Professional Documents
Culture Documents
Results and Observations 6.1 Preparation of Extract and Properties
Results and Observations 6.1 Preparation of Extract and Properties
Results and Observations 6.1 Preparation of Extract and Properties
S.N
o
1
Methanolic extract
Carbohydrates
Proteins
Flavanoids
Steroids
Saponin
Glycosides
Cardiac
glycosides
Starch
Alkaloids
+ ve:
Page 59
MRIPS
Page 60
MRIPS
Page 61
Treatment
Dose
gastric juice
Free
Total
Ph
Control
50mg/kg
in ml
6.74
acidity
84.109
acidity
115.21
1.42
Standard
40mg/kg
0.13
2.33
3.12
35.25
2.42
42.62
0.51
6.7
100mg /kg
0.70**
4.97
2.44**
80.14
1.16**
106.72
0.18**
2.81
200mg/ kg
0.68*
2.86
2.33
35.80
2.53*
47.34
0.30*
6.60
3
4
MELI
MELI
0.35**
1.98
1.98*
S.E.M. of 6 rats / treatment
0.25**
Graph No.1: Effects of Methanolic extract of Leea indica leaf on Volume of gastric
MRIPS
Page 62
8
7
6
5
Vol Of Gastric Juice(ml) 4
Control
Standard
MELI(100mg)
MELI(200mg)
1
0
Treatment
Graph No.2: Effects of Methanolic extract of Leea indica leaf on free acidity in
pylorus ligation induced ulcer
100
80
60
Free
Control
Acidity(mE/L/100
Standard gms)
MELI(100mg)
40
20
MRIPS
Page 63
MELI(200mg)
150
100
Total
Control
Acidity(mE/L/100
Standard gms)
MELI(100mg)
MELI(200mg)
50
10
6
phControl
Standard
MELI(100mg)
MRIPS
Page 64
MELI(200mg)
MRIPS
Page 65
S. No
Treatment
Dose
Control
50mg/kg
Ulcer index
6.44.0.11
2
Standard
MRIPS
35.46
40mg/kg
(Ranitidine)
3
MELI
100mg/kg
MELI
200mg/kg
% protection
1.80.69**
79.15
6.910.35***
45.63
1.73 0.42**
75.93
Page 66
10
6
Ulcer
Control
Index
Standard
MELI(100mg)
MRIPS
Page 67
MELI(200mg)
(40mg/kg)
MELI-100mg/kg
MRIPS
MELI-200mg/kg
Page 68
MRIPS
Page 69
Table 6: Effect of Methanolic extract of Leea indica leaves on ulcer index and
their % protection in aspirin induced ulcer in rats
Gr.no
1
Treatment
Control
(Aspirin)
Standard
(Ranitidine)
MELI
MELI
Dose
200mg/kg
Ulcer index
7.45
%protection
40.51
40mg/kg
0.54
1.95
77.85
100mg/kg
0.34**
5.25
46.42
200mg/kg
0.84***
1.65
0.12**
73.14
Graph No.6: Effect of Methanolic extract of Leea indica leaves on ulcer index
MRIPS
Page 70
8
7
6
5
Total
Control
Acidity(mE/L/100
Standard gms)
MELI(100mg)
4
MELI(200mg)
3
2
1
0
Fig. 7: Effect of Methanolic extract of Leea indica leaf on ulcer index and their %
MRIPS
Page 71
Control Aspirin
100mg/kg MELI
MRIPS
200mg/kg MELI
Page 72