Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 5

Subject

:pharmacology

Republic of Yemen
University of science
and
Technology
Ibb-branch

Level :one

Name

Answer all the question below

1 Complete the table with suitable substance


Item
lipophilic -blockers
Examples

Hydrophilic -blockers

1-..

1-Atenolol

2-

2- ..

3-..

3-.

Gastrointestinal
absorption
Blood brain barrier
passage
Metabolism

Well

Less

Rapid

Duration

Long Acing

..

Choose The correct answer:


1.
Drug require acidic media to dissolve & coats the ulcerative
tissue

A.
B.

Pirenzepine
Somatostatin
C. Sucralfate/
D. Pantoprazole
2.Misoprostol
A. stimulates secretion of HCL
B. stimulates secretion of mucus & bicarbonate/
C. It is a ethyl analog of PGE1
D. It is approved for prevention of ulcer induced by SAIDs

3.

4.

Omeprazole bind to androgens similar to

A.
B.
C.
D.

Cimetidine./
Famotidin.
Ranitidine.
Nizatidine.

Esomeprazoie is

A.
B.

D- isomer of omeprazole .
undergoes less first-pass metabolism in the

liver ./
C. has a more plasma clearance as compared with
omeprazole.
D. act by reversible binding to the proton pump.

5. Mechanism of action of Magaldrate (Mg +AL) salts is


A. H2 antagonist
B. Proton Pump inhibitors
C. Anti-cholinergics
D. Neutralize gastric acid/

6. VE inotropic effect mean


A. Heart Rate
B. contractility /.
C. A-V conduction.
D. COP (Cardiac out-Put).
7. Drug more effective in Benign prostatic hyperplasia (BPH) is
A. Prazosin
B. Doxazosin
C. Tamsulosin/
D. Phenotlamine
8. All of the following are actions of Selective 2 agonists EXCEPT
A. Produce broncho dilatation
B. bronchial secretions & release of allergic mediators from mast cells
C. Relax uterus & produce V.D
D. glycogenolysis& insulin release./

9. Administration of adrenaline
A. Intra-muscular I.M
B. Intra-venous I.V
C. Intra-cardiac I.C/
D. Intra-arterial I.A

10.Dryness of eye & skin caused by


A. Timolol
B. Practolol/
C. Esmolol
D.Nebivolol

Put the suitable drug in the suitable blanks?


1-Noradrenaline 2- Adrenaline 3- Dobutamine 4- Salbutamol
5-Fenoldopa
6- Dopamine 7- Isoxsuprine 8- Isoprenaline 9- Methoxamine 10yohimbine
Mechanism of action

Stimulates directly all types of receptors .

Drug
Isoprenaline
Noradrenaline
Methoxamine
Adrenaline

Stimulates directly D1 , 1 , receptors.

Dopamine

Stimulates directly 1 receptors

Dobutamine
yohimbine
Fenoldopa
Salbutamol
- Isoxsuprine

Stimulates directly 1 , 2, 3 but no -effect


Stimulates directly -1 , 3 no 2

Selective 1 agonists

Selective 1 blockers
D1 receptor agonist

Selective 2 agonists
Non selective -agonists

Write short note about only one of the


following:
A. Treatment of H. Pylori.
B. Nasal decongestant.

Best wish By Dr.Mohammad Dammag

Best wish By Dr.Mohammad Dammag


1

You might also like