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11/22/2015

DifferencesbetweenDNAandRNA

DifferencesbetweenDNAandRNA
PostedbySagarAryal

August14,2015

DifferencesbetweenDNAandRNA
Hereare17differencesbetweenDNAandRNA.

S.N.

DNA

RNA

1.

DNAstandsforDeoxyribonucleicAcid.
ThesugarportionofDNAis2
Deoxyribose.

RNAstandsforRibonucleicAcid.Thesugar
portionofRNAisRibose.

2.

ThehelixgeometryofDNAisofBForm
(AorZalsopresent).

ThehelixgeometryofRNAisofAForm.

DNAisadoublestrandedmolecule

RNAusuallyisasinglestrandhelix

3.

http://www.microbiologyinfo.com/differencesbetweendnaandrna/

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11/22/2015

DifferencesbetweenDNAandRNA

consistingofalongchainofnucleotides.

consistingofshorterchainsofnucleotides.

4.

ThebasespresentinDNAareadenine,
guanine,cytosineandthymine.

ThebasespresentinRNAareadenine,
guanine,cytosineanduracil.

5.

DNAisselfreplicating.

RNAissynthesizedfromDNAonanas
neededbasis.

6.

BasePairing:AT(adenine
thymine)GC(guaninecytosine).

BasePairing:AU(adenineuracil)GC
(guaninecytosine).

7.

PurineandPyrimidinebasesareequalin
number.

Thereisnoproportionalityinbetweenthe
numberofPurineandPyrimidinebases.

8.

DNAissusceptibletoUVdamage.

ComparedwithDNA,RNAisrelatively
resistanttoUVdamage.

9.

Hydrogenbondsareformedbetween
complementarynitrogenbasesofthe
oppositestrands(AT,CG).

Basepairingthroughhydrogenbonds,
occursinthecoiledparts.

10.

DNAisfoundinthenucleusofacelland
inmitochondria.

DependingonthetypeofRNA,thismolecule
isfoundinacellsnucleus,itscytoplasm,
anditsribosome.

11.

DNAcantleavethenucleus.

RNAleavesthenucleus(mRNA).

12.

TheCHbondsinDNAmakeitfairly
stable,plusthebodydestroysenzymes
thatwouldattackDNA.Thesmallgrooves
inthehelixalsoserveasprotection,
providingminimalspaceforenzymesto
attach.

TheOHbondintheriboseofRNAmakes
themoleculemorereactive,comparedwith
DNA.RNAisnotstableunderalkaline
conditions,plusthelargegroovesinthe
moleculemakeitsusceptibletoenzyme
attack.

13.

Renaturationaftermeltingisslow.

Itisquitefast.

14.

DNAisonlytwotypes:intranuclearand
extranuclear.

ThreedifferenttypesofRNA:mRNA,tRNA
andrRNA.

15.

Itsquantityisfixedforcell.

ThequantityofRNAofacellisvariable.

16.

Itislonglived.

SomeRNAsareveryshortlivedwhileothers
havesomewhatlongerlife.
Functions:Usedtotransferthegenetic

http://www.microbiologyinfo.com/differencesbetweendnaandrna/

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DifferencesbetweenDNAandRNA

17.

Functions:Longtermstorageofgenetic
informationtransmissionofgenetic

codefromthenucleustotheribosomesto
makeproteins.RNAisusedtotransmit

informationtomakeothercellsandnew
organisms.

geneticinformationinsomeorganismsand
mayhavebeenthemoleculeusedtostore
geneticblueprintsinprimitiveorganisms.

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ABOUTTHEAUTHOR
SagarAryal
IamSagarAryal,apassionateMicrobiologistandtheScientificBlogger.Iamcurrentlyinvolvedin
myMaster'sDegree(Microbiology)ThesisandworkingasatraineeatSt.Xavier'sCollege,
Kathmandu,Nepal.IamparticularlyinterestedinresearchrelatedtoMedicalMicrobiologyand
Virology.FindmeonFacebook,TwitterorLinkedin!!!

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