THE PORPHYRIAS

Acute Intermittent Porphyria

Deficiency: Phorphobilinogen deaminase
Increased: Porphobilinogen and ALA
Congenital Erythropoietic Porphyria
Deficiency: Uroporphyrinogen III Synthase
Increased: Uroporphyrin I and Coproporphyrinogen I
Porphyria Cutanea Tarda
Deficiency: Uroporphyrinogen decarboxylase
Increased: Uroporphyrin
Hereditary Coproporphyria
Deficiency: Coproporphyrinogen oxidase
Increased: Coproporphyrinogen
Varigate Porphyria
