List of Rare Cancers

Rare cancers are those with an incidence rate 6/100,000
Layer
Tumour
1 EPITHELIAL TUMOURS OF THE NASAL CAVITY and SINUSES
2 Squamous cell carcinoma and variants of the Nasal Cavity and Sinuses
3
Squamous carcinoma
3
Verrucous carcinoma
3
Squamous cell carcinoma spindle cell
3
Papillary squamous cell carcinoma
3
Basaloid carcinoma
3
Adenosquamous carcinoma
3
Squamous cell carcinoma, adenoid
3
Basaloid squamous cell carcinoma
3
Spindle cell carcinoma
2 Lymphoepithelial carcinoma of the Nasal Cavity and Sinuses
2 Undifferentiated carcinoma of the Nasal Cavity and Sinuses
2 Intestinal type adenocarcinoma the Nasal Cavity and Sinuses
1 EPITHELIAL TUMOURS OF THE NASOPHARYNX
2 Squamous cell carcinoma and variants of the Nasopharynx
3
Squamous carcinoma
3
Squamous cell carcinoma non keratinizing, NOS
3
Squamous cell carcinoma keratinizing, NOS
3
3
3
3
Lymphoepithelial carcinoma
3
Undifferentiated carcinoma
2 Papillary adenocarcinoma of the Nasopharynx
1 EPITHELIAL TUMOURS OF THE MAJOR SALIVARY GLANDS and SALIVARY-GLAND TYPE TUMOURS
Rate x 100,000
0.44
0.31
0.24
0.01
0.00
0.00
0.00
0.00
0.00
NE
NE
0.00
0.02
0.00
0.45
0.33
0.112
0.001
0.016
0.001
NE
0.00
0.057
0.064
0.00
1.31
Patients
3,594
2,515
1,708
35
6
8
10
13
3
0
0
20
142
20
3,618
2,657
1,156
144
111
7
0
1
405
457
7
10,633
2
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
3
3
3
3
3
3
3
3
3
3
3
3
Epithelial tumours of the major salivary glands

Squamous carcinoma
Large cell carcinoma
Carcinosarcoma, NOS
Adenocarcinoma NOS
Clear cell adenocarcinoma, NOS
Mucinous adenocarcinoma
Ductal carcinoma
Oxyphilic adenocarcinoma
Papillary cystadenocarcinoma, NOS
Adenoid cystic carcinoma
Mucoepidermoid carcinoma
Acinic cell adenocarcinoma
Malignant myoepithelioma
Carcinoma in pleomorphic adenoma
Polymorphous low grade adenocarcinoma
Basal cell adenocarcinoma
Epithelial-myoepithelial carcinoma
Sebaceous adenocarcinoma
Cystadenocarcinoma, NOS
Low grade cribriform cystadenocarcinoma
Salivary gland type tumours of the Head and Neck
Adenocarcinoma NOS
Ductal carcinoma
Epithelial-myoepithelial carcinoma
Polymorphous low grade adenocarcinoma
Carcinoma in pleomorphic adenoma
Malignant myoepithelioma
0.73
0.119
0.005
0.003
0.001
0.138
0.003
0.003
0.011
0.004
0.001
0.115
0.114
0.089
0.001
0.019
0.00
0.006
0.017
NE
NE
NE
0.43
0.05
0.046
0.041
0.006
NE
0.002
0.002
0.002
0.001
0.001
0.001
NE
5,919
851
34
18
9
988
18
22
80
27
4
825
815
638
10
136
2
42
121
0
0
0
3,492
354
327
296
40
0
12
12
11
9
5
5
0
3
Cystadenocarcinoma, NOS
3
Oncocytic carcinoma
3
Myoepithelial carcinoma
3
Papillary cystadenocarcinoma, NOS
1 EPITHELIAL TUMOURS OF THE HYPOPHARYNX AND LARYNX
2 Squamous cell carcinoma and variants of the Hypopharynx
3
Squamous carcinoma
3
3
Verrucous carcinoma
3
3
Giant cell carcinoma
3
Basaloid carcinoma
3
3
3
3
3
2 Squamous cell carcinoma and variants of the Larynx
3
Squamous carcinoma
3
Verrucous carcinoma
3
3
3
3
Basaloid carcinoma
3
3
3
3
3
1 EPITHELIAL TUMOURS OF THE OROPHARYNX
2 Squamous cell carcinoma and variants of the Oropharynx
3
Squamous carcinoma
3
3
Verrucous carcinoma
3
NE
0.00
NE
NE
6.29
1.19
0.415
0.001
0.001
0.001
NE
0.001
0.001
0.00
0.006
0.001
NE
4.67
3.597
0.048
0.01
0.006
0.006
0.004
0.001
0.012
0.001
NE
0.001
2.75
2.59
1.812
0.009
0.006
0.003
0
3
0
0
51,000
9,633
2,967
10
5
6
0
8
8
2
40
4
0
37,851
25,720
344
71
42
42
26
8
83
8
0
5
22,337
21,012
12,958
61
46
19
3
3
Basaloid carcinoma
3
3
3
3
1 EPITHELIAL TUMOURS OF THE ORAL CAVITY and LIP
2 Squamous cell carcinoma and variants of the Oral cavity
3
Squamous carcinoma
3
Verrucous carcinoma
3
3
3
3
Basaloid carcinoma
3
3
3
3
2 Squamous cell carcinoma and variants of the Lip
3
Squamous carcinoma
1 EPITHELIAL TUMOURS OF THE OESOPHAGUS
2 Squamous cell carcinoma and variants of the Oesophagus
3
Squamous carcinoma
3
3
3
Basaloid carcinoma
3
Verrucous carcinoma
3
3
3
2 Adenocarcinoma and variants of the Oesophagus
2 Salivary gland type tumours of the Oesophagus
3
3
0.003
0.002
0.001
0.001
0.004
0.013
4.8
3.3
2.487
0.057
0.004
0.004
NE
0.002
0.001
0.001
0.001
0.013
1.22
1.212
7.49
3.39
2.802
0.038
0.004
0.004
0.002
0.001
0.001
0.001
2.83
0.01
0.003
0.001
22
17
5
8
31
91
38,892
26,720
17,784
411
32
28
0
17
6
6
5
93
9,894
8,667
60,723
27,525
20,038
270
31
30
13
6
6
5
22,986
47
18
7
2 Undifferentiated carcinoma of the Oesophagus

