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REVIEW SHEET

EXERCISE
NAME_________________
________________
LAB TIME/DATE
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E
n
d
o
cr
in
e
S

yst
em
Ph
ysi
olo
gy

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___________________
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1.Matcheachofthehormonesinthelefthandcolumnwithitssource.
_
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2. Each
__
_
hormone is_
__
known to_
__
have a
__
_
specific
__
_
target
__
_
tissue. For
__
each of the_
__
following _
__
hormones, _
__
list its_
targettissue_
__
and
__
_
describe its_
__
specific
__
_
action.
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_
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_
thyroxine _
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_________ _
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_________ _
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_________ _
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_________ _
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_________ _
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_________ _
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_________ _
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_________ _
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_________ _
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estrogen
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_
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_
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_________ _
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_________ _
_________ _
_________
insulin

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_
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________
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________
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________
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________
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________
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________
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________
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_
_
follicle
stimulating _
hormone _
_
(FSH)
_
_________
_________
_________
_________
_________
_________
_________
_________
_________

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3. Whatistheroleofthe

hypothalamus in the
productionofthyroxine
andTSH?

4. How does thyrotropin

releasing hormone
(TRH) travel from the
hypothalamus to the
pituitarygland?
5
9

60

Review Sheet 4

5. Whataretropichormones?

6. Inthemetabolismexperiment,whatwastheeffectofthyroxineontheoverallmetabolicrateoftheanimals?

7. Usingtherespirometermanometer,youobservedtheamountofoxygenbeingusedbyanimalsinaclosedchamber.What
happenedtothecarbondioxidetheanimalsproducedwhileinthechamber?

8. (a)Iftheexperimentalanimalsinthechamberwereengagedinphysicalactivity(suchasrunninginawheel),howwould
thischangetheresultsofthemetabolismexperiment?

(b)Whatchangeswouldyouexpecttoseeinfluidlevelsofthemanometer?

9. Why didnt the administration of thyroid stimulating hormone (TSH) have any effect on the metabolic rate of the
thyroidectomizedrat?

10. Whydidnttheadministrationofpropylthiouracilhaveanyeffectonthemetabolicrateofeitherthethyroidectomizedrat
orthehypophysectomizedrat?

11.Explainwhyovariectomizedratswereusedinthis
experimentandcorrelatethistotheirbaselineTscore.

Review Sheet 4

12. Recapyourpredictionsregardingtheeffectsofcalcitoninandestrogenonbonedensityandexplainwhyyoumadethose
predictions.

13. Whywasoneoftheovariectomizedratsinjectedwithsaline?

14. Whateffectdidtheadministrationofestrogeninjectionshaveontheestrogentreatedrat?

15. Whateffectdidtheadministrationofcalcitonininjectionshaveonthecalcitonintreatedrat?

16. Howdidyourresultscomparetoyourpredictions?

17. Whatisaglucosestandardcurve,andwhydidyouneedtoobtainoneforthisexperiment?

18. Whichpatient(s)hadglucosereading(s)inthenormalrange?

19. Whichpatient(s)hadglucosereading(s)inthediabeticrange?

62

Review Sheet 4

20. Whichpatient(s)hadglucosereading(s)intheimpairedrange?

21. DescribethediagnosisforPatient3.

22. WhichpatientwouldmostlikelybediagnosedwithCushingsdisease?Why?

23. WhichtwopatientshavehormonelevelscharacteristicofCushingssyndrome?

24. Patient2isbeingtreatedforrheumatoidarthritiswithprednisone.Howdoesthischangethediagnosis?

25. WhichpatientwouldmostlikelybediagnosedwithAddisonsdisease?Why?

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