Name of Drug

Action &
Indication

Classification:

INDICATION

Ketoanalogues
and nitrogenfree essential
amino acids

- Chronic Renal
Insufficiency
together with
low protein,
high caloric diet
in compensated
and
decompensated
retention

- Ketosteril
600mg/tab

Mechanism of
action
- Normalizes
metabolic
process,
promotes
recycling
product
exchange.Reduc
es ion
concentration of
potassium,
magnesium and
phosphate

Adverse Effects

Nursing
Responsibilities

- Tetracycline effect - Observe 12 Rights

Ca absorption
in medication
administration
- Assess for any
hypersensitivity
reaction to
KETOSTERIL
- As uremic
symptoms
improve Al
hydroxide should
be reduced

Name of Drug

Action &
Indication

Classification:
Antienemics
Vitamins

- Folic
acid
mg/tab

INDICATION
- Prevention and
treatment of
megaloblastic
and macrocytic
anemia
5
Mechanism of
action
- Required for
protein
synthesis and
red blood cell
function
stimulates the
production of
red blood cells
and platelets

Adverse Effects

Nursing
Responsibilities

CNS- irritability, - Asses patient for

difficulty sleeping,
signs of
malaise,
megaloblastic
confusion
anemia, fatigue,
weakness,
dyspnea before
SKIN- rash
and throughout
the therapy

Name of Drug

Classification:

Action &
Indication
INDICATION

Mineral and
electrolyte
replacements/

- Treatment and
prevention of
hypocalcemia

suppements

- Maybe used as
antacids

- CaCO3
500mg/tab TID

Adverse Effects

Nursing
Responsibilities

GI- constipation,

- Observe 12 Rights
in medication
administration
Nausea, vomiting
GU- calculi,
hypercalcemia

-Observe patient for

symptoms of
hypocalcemia
-Monitor serum
calcium, ionized
calcium

Mechanism of
action
- Essential for
nervous
Muscular and
Skeletal system
- maintain
capillary
membrane and

Capillary
permeability
Act as an
activator in the
transmission of
Nerve impulses
and contraction
of cardiac,
skeletal, smooth
muscle

Name of Drug

Classification:

Action &
Indication
INDICATION

Antigout agents - Prevention of

attack of gouty
arthritis and
Antihyperuricemi

Adverse Effects

Nursing
Responsibilities

CV- Hypotension, - Observe 12 Rights

flushing
in medication
hypertension,
administration
bradycardia and
heart failure
-Monitor Intake and

nephropathy

dosage

- Allopurinol
100mg/tab

Mechanism of
action
Inhibits the
production of
uric acid by
inhibiting the
action of
xanthine
oxidase
- lowering of
serum uric acid
levels

CNS- drowsiness

output

GI- diarrhea,
hepatitis, nausea
and vomiting

- Assess patient for

rash or severe
hypersensitivity
reactions

GU- renal failure,

hematuria

- Monitor for joint

pain and swelling

Name of Drug

Classification:

Action &
Indication
INDICATION

Antianemics

- Treatment of iron
deficiency in
patients
Iron Supplements
undergoing
chronic
hemodialysis or
peritoneal
- Ferrous
sulfate
dialysis who are
tab 1 tab OD
currently
receiving
erythropoietin

Adverse Effects

CNS- dizziness,
headache
symptoms
CV- hypotension,
hypertension,
tachycardia
GI- nausea,
constipation
dark stool

Nursing
Responsibilities
- Observe 12 Rights
in medication
administration
-Assess nutritional
status and
dietary history to
determine possible
causes of anemia
-Assess bowel
function for
constipation or
diarrhea

diarrhea

Mechanism of
action
- An essential
mineral found in
hemoglobin,
myoglobin and a
number of
enzymes

epigastric pain

- Monitor
hemoglobin level

Name of Drug

Classification:

Action &
Indication
INDICATION

Antigout agents - Prevention of

attack of gouty
arthritis and
Antihyperurecemi
nephropathy
cs

- Allopurinol
100mg/tab

Mechanism of
action
Inhibits the
production of
uric acid by
inhibiting the
action of
xanthine
oxidase
- lowering of
serum uric acid
levels

Adverse Effects

Nursing
Responsibilities

CV- Hypotension, - Observe 12 Rights

flushing
in medication
hypertension,
administration
bradycardia and
heart failure
-Monitor Intake and
output
CNS- drowsiness
- Assess patient for
GI- diarrhea,
rash or severe
hepatitis, nausea
hypersensitivity
and vomiting
reactions
GU- renal failure,
hematuria

- Monitor for joint

pain and swelling

Name of Drug

Action &
Indication

Classification:

INDICATION

Epoetin alpha

- Management of
anemia caused
by Chronic renal
Disease

- Erythropoetin
4000 units 2x a
week
Mechanism of
action
- Stimulates the
bone marrow to
enhance the
rate of red

Adverse Effects

Nursing
Responsibilities

CNS- headache,
seizures,

- Monitor BP before
the therapy
(160/80mmHg),
Blood pressure
Dizziness,
may increase
especially when
fatigue
hematocrit is
increasing in the
CV- hypertension,
early part of the
therapy
edema
GI- nausea,
vomiting
Respiratorycough shortness

- Patient treated with

Epoetin alpha may
need additional
heparin to prevent
clotting during

blood cells,
decreases the
need of blood
tranfusions

of breath
SKIN- rash

dialysis treatment
- Advice the patient
to control BP by
strict adherence
of diet regimen
and drug therapy
- Give supplemental
iron to enhance
effect
- Avoid shaking( will
denature the
glycoprotein
making it
biological
inactive)

Name of Drug

Classification:

Action &
Indication
INDICATION

Adverse Effects

Nursing
Responsibilities

Headache,
- Observe 12 rights
palpitation, lower

Calcium channel- Hypertension,

blockers
angina pectoris
and vasopastic
angina
- Nifedipine
30mg/tablet TID
- Nicardipine
10mg/amp

Mechanism of
action
- Inhibits the
transport of
calcium into
myocardial and
vascular smooth
muscle cells,
resulting in
inhibition of
excitationcontraction
coupling and
subsequent
contraction

leg edema,
- Monitor Blood
hypotension,
pressure regularly,
dizziness, GI
especially in
disturbances and
patient who take
muscle cramps
beta blockers or
hypertensives
- Tell patient to
protect capsules
from direct
moisture and to
store at room
temperature
- Care must be
exercised in
patients with very
low bp(,90 mmHg
systolic pressure)

Name of drug

Ciprofloxacin
Classification:
Broad Spectrum
antibiotic
Dosage &
Frequency:
Ciprofloxain
500mg/tab

Action &
Indication

-Inhibits DNA
gyrase
-Bactericidal
effect
-Pseudomonas
infection, gram
negative urinary
tract infection or
gram negative
systemic
infection

Adverse Effects

CNS dizziness,
headache,
insomnia,
confusion
GI- nausea and
vomiting,
diarrhea,
flatulence
DERMA- elevated
BUN,SGPT,SGOT,
creatinine,
decrease WBC,
HCT

Nursing
Responsibilities
&
Considerations
-Administer with
caution on the 12
rights in
medication
administration
-Monitor water
intake to prevent
crystallization
-Do not give with
antacids
-Give within 2
hours after meals
-Monitor for
rashes