1 EPITHELIAL TUMOURS OF THE STOMACH
2 Adenocarcinoma and variants of the Stomach
3
Adenocarcinoma, NOS
3
Adenocarcinoma intestinal type
3
Signet ring cell carcinoma
3
Carcinoma diffuse type
3
3
Tubular adenocarcinoma
3
Papillary adenocarcinoma, NOS
3
2 Squamous cell carcinoma and variants of the Stomach
3
Squamous carcinoma
3
3
Basaloid carcinoma
3
Verrucous carcinoma
3
3
2 Salivary gland type tumours of the Stomach
3
3
2 Undifferentiated carcinoma of the Stomach
1 EPITHELIAL TUMOURS OF THE SMALL INTESTINE
2 Adenocarcinoma and variants of the Small Intestine
3
Adenocarcinoma, NOS
3
3
3
3
Medullary carcinoma, NOS
3
2 Squamous cell carcinoma and variants of the Small Intestine
3
Squamous carcinoma
1 EPITHELIAL TUMOURS OF THE COLON
2 Adenocarcinoma and variants of the Colon
0.07
18.66
15.27
9.366
1.743
1.612
0.754
0.611
0.31
0.071
0.024
0.13
0.102
0.00
0.00
0.00
0.00
NE
0.01
0.002
0.002
0.17
0.73
0.57
0.47
0.04
0.01
0.001
NE
0.11
0.01
0.001
42.78
37.36
595
151,346
123,800
72,580
13,503
12,494
5,843
4,735
2,399
549
186
1,049
788
1
1
1
1
0
41
13
12
1,361
5,882
4,615
3
281
72
6
0
77
51
14
346,910
302,918
3
Adenocarcinoma NOS
3
3
3
3
3
2 Squamous cell carcinoma and variants of the Colon
1 EPITHELIAL TUMOURS OF THE RECTUM
2 Adenocarcinoma and variants of the Rectum
25.828
2.843
0.185
0.015
0.064
0.00
0.02
17.12
15.52
200,140
22,033
1,436
114
456
2
170
138,806
125,890
3
Adenocarcinoma NOS
3
3
3
3
3
2 Squamous cell carcinoma and variants of the Rectum
3
Verrucous carcinoma
2 Basaloid carcinoma of the Rectum
1 EPITHELIAL TUMOURS OF THE ANAL CANAL
2 Squamous cell carcinoma and variants of the Anal Canal
3
Verrucous carcinoma
3
2 Adenocarcinoma and variants of the Anal Canal
3
2 Basaloid carcinoma of the Anal Canal
2 Paget disease of the Anal Canal
1 EPITHELIAL TUMOURS OF THE PANCREAS
2 Adenocarcinoma and variants of the Pancreas
3
Adenocarcinoma NOS
3
3
3
3
2 Squamous cell carcinoma and variants of the Pancreas
15.108
0.958
0.066
0.009
0.017
0.00
0.07
0.001
0.02
1.1
0.61
0.009
0.005
0.26
0.022
0.12
0.00
11.82
7.58
4.03
0.27
0.071
0.023
0.021
0.03
117,075
7,428
511
66
125
1
600
4
123
8,922
4,982
62
35
2,098
157
993
32
95,836
61,459
28,815
1,932
510
162
150
211
2 Acinar cell carcinoma of the Pancreas

