student
presentations.
02/11/15 Student
presentations.
02/13/15 Exam I
02/16/15 No class.
02/18/15 Principles of
toxicology.
02/20/15 Absorption,
distribution and
excretion of
toxicants.
02/23/15 Mechanisms of
toxicity: cellular
dysfunction and
resultant toxicities.
02/25/15 Student
presentations.
03/04/15 Student
presentations.
http://www.brown.edu/Research/SRP/
www.niehs.nih.gov/srp
03/11/15 Student
presentations.
03/18/15 Student
presentations.
http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products
/Guidelines/Multidisciplinary/M3_R2/Step4/M3_R2__Guideline.pdf
http://www.ema.europa.eu/docs/en_GB/document_library/
Scientific_guideline/2009/10/WC500003978.pdf
04/01/15 Environmental
contaminants and
childrens health.
Autism.
04/03/15 Student
presentations.
04/08/15 Student
presentations.
04/15/15 Student
presentations.
04/17/15 Love canal and the
birth of
environmental
movement.