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PhysiomeWikipedia,thefreeencyclopedia
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Thephysiomeofanindividual'sorspecies'physiologicalstateisthedescriptionof
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itsfunctionalbehavior.Thephysiomedescribesthephysiologicaldynamicsofthe
normalintactorganismandisbuiltuponinformationandstructure
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(genome,proteome,andmorphome).Thetermcomesfrom"physio"(nature)and
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"ome"(asawhole).
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Initsbroadestterms,itshoulddefinerelationshipsfromgenometoorganismand
fromfunctionalbehaviortogeneregulation.InthecontextoftheIUPSPhysiome
Project,itincludesintegratedmodelsofcomponentsoforganisms,suchas
Tools
Whatlinkshere
particularorgansorcellsystems,biochemical,orendocrinesystems.
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TheIUPSPhysiomeProjectisaworldwideefforttodefinethephysiomethroughthe
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developmentofdatabasesandmodelswhichwillfacilitatetheunderstandingofthe
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integrativefunctionofcells,organs,andorganisms.Theprojectisfocusedon
compilingandprovidingacentralrepositoryofdatabases,linkingexperimental
Wikidataitem
informationandcomputationalmodelsfrommanylaboratoriesintoasingle,self
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consistentframework.Thiscoalescenceofresearcheffortwillpromote
comprehensivedatabasesandanintegrative,analyticalapproachtothestudy
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ofmedicineandphysiology.
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TheconceptofaphysiomeprojectwaspresentedtotheInternationalUnionof
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PhysiologicalSciences(IUPS)byitsCommissiononBioengineeringinPhysiologyin
1993.AworkshopondesigningthePhysiomeProjectwasheldin1997.Atitsworld
congressin2001,theIUPSdesignatedtheprojectasamajorfocusforthenext
decade.[1]TheprojectisledbythePhysiomeCommissionoftheIUPS.[2]
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Otherresearchinitiativesrelatedtothephysiomeinclude:
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TheEuroPhysiomeInitiative
TheNSRPhysiomeProjectoftheNationalSimulationResource(NSR)at
theUniversityofWashington,supportingtheIUPSPhysiomeProject
TheWellcomeTrustHeartPhysiomeProject,acollaborationbetween
theUniversityofAucklandandtheUniversityofOxford,partofthewiderIUPS
PhysiomeProject
https://en.wikipedia.org/wiki/Physiome
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7/3/2016
PhysiomeWikipedia,thefreeencyclopedia
Seealso
[ edit ]
Physiomics
LivingHumanProject
VirtualPhysiologicalHuman
VirtualPhysiologicalRat
Cytome
HumanGenomeProject
Listofomicstopicsinbiology
Cardiophysics
References
[ edit ]
1.^Hunter,PeterJ.ThomasK.Borg(March2003)."Integrationfromproteinstoorgans:
thePhysiomeProject".Naturereviews.Molecularcellbiology4(3):pp.237
243.doi:10.1038/nrm1054
.PMID12612642
2.^"WelcometotheNSRPhysiomeProject" .NSRPhysiomeProject.28October
2008.Retrieved13December2008.
Externallinks
[ edit ]
IUPSPhysiomeProject
NSRPhysiomeProject
NationalResourceforCellAnalysisandModeling(NRCAM)
Categories: Physiology
Biophysics
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