2 Mucinous cystadenocarcinoma of the Pancreas
2 Intraductal papillary mucinous carcinoma invasive of the Pancreas
2 Solid pseudopapillary carcinoma of the Pancreas
2 Serous cystadenocarcinoma of the Pancreas
2 Carcinoma with osteoclast-like giant cells of the Pancreas
1 EPITHELIAL TUMOURS OF THE LIVER and INTRAEPATIC BILE TRACT (IBT)
2 Hepatocellular carcinoma of the Liver and IBT
3
Combined hepatocellular carcinoma and cholangiocarcinoma
3
Hepatocellular carcinoma, fibrolamellar
2 Cholangiocarcinoma of the IBT
2 Adenocarcinoma and variants of the Liver and IBT
2 Undifferentiated carcinoma of the Liver and IBT
2 Squamous cell carcinoma and variants of the Liver and IBT
2 Bile duct cystadenocarcinoma of the IBT
1 EPITHELIAL TUMOURS OF THE GALLBLADDER and EXTRAHEPATIC BILIARY TRACT (EBT)
2 Adenocarcinoma and variants of the Gallbladder and EBT
3
Cholangiocarcinoma
3
3
3
3
3
3
3
3
Bile duct cystadenocarcinoma
2 Combined hepatocellular carcinoma and cholangiocarcinoma of the Gallbladder and EBT
2 Squamous cell carcinoma of the Gallbladder and EBT
1 EPITHELIAL TUMOUR OF THE TRACHEA
2 Squamous cell carcinoma and variants of the Trachea
3
Squamous carcinoma
3
3
3
Squamous cell carcinoma clear cell type
0.02
0.01
0.00
0.00
0.00
NE
6.28
3.1
0.046
0.009
0.83
0.21
0.02
0.01
0.00
4.42
2.64
0.083
0.075
0.003
0.092
0.003
0.022
0.034
0.039
0.00
0.00
0.04
0.13
0.08
0.064
0.00
NE
NE
175
65
5
6
1
0
50,933
25,123
327
61
6,761
1,688
131
92
14
35,840
21,403
643
539
24
657
23
156
240
281
2
14
293
1,090
663
459
2
0
0
3
Verrucous carcinoma
3
3
3
3
3
3
2 Adenocarcinoma and variants of the Trachea
3
Adenocarcinoma NOS
3
3
3
Solid carcinoma, NOS
3
3
3
3
Mucinous cystadenocarcinoma, NOS
2 Salivary gland type tumours of the Trachea
3
3
3
1 EPITHELIAL TUMOUR OF THE LUNG
2 Squamous cell carcinoma and variants of the Lung
3
Squamous carcinoma
3
3
3
Squamous cell carcinoma small cell non keratinizing
3
Squamous cell carcinoma clear cell type
2 Adenocarcinoma and variants of the Lung
3
Adenocarcinoma NOS
3
3
3
3
3
3
NE
NE
0.00
0.001
NE
NE
0.002
0.01
0.012
0.00
0.00
0.001
0.00
NE
NE
NE
0.01
0.009
0.001
0.00
56.1
13.5
12.798
0.005
0.001
0.026
0.00
10.33
9.363
0.108
0.137
0.024
0.053
0.047
0.02
0
0
2
5
0
0
16
108
87
3
1
4
1
0
0
0
79
64
6
1
454,883
109,474
91,514
37
9
184
1
83,764
66,947
773
980
174
378
337
145
3
3
3
Adenocarcinoma with mixed subtypes
3
Fetal adenocarcinoma
2 Large cell carcinoma of the Lung
2 Well diff endocrine carc of the lung
2 Poorly differentiated endocrine carcinoma of the Lung
3
Small cell endocrine carcinoma of the Lung
3
Large cell endocrine carcinoma of the Lung
2 Bronchiolo-alveolar carcinoma of the Lung
3
Bronchiolo-alveolar carcinoma, mucinous
3
Bronchiolo-alveolar carcinoma, non mucinous
3
Bronchiolo-alveolar carcinoma, mixed mucinous and non-mucinous
2 Salivary gland type tumours of the Lung
3
3
3
2 Sarcomatoid carcinoma of the Lung
3
Sarcomatoid carcinoma
3
Pleomorphic carcinoma
3
3
Carcinosarcoma, NOS
3
2 Undifferentiated carcinoma of the Lung
1 EPITHELIAL TUMOURS OF THE THYMUS
2 Malignant tymoma
3
Thymoma, malignant, NOS
3
Malignant thymoma, type AB
3
Malignant thymoma, type A
3
Malignant thymoma, type B
3
Malignant thymoma, type C
2 Squamous cell carcinoma of the Thymus
2 Undifferentiated carcinoma of the Thymus
2 Lymphoepithelial carcinoma of the Thymus
0.283
0.00
0.00
NE
4.01
0.63
7.68
7.485
2.357
0.69
0.002
0.001
0.001
0.04
0.016
0.024
0.00
0.14
0.018
0.032
0.034
0.023
0.02
0.98
0.17
0.14
0.123
0.001
0.00
0.002
0.002
0.00
0.00
0.00
2
2
1
0
32,526
5,121
62,293
53,513
16,856
5,566
11
9
4
358
117
174
2
1,137
124
226
245
168
145
7,951
1,364
1,119
880
8
1
16
11
38
20
6
2 Adenocarcinoma and variants of the Thymus

