ENDOCRINOLOGY

1. Hypothalamus & Pituitary Gland: hypothalamus and pituitary axes; HYPOPITUITARISM

Describe anterior pituitary hormones action and regulation
Describe the conditions of hypopituitarism: etiology, clinical features and diagnostic testing
2. PITUITARY gland: pituitary adenomas, Diabetes Insipidus, SIADH
Describe the diseases affecting the posterior pituitary (Diabetes Insipidus and SIADH) clinical features, etiology and
diagnostic testing
Knowledge of epidemiology of pituitary adenoma
Describe the clinical features common to pituitary adenomas
Identify the major clinical manifestations and diagnostic testing related to acromegaly, non-functioning pituitary adenomas
(NFA), PRL-secreting adenomas, Cushing disease.
3. The THYROID Gland: Diagnostic Evaluation of Patients with Thyroid Disorders, hypo-hyperthyroidism
Describe thyroid hormones action and regulation
Describe the conditions of hypo and hyperthyroidism: etiology, clinical features and diagnostic testing
4. The Thyroid Gland: goiter, nodules and THYROID CANCER
Describe the conditions of goiter: etiology, clinical features and diagnostic testing
Describe the conditions of thyroid nodules and thyroid cancer: etiology, clinical features, diagnosis and follow up
5. GLUCOCORTICOIDS & Adrenal ANDROGENS
Describe adrenal hormones action and regulation
Describe the conditions of hypercortisolism: etiology, clinical features and diagnostic testing
Describe the conditions of hypoadrenalism: etiology, clinical features and diagnostic testing
6. Endocrine HYPERTENSION
Identify the main causes of endocrine hypertension: Pheochromocytoma, hyperaldosteronism
7. FEMALE Reproductive Endocrinology and Infertility
Describe Ovarian Hormones Action and regulation

Describe the conditions of hypogonadism: etiology, clinical features and diagnostic testing
Describe the conditions of hirsutism: definition, etiology, clinical testing and

8. MALE Reproductive Endocrinology

Describe testicular hormones action and regulation
Describe the conditions of hypogonadism: etiology, clinical features, diagnostic testing and follow up
Describe the condition of gynecomastia: etiology and diagnostic testing
9. Hormones and Disorders of MINERAL METABOLISM
Describe PTH and vitamin D action and regulation
Describe the conditions of hyperparathyroidism: etiology, clinical features, diagnosis and follow up
Describe the condition of hypoparathyroidism: etiology and diagnostic testing
Describe the conditions of secondary osteoporosis
10. MEN

Describe the conditions MEN1: genetics, clinical features, diagnosis and follow up
Describe the conditions MEN2: genetics, clinical features, diagnosis and follow up
Recall of other MEN: Carney complex, McCune-Albright Syndrome

11. DIABETES
Recall glucose homeostasis regulation

Describe the conditions of diabetes mellitus: genetics, clinical features, diagnosis testing, complications and follow up

PHARMACOLOGY
1. Pharmacology of DIABETES
Outline the major features of insulin secretion, metabolism, mechanism of action and physiological effects
Briefly define diabetes
Illustrate the goals of the pharmacological treatment of diabetes
Describe the different insulin preparations used in the treatment of diabetes
Describe the mechanisms of action, pharmacological effects, pharmacokinetics and adverse effects of the various groups of
hypoglycemic drugs
Explore new pharmacological approaches to the treatment of diabetes
2. GLUCOCORTICOIDS
Outline the major features of glucocorticoid synthesis, mechanism of action and physiological effects
Describe the mechanisms of action involved in the anti-inflammatory and immunosuppressive effects of glucocorticoid drugs
Describe the pharmacokinetics of glucocorticoids drugs
3. ESTROGENS, PROGESTINS and treatments for THYROID DISEASES
Describe the mechanism of action and the physiological and pharmacological effects of estrogens and progestins

Describe the adverse effects and contraindications of estrogens and progestins

Illustrate the current strategies for the use of estrogens and progestins in oral contraceptives and in hormone replacement
therapy in menopause

Describe the pharmacology and clinical use of selective estrogen receptor modulators (SERMs)

Describe the pharmacological treatments for thyroid diseases

IMAGING

Discuss the applications of CT and MRI in the study of diseases of the adrenal glands.