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United States: (12) Patent Application Publication (10) Pub. No.: US 2002/0147318 A1
United States: (12) Patent Application Publication (10) Pub. No.: US 2002/0147318 A1
Cho et al.
(54) PREPARATION METHOD OF WATER
SOLUBLE CARBOXYLMETHYL CHITOSAN
HAVING ANTI-LIPID PEROXIDATION
ABILITY
Publication Classi?cation
(51)
Int. Cl? .
(52)
C08B 37/08
(57)
ABSTRACT
09/834,610
(22) Filed:
(30)
Apr. 9, 2001
US 2002/0147318 A1
1-A
P 00
alM5atbs3iBogrpnAhtmion
2
I
PA
0.0
0. 000
0. 002
0. 004
0. 006
0. 008
concentratioMmg/ml)
FIG. 1A
100
1-B
(I) O
ipnehrcbto(%)
CD 0
.p. O
concentration(mg/ml)
FIG. 1B
O (O
P 00
Q N
Q 0)
P 01
US 2002/0147318 A1
2-A
Q o
lMab5atisD3ogrAphntimo
0. 000
0. 002
0.004
0.006
0.000
concentration (mg/ml)
FIG. 2A
O: Q
inpherbcto(%)
2-B
1
NGOA01Q0CD
|
L C)
O
0.001
FIG.2B
US 2002/0147318 A1
A o
3-A
O no
5ata3blMsoirnBpgmtihAotn
CD 0)
O A
0.0
0.000
0.003
0.006
0.000
0.012
ooncentration(mg/ml)
100
peinrhcbt(o%)
3-B
AO
0.000
0.003
0.000
0.009
concentration(mg/ml)
FIG.3B
0.012
US 2002/0147318 A1
EXAMPLE 2
tion;
[0008] FIG. 2 shoWs the anti-lipid peroxidation effect of
CM chitosan frorn crab according to the present invention;
[0009] FIG. 3 shoWs the anti-lipid peroxidation effect of
Trolox;
DESCRIPTION OF THE INVENTION
EXAMPLE 1
[0010]
Chitosan
US 2002/0147318 A1
antioxidant ability.
[0022] More particularly, FIG. 1A shoWs that MDA, the
product of lipid peroxidation, is monotonically decreased as
the added amount of Water soluble CM chitosan derived
summarized as folloWs:
dant ability.
[0026] More particularly, FIG. 2A shoWs that MDA, the
product of lipid peroxidation, is monotonically decreased as
I claim:
ric acid, acetic acid, nitric acid, phosphoric acid, oxalic acid,
and butyric acid.