3
Adenocarcinoma NOS
3
1 EPITHELIAL TUMOURS OF THE BREAST
2 Invasive ductal carcinoma of the Breast
2 Invasive lobular carcinoma of the Breast
3
Classic type
3
2 Mammary Pagets disease of the Breast
2 Special types of adenocarcinoma of the Breast
3
3
Mucinous carcinoma
3
3
3
Cribriform carcinoma
3
Apocrine adenocarcinoma
3
Secretory carcinoma
3
Glycogen-rich clear cell carcinoma
3
Lipid-rich carcinoma
3
Oncocytic carcinoma
2 Metaplastic carcinoma of the Breast
3
Squamous carcinoma
3
3
Adenocarcinoma with cartilaginous and osseous metaplasia
3
Adenocarcinoma with spindle cell metaplasia
2 Salivary gland type tumours of the Breast
3
3
3
3
2 Epithelial tumour of the Male Breast
1 EPITHELIAL TUMOURS OF THE CORPUS UTERI
2 Adenocarcinoma and variants of the Corpus Uteri
3
Adenocarcinoma NOS
0.00
0.001
0.00
64.03
40.43
7.24
6.744
0.018
0.51
3.58
1.35
1.186
0.464
0.384
0.162
0.061
0.005
0.002
0.001
0.00
0.06
0.039
0.009
0.006
0.005
0.05
0.002
0.033
0.005
0.014
0.97
10.42
9.54
5.154
16
6
2
519,188
327,855
58,726
52,261
138
4,135
28,997
10,463
9,188
3,597
2,979
1,253
470
41
14
7
1
495
299
73
43
37
426
16
252
38
112
3,835
84,500
77,394
39,939
10
3
Endometrioid adenocarcinoma, NOS
3
3
3
Serous cystadenocarcinoma, NOS
3
3
Mixed cell adenocarcinoma
3
Endometrioid adenocarcinoma secretory variant
3
Villous adenocarcinoma
3
Endometrioid adenocarcinoma ciliated cell variant
2 Squamous cell carcinoma and variants of the Corpus Uteri
2 Adenoid cystic carcinoma of the Corpus Uteri
2 Transitional cell carcinoma of the Corpus Uteri
1 EPITHELIAL TUMOURS OF THE CERVIX UTERI
2 Squamous cell carcinoma and variants of the Cervix Uteri
3
Squamous carcinoma
3
Squamous cell carcinoma non keratinizing, NOS
3
Squamous cell carcinoma keratinizing, NOS
3
3
Papillary carcinoma, NOS
3
Verrucous/Warty carcinoma
3
Basaloid carcinoma
3
3
3
Transitional cell carcinoma, NOS
3
Glassy cell carcinoma
2 Adenocarcinoma and variants of the Cervix Uteri
3
Adenocarcinoma NOS
3
Adenocarcinoma with squamous metaplasia
3
3
3
3
3
3
Mesonephroma malignant
3
Villous adenocarcinoma
2.464
0.337
0.122
0.099
0.075
0.004
0.002
0.002
0.00
0.12
0.00
0.00
6.07
4.28
2.71
0.369
0.367
0.009
0.003
0.003
0.003
0.002
0.001
0.001
0.00
1.01
0.618
0.154
0.036
0.025
0.019
0.004
0.002
0.002
0.001
19,095
2,614
944
768
580
34
15
16
1
945
11
1
49,259
34,703
20,997
2,862
2,846
68
26
25
23
12
9
9
1
8,198
4,791
1,191
272
197
147
28
13
16
8
11
3
Mucinous adenocarcinoma, endocervical type
3
3
Mixed cell adenocarcinoma
2 Undifferentiated carcinoma of the Cervix Uteri
1 MIXED EPITHELIAL AND MESENCHYMAL TUMOURS OF THE UTERUS
2 Mixed epithelial and mesenchymal tumours of the uterus
1 EPITHELIAL TUMOURS OF THE OVARY and OF THE FALLOPIAN TUBE
2 Adenocarcinoma and variants of the Ovary
3
3
Adenocarcinoma NOS
3
3
3
Serous surface papillary carcinoma
3
Endometrioid adenofibroma malignant
3
Clear cell adenocarcinofibroma
3
Serous adenocarcinofibroma
3
Mucinous adenocarcinofibroma
2 Mucinous adenocarcinoma of the Ovary
2 Clear cell adenocarcinomaof the Ovary
2 Adenocarcinoma and variants of the Fallopian Tube
3
Adenocarcinoma NOS
3
Papillary serous cystadenocarcinoma
3
3
1 NON EPITHELIAL TUMOURS OF THE OVARY
2 Mixed epithelial/mesenchymal tumours of the Ovary
3
Mullerian mixed tumour
3
Adenosarcoma
2 Sex cord tumours of the Ovary
3
Granulosa cell tumour malignant
3
Sertoli-Leydig cell tumour poorly differentiated
3
Steroid cell tumour, malignant
2 Malignant/Immature Teratomas of the Ovary
3
Teratoma, malignant, NOS
0.00
0.00
0.00
0.03
0.45
0.45
9.41
5.97
2.539
1.435
0.812
0.322
0.111
0.017
0.001
0.001
0.00
0.84
0.32
0.27
0.078
0.029
0.014
0.021
0.43
0.16
0.149
0.001
0.13
0.108
0.002
0.00
0.07
0.049
2
3
3
203
3,613
3,613
76,284
48,410
19,681
11,122
6,294
2,502
863
133
6
8
1
6,852
2,622
2,168
558
204
102
147
3,513
1,270
1,154
6
1,088
840
17
1
548
379
12
3
Struma ovarii, malignant
3
Primitive neuroectodermal tumour, NOS
3
Ependymoma
3
Medulloepithelioma, NOS
3
Glioblastoma
3
2 Germ cell tumour of the Ovary
3
Dysgerminoma/Seminoma
3
Yolk sac tumour
3
Mixed germ cell tumour
3
Embryonal adenocarcinoma
3
Choriocarcinoma, NOS
3
Polyembryoma
1 EPITHELIAL TUMOURS OF THE VULVA & VAGINA
2 Squamous cell carcinoma and variants of the Vulva and Vagina
2 Adenocarcinoma and variants of the Vulva and Vagina
2 Paget disease of the Vulva and Vagina
2 Undifferentiated carcinoma of the Vulva and Vagina
1 TROPHOBLASTIC TUMOUR OF THE PLACENTA
2 Choriocarcinoma of the Placenta
1 EPITELIAL TUMOURS OF THE PROSTATE
2 Adenocarcinoma and variants of the Prostate
3
Adenocarcinoma NOS
3
3
3
3
Adenocarcinoma with neuroendocrine differentiation
3
Oxyphilic adenocarcinoma
3
3
2 Squamous cell carcinoma and variants of the Prostate
3
Squamous carcinoma
3
2 Infiltrating duct carcinoma of the Prostate
0.002
0.00
NE
NE
NE
NE
0.07
0.035
0.021
0.004
0.003
0.002
0.001
1.91
1.5
0.08
0.05
0.01
0.02
0.02
47.94
40.57
36.955
0.464
0.025
0.01
0.00
0.00
NE
NE
0.11
0.015
0.001
0.47
17
1
0
0
0
0
607
269
159
32
24
14
4
15,522
12,186
629
414
65
192
192
388,741
328,962
286,363
3,594
193
76
2
1
0
0
910
110
11
3,819
13
3
Cribriform carcinoma
3
3
2 Transitional cell carcinoma of the Prostate
2 Salivary gland type tumours of the Prostate
3
3
Basaloid carcinoma
3
1 TUMOURS OF THE TESTIS and PARATESTIS
2 Adenocarcinoma and variants of the paratestis
3
3
3
3
3
Collecting duct and rete testis carcinoma
3
Transitional cell carcinoma, NOS
2 Malignant/Immature Teratomas of the Testis
3
3
Teratocarcinoma
3
Choriocarcinoma combined with other germ cell elements
3
Teratoma with malignant transformation
2 Germ cell tumour Seminomatous of the Testis
3
Seminoma, NOS
3
Spermatocytic seminoma
2 Germ cell tumour non Seminomatous of the Testis
3
Embryonal adenocarcinoma, NOS
3
Yolk sac tumour
2 Trophoblastic Tumours of the Testis
3
2 Sex Cord Tumours of the Testis
3
Leydig cell tumour malignant
3
Sertoli cell carcinoma
3
Malignant sex cord/gonadal stromal tumours
1 EPITHELIAL TUMOURS OF THE PENIS
0.361
0.029
0.014
0.06
0.00
0.001
NE
NE
3.15
0.00
0.00
NE
NE
NE
NE
NE
0.83
0.214
0.104
0.034
0.001
1.74
1.673
0.027
0.36
0.272
0.05
0.02
0.014
0.02
0.014
0.003
NE
0.62
2,801
223
108
518
13
9
0
0
25,510
12
1
0
0
0
0
0
6,748
1,659
807
266
10
14,089
12,970
213
2,935
2,106
388
140
110
178
105
27
0
5,058
14
2 Squamous cell carcinoma and variants of the Penis

3
Squamous carcinoma
3
Verrocous carcinoma
3
Squamous cell carcinoma, sarcomatoid
3
3
Basaloid carcinoma
2 Adenocarcinoma and variants of the Penis
3
Extramammary Paget disease
3
3
3
Mixed tumour malignant, NOS
3
3
1 EPITELIAL TUMOURS OF THE KIDNEY
2 Renal cell carcinoma and variants
3
Adenocarcinoma NOS
3
Renal cell adenocarcinoma
3
3
3
Renal cell carcinoma chromophobe type
3
Collecting duct carcinoma
3
Xp translocation carcinoma
3
Carcinoma associated with neuroblastoma
3
Renal medullary carcinoma
3
Mucinous tubular and spindle cell carcinoma
2 Squamous cell carcinoma spindle cell type of the Kidney
2 Squamous cell carcinoma and variants of the Kidney
1 EPITHELIAL TUMOURS OF THE PELVIS, URETHER and URETHRA
2 Transitional cell carcinoma of the Pelvis, Ureter and Urethra
3
3
Transitional cell carcinoma spindle cell
3
Lymphoepithelioma-like carcinoma
3
Transitional cell carcinoma, giant cell
3
Transitional cell carcinoma, micropapillary
0.57
0.432
0.036
0.001
0.00
NE
0.00
0.003
NE
0.001
NE
NE
NE
10.56
8.36
0.477
5.116
1.988
0.136
0.017
0.002
NE
NE
NE
NE
0.01
0.04
1.59
1.37
0.005
0.001
NE
NE
NE
4,649
3
257
7
2
0
40
19
0
6
0
0
0
85,671
67,788
3
39,640
15,402
1,049
132
14
0
0
0
0
56
284
12,888
11,139
39
5
0
0
0
15
2 Squamous cell carcinoma and variants of the Pelvis, Ureter and Urethra
3
Verrucous carcinoma
2 Adenocarcinoma and variants of the Pelvis, Ureter and Urethra
3
3
3
2 Salivary gland-type tumours of the Pelvis, Ureter and Urethra
3
Basaloid carcinoma
3
3
1 EPITHELIAL TUMOURS OF THE BLADDER
2 Transitional cell carcinoma of the Bladder
3
3
Transitional cell carcinoma spindle cell
3
Transitional cell carcinoma with squamous differentiation
3
3
3
Transitional cell carcinoma micropapillary
2 Squamous cell carcinoma and variants of the Bladder
3
Verrucous carcinoma
2 Adenocarcinoma and variants of the Bladder
3
3
3
2 Salivary gland type tumours of the Bladder
3
Basaloid carcinoma
3
3
1 EPITHELIAL TUMOURS OF THE EYE AND ADNEXA
2 Squamous cell carcinoma and variants of the Eye and Adnexa
3
Squamous carcinoma
3
Basal cell carcinoma
2 Adenocarcinoma and variants of the Eye and Adnexa
3
Adenocarcinoma NOS
0.05
0.00
0.04
0.001
NE
NE
0.00
0.00
NE
NE
20.18
17.48
0.057
0.008
NE
0.001
0.001
0.00
0.42
0.001
0.29
0.014
0.013
0.012
0.00
0.001
0.001
0.00
0.16
0.04
0.033
0.001
0.01
0.001
417
2
301
7
0
0
2
2
0
0
163,624
141,716
440
62
0
8
7
3
3,436
9
2,331
108
102
91
9
5
5
2
1,286
304
235
4
90
6
16
3
3
1
2
3
2
3
3
1
2
3
3
2
3
3
1
2
3
3
3
3
1
2
1
2
1
2
3
3
3
3
3
3
2

EPITHELIAL TUMOURS OF THE MIDDLE EAR
Squamous cell carcinoma and variants the Middle Ear
Squamous carcinoma
Adenocarcinoma and variants the Middle Ear
Adenocarcinoma NOS
MALIGNANT MESOTHELIOMA
Mesothelioma of the pleura and pericardium
Epithelioid malignant mesothelioma
Sarcomatoid malignant mesothelioma
Mesothelioma of the peritoneum and tunica vaginalis
Epithelioid malignant mesothelioma
Sarcomatoid malignant mesothelioma
MALIGNANT SKIN MELANOMA
Malignant skin melanoma
Superficial spreading melanoma
Nodular melanoma
Lentigo maligna melanoma
Acral lentiginous melanoma malignant
MALIGNANT MELANOMA OF THE MUCOSA
Malignant melanoma of the mucosa
MALIGNANT MELANOMA OF THE UVEA
Malignant melanoma of the uvea
EPITHELIAL TUMOURS OF THE SKIN
Basal cell carcinoma of the Skin
Basal cell carcinoma NOS
Basosquamous carcinoma
Multifocal superficial basal cell carcinoma
Basal cell carcinoma nodular
Basal cell carcinoma fibroepithelial
Adenoid basal carcinoma
Squamous cell carcinoma and variants of the Skin
0.005
0.001
0.03
0.02
0.017
0.00
0.002
0.001
1.91
1.61
0.244
0.037
0.13
0.018
0.001
12.44
12.44
4.811
1.624
0.628
0.143
0.51
0.51
0.65
0.65
49.02
32.52
31.388
1.648
0.844
0.106
0.032
0.007
16.35
37
6
245
180
120
29
13
6
15,456
13,056
1,745
261
1,014
126
8
100,883
100,883
37,282
12,583
4,867
1,108
4,132
4,132
5,301
5,301
397,503
263,713
243,224
12,774
6,538
823
245
55
132,597
17
3
Squamous carcinoma
3
Verrucous carcinoma
3
3
Pseudo vascular/ Squamous cell carcinoma adenoid
3
1 ADNEXAL CARCINOMA OF THE SKIN
2 Adnexal carcinoma of the skin
3
Nodular hidradenoma, malignant
3
3
3
Paget disease extra mammary
3
Apocrine adenocarcinoma
3
3
Pilomatrix carcinoma
3
Eccrine poroma, malignant
3
Mixed tumour malignant, NOS
3
Sclerosing sweat duct carcinoma
3
Malignant eccrine spiradenoma
3
3
Eccrine papillary adenocarcinoma
1 EMBRYONAL NEOPLASMS
2 Neuroblastoma and ganglioneuboblastoma
2 Nephroblastoma
2 Retinoblastoma
2 Hepatoblastoma
2 Pulmonary blastoma
2 Pancreatoblastoma
1 EXTRAGONADIC GERM CELL TUMOURS
2 Extragonadic malignant/Immature Teratomas
3
Teratoma malignant
3
3
Teratocarcinoma
3
Choriocarcinoma combined with other germ cell elements
2 Extragonadic Germ cell tumour
15.287
0.068
0.036
0.01
0.005
0.28
0.28
0.079
0.064
0.02
0.018
0.008
0.004
0.004
0.003
0.002
0.002
0.001
0.00
0.00
0.34
0.12
0.14
0.05
0.02
0.00
0.00
0.13
0.04
0.033
0.006
0.004
0.001
0.09
118,461
524
281
75
38
2,247
2,247
503
611
152
140
59
33
31
26
14
12
7
2
2
2,789
982
1,149
437
181
34
6
1,028
337
231
42
26
7
691
18
3
Dysgerminoma/Seminoma
3
Embryonal adenocarcinoma
3
Yolk sac tumour
3
3
Polyembryoma
1 SOFT TISSUE SARCOMA
2 Soft tissue sarcoma of the Head and Neck
3
Sarcoma NOS
3
Epithelioid sarcoma
3
Desmoplastic small round cell tumour
3
Fibrosarcoma
3
Fibromyxosarcoma
3
Infantile fibrosarcoma
3
Myxoinflammatory fibroblastic sarcoma
3
Malignant fibrous histiocytoma
3
DFSP
3
Well differentiated liposarcoma
3
Myxoid liposarcoma
3
Pleomorphic liposarcoma
3
Mixed type liposarcoma
3
Dedifferentiated liposarcoma
3
Leiomyosarcoma
3
Pleomorphic rhabdomyosarcoma
3
Extrarenal rhabdoid tumour
3
Synovial sarcoma
3
Clear cell sarcoma of soft tissue
3
Epithelioid angiosarcoma
3
Epithelioid hemangioendothelioma
3
Extraskeletal osteosarcoma
3
Extraskeletal myxoid chondrosarcoma
3
Malignant peripheral nerve sheath tumours
3
3
3
3
Intimal Sarcoma
Low grade fibromyxoid sarcoma
Low grade myofibroblastic sarcoma
PEComas
0.054
0.01
0.011
0.034
0.00
4.75
0.29
0.03
0.001
0.00
0.012
0.003
0.00
NE
0.039
NE
0.005
0.002
0.001
NE
0.00
0.054
0.002
0.00
0.005
NE
0.025
0.00
0.00
0.00
0.019
389
75
78
242
1
38,527
2,356
212
10
1
85
21
2
0
280
0
33
16
4
0
3
387
13
2
35
0
180
2
2
2
135
NE
NE
NE
NE
0
0
0
0
19
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Sclerosing epithelioid fibrosarcoma

Undifferentiated pleomorphic sarcoma
Soft tissue sarcoma of the Limbs *
Soft tissue sarcoma of the Superficial Trunk *
Soft tissue sarcoma of the Mediastinum *
Soft tissue sarcoma of the Heart *
Soft tissue sarcoma of the Breast *
Soft tissue sarcoma of the Uterus *
Soft tissue sarcoma of the Genitourinary (other) *
Soft tissue sarcoma of the other Viscera *
Soft tissue sarcoma of the Paratesticular region *
Soft tissue sarcoma of the Retroperitoneum and Peritoneum *
Soft tissue sarcoma of the Pelvis *
Soft tissue sarcoma of the Skin *
Soft tissue sarcoma of the Paraorbital region *
Soft tissue sarcoma of the Brain and other Nervous System *
* includes all the Layer 3 entities listed for the soft tissue of the Head and Neck
2 Embryonal rhabdomyosarcoma of the Soft Tissue
2 Alveolar rhabdomyosarcoma of the Soft Tissue
2 Ewings family tumours of the Soft Tissue
1 BONE SARCOMA
2 Osteogenic sarcoma
3
Conventional osteosarcoma
3
Teleangectatic osteosarcoma
3
Small cell osteosarcoma
3
Paraosteal osteosarcoma
3
High grade surface osteosarcoma
3
Low grade central osteosarcoma
3
Periosteal osteosarcoma
3
Secondary osteosarcoma
2 Chondrogenic sarcomas
3
Chondrosarcoma
3
Mesenchymal chondrosarcoma
3
Clear cell chondrosarcoma
NE
0.035
1.03
0.47
0.03
0.01
0.19
0.5
0.24
0.51
0.03
0.29
0.01
0.31
0.01
0.2
0.06
0.06
0.03
0.02
0.8
0.23
0.201
0.005
0.002
0.009
0.001
NE
NE
NE
0.24
0.23
0.005
0.00
0
247
8,376
3,824
218
121
1,513
4,035
1,939
4,129
265
2,344
118
2,514
56
1,621
495
495
263
193
6,523
1,850
1,738
35
11
62
4
0
0
0
1,982
1,642
33
2
20
3
Dedifferentiated chondrosarcoma
2 Notochordal sarcomas, Chordoma
3
Chordoma
2 Vascular sarcomas, Angiosarcoma
3
Angiosarcoma
2 Ewings family of tumours
3
Ewings sarcoma/PNET
2 Epithelial tumours , Adamantinoma
3
Adamantinoma
2 Other high grade sarcomas (fibrosarcoma, malignant fibrous histyocitoma)
3
Fibrosarcoma
3
Malignant fibrous histyocitoma
1 GASTROINTESTINAL STROMAL SARCOMA
2 Gastrointestinal stromal sarcoma
1 KAPOSI SARCOMA
2 Kaposi sarcoma
1 NEUROENDOCRINE CARCINOMAS
2 Well differentiated endocrine tumours, carcinoid
2 Well differentiated endocrine tumours, atypical carcinoid
2 Poorly differentiated endocrine carcinoma (lung excluded)
3
Small cell endocrine carcinoma
3
Large cell endocrine carcinoma
2 Mixed endocrine-exocrine carcinoma
2 Endocrine carcinoma of Thyroid gland
3
3
Mixed medullary-follicular carcinoma
2 Well differentiated endocrine carcinoma, not functioning of Pancreas and Digestive tract
3
Carcinoid tumour, NOS
3
Islet cell carcinoma
2 Well differentiated endocrine carcinoma, functioning of Pancreas and Digestive tract
3
Insulinoma, malignant
3
Glucagonoma, malignant
3
Somatostatinoma, malignant
3
Gastrinoma, malignant
0.001
0.04
0.045
0.00
0.003
0.13
0.12
0.01
0.008
0.02
0.006
0.012
0.07
0.07
0.36
0.36
2.52
0.37
0.00
0.52
0.342
0.514
0.00
0.22
0.221
0.001
1.25
1.26
0.034
0.02
0.014
0.003
NE
0.006
9
355
320
26
23
1,021
857
70
60
147
43
87
536
536
2,925
2,925
20,466
2,961
6
4,225
2,446
3,674
17
1,772
1,579
6
10,152
9,005
245
200
98
24
0
46
21
3
VIP-oma
3
Other ectopic hormone producing tumours
2 Endocrine carcinoma of Skin
3
Merkel cell carcinoma
1 CARCINOMA OF ENDOCRINE ORGANS
2 Carcinomas of Pituitary gland
3
Pituitary carcinoma, NOS
2 Carcinomas of Thyroid gland
3
3
follicular carcinoma, NOS
3
3
Undifferentiated/anaplastic carcinoma
3
3
Mucinous carcinoma
3
Spindle cell tumour with thymous-like differentiation (SETTLE)
3
Carcinoma showing thymus-like differentiation (CASTLE)
2 Carcinomas of Parathyroid gland
3
Parathyroid carcinoma
2 Carcinoma of adrenal gland
3
Adrenal cortical carcinoma
1 GLIAL TUMOURS OF THE CNS and PINEAL GLAND
2 Astrocytic tumours of the CNS
3
Astrocytoma, NOS
3
Astrocytoma, anaplastic
3
Glioblastoma
3
Gliosarcoma
3
Giant cell glioblastoma
3
Astroblastoma
3
Protoplasmic astrocytoma
3
Gliomatosis cerebri
3
Pleomorphic xanthoastrocytoma
3
Pilocytic and Pilomixoid astrocytoma
3
Oligoastrocytoma
3
Subependymal giant cell astrocytoma
0.001
NE
0.13
0.142
4.16
0.04
0.009
3.68
2.632
0.724
0.001
0.203
0.001
0.00
0.00
NE
0.02
0.007
0.18
0.073
5.35
4.79
0.796
0.39
2.504
0.025
0.022
0.016
0.01
0.009
0.009
0.185
0.108
NE
8
0
1,082
1,018
33,757
333
69
29,803
18,821
5,173
4
1,459
9
3
1
0
179
57
1,471
520
43,344
38,864
5,691
2,789
17,902
177
155
116
71
63
62
1
772
0
22
2
3
3
2
3
3
3
3
1
2
3
3
3
3
3
3
3
3
2
1
2
1
2
3
3
3
3
3
2
3
1
2
3
3
Oligodendroglial tumours of the CNS

Oligodendroglioma
Oligodendroglioma, anaplastic
Ependymal tumours of the CNS
Ependymoma, NOS
Ependymoma, anaplastic
Subependymoma
Myxopapillary ependymoma
NON GLIAL TUMOURS OF THE CNS AND PINEAL GLAND
Embryonal tumours of the CNS
Medulloblastoma
Desmoplastic nodular medulloblastoma
PNET
Anaplastic ganglioglioma
Atypical teratoid/rhabdoid tumour
Medulloepithelioma, NOS
Large cell and anaplastic medulloblastoma
Pineoblastoma
Choroid plexus carcinoma of the CNS
MALIGNANT MENINGIOMAS
Malignant meningiomas
GLIAL TUMOURS OF THE NERVES, AUTONOMIC NERVOUS SYSTEM AND PARAGANGLIA
Astrocytic tumours of the Nerves, Autonomic Nervous System and Paraganglia
Astrocytoma, NOS
Astrocytoma anaplastic
Glioblastoma
Gliosarcoma
Ganglioglioma, anaplastic
Ependymal tumours of the the Nerves, Autonomic Nervous System and Paraganglia
Ependymoma, NOS
NON-GLIAL TUMOURS OF THE NERVES, AUTONOMIC NERVOUS SYSTEM AND PARAGANGLIA
Embryonal tumours of the Nerves, Autonomic Nervous System and Paraganglia
PNET
Olfactory neuroblastoma
0.35
0.24
0.089
0.2
0.159
0.03
NE
NE
0.22
0.22
0.112
0.012
0.055
0.002
0.001
NE
NE
0.015
0.01
0.15
0.15
0.01
0.00
0.003
0.001
0.001
0.00
0.00
0.01
0.005
0.1
0.07
0.046
0.00
2,863
1,716
637
1,617
1
214
0
0
1,816
1,766
799
84
394
13
6
0
0
109
50
1,225
1,225
82
40
19
8
5
1
1
42
40
800
599
328
3
23
3
Olfactory neuroepithelioma
3
Olfactory neurogenic tumour
3
Teratoid medulloepithelioma
3
Neuroepithelioma, NOS
2 Paraganglioma
1 LYMPHOID DISEASES
2 Classical Hodgkin Lymphoma
3
Lymphocyte-rich
3
Mixed cellularity
3
Lymphocyte-depleted
3
Nodular sclerosis
2 Hodgkin lymphoma nodular lymphocyte predominance
2 Composite Hodgkin/NHL
2 Precursor B/T lymphoblastic leukaemia/lymphoblastic lymphoma
2 Non Hodgkin Mature T cell and NK-cell neoplasms
3
T cutaneous lymphoma (Sezary syn, Mycosis fung)
3
Other T cell lymphomas
2 Non Hodgkin, Mature B cell lymphoma
3
Small cell lymphocytic lymph/chronic lymphatic leukaemia
3
Mantle cell/lymph centrocytic
3
Prolymphocytic leukaemia, B cell
3
Lymphoplasmacitic/Waldenstrm macroglobulinemia
3
Burkitt leukaemia/lymphoma
3
Diffuse B lymphoma
3
Splenic/nodal marginal zone/extra nodal MALT type
3
Follicular B lymphoma
3
Hairy cell leukaemia
3
Plasmocitoma/multiple mieloma
3
Heavy chain disease
1 ACUTE MYELOYD LEUKAEMIA AND RELATED PRECURSOR NEOPLASMS
2 Acute Myeloid Leukemia (AML) with recurrent genetic abnormalities
3
AML with t(8;21)(q22;q22); AML 1/ETO)
3
AML with inv(16)(p13.1q22)or t( 16; 16)(p13.1q22), (CBFbeta/MYH )
3
Acute promyelocytic leukemia (AML with t(15;17) and variants
3
Acute myeloid leukemia 11q23 abnormalities
0.00
0.00
0.00
0.004
0.02
29.17
2.38
0.094
0.413
0.043
1.249
0.06
0.01
1.28
0.97
0.54
0.43
17.51
4.641
0.352
0.051
0.809
0.177
2.75
0.323
2.131
0.283
5.818
0.002
3.7
0.11
0.002
0.001
0.11
0.00
1
1
1
28
201
236,546
19,318
675
2,953
311
8,940
469
42
10,384
7,870
3,859
3,074
141,972
33,181
3
363
6
1,263
19,662
2,304
15,241
2
41,601
13
29,982
921
11
8
785
1
24
2 Acute myeloid leukemia NOS (FAB or WHO type not specified)

2 AML with myelodysplasia-related changes and RAEBT-T
3
AML with myelodisplasia-related changes
3
Refractory Anemia with excess blasts in transformation (RAEBT-T)
2 Therapy-related myeloid neoplasms
3
Therapy related myelodysplastic syndrome NOS
3
Therapy-related myeloid neoplasms
2 Acute Myeloid Leukemia no categorized and other AML
3
Acute myeloid leukemia minimally differentiation
3
Acute myeloid leukemia without maturation
3
Acute myeloid leukemia with maturation
3
Acute myelomonocytic leukemia
3
Acute myeloid leukemia MVI type
3
Acute monoblastic and monocytic leukemia
3
Acute erytroid leukemia
3
Acute basophilic leukemia
3
Acute megakaryoblastic leukemia
3
Acute panmyelosis with myelofibrosis
3
Acute leukemias with ambiguous lineage
2 Myeloid sarcoma
2 Blastic plasmocytoid dendritic cell neoplasm
1 MYELOPROLIFERATIVE NEOPLASMS
2 Chronic myeloid leukemia
3
Chronic myeloid leukemia NOS
3
Chronic myelogenous leukemia BCRABL positive
2 Myelosclerosis with myeloid metaplasia
2 Essential thrombocythemia
2 Polycythemia vera
2 Mast cell tumours
3
Mastocytoma NOS/mast cell sarcoma
3
Malignant mastocytosis
3
Mast cell leukaemia
2 Myeloproliferative diseases, others
3
Chronic myeloproliferative disease NOS
2.84
0.05
0.003
0.042
0.00
0.00
0.00
0.48
0.496
0.009
0.016
0.032
0.172
0.06
0.123
0.001
0.00
0.02
0.045
0.003
NE
3.07
1.26
1.231
0.006
0.12
0.48
0.66
0.02
0.002
0.012
0.001
0.53
0.551
23,039
399
22
280
9
2
3
3,916
3,550
65
117
230
1,229
427
883
4
2
143
321
21
0
24,859
10,185
8,801
43
1,010
3,886
5,353
125
13
84
9
4,284
3,939
25
3
Chronic neutrophilic leukemia
3
Hypereosinophilic syndrome
1 MYELODYSPLASTIC SYNDROME
2 Myelodysplastic syndrome
3
Refractory anemia
3
Refractory anemia with sideroblasts
3
Refractory anemia with excess blasts
3
Refractory cytopenia with multilineage dysplasia
3
Myelodysplastic syndrome with Vq syndrome
3
Myelodysplastic syndrome NOS
1 MYELOSDYSPLASTIC/MYELOPROLIFERATIVE DISEASES
2 Chronic myelomonocytic leukemia NOS
2 Juvenile myelomonocytic leukemia
2 Atypical chronic myeloid leukemia BCRABL negative
1 HISTIOCYTIC AND DENDRITIC CELL NEOPLASMS
2 Histiocytic and dendritic cell neoplasms
3
Histiocytic sarcoma
3
Langherans cell histiocytosis
3
Langherans cell sarcoma
3
Interdigitating dendritic cell sarcoma
3
Follicular dendritic cell sarcoma
3
Fibroblastic reticular cell tumour
0.00
0.001
1.49
1.49
0.199
0.095
0.15
0.00
0.00
1.08
0.29
0.29
0.00
0.00
0.05
0.05
0.003
NE
NE
0.001
0.00
NE
3
8
12,082
12,082
1
681
1
2
3
8
2,328
2,319
3
6
394
394
25
0
0
4
3
0
26

List of Rare Cancers

Uploaded by

Copyright:

Available Formats

You might also like

List of Rare Cancers

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

List of Rare Cancers

Uploaded by

Copyright:

Available Formats

Rare cancers are those with an incidence rate 6/100,000

Epithelial tumours of the major salivary glands

2 Undifferentiated carcinoma of the Oesophagus

2 Acinar cell carcinoma of the Pancreas

2 Adenocarcinoma and variants of the Thymus

2 Squamous cell carcinoma and variants of the Penis

Adenoid cystic carcinoma

Sclerosing epithelioid fibrosarcoma

Oligodendroglial tumours of the CNS

2 Acute myeloid leukemia NOS (FAB or WHO type not specified)

You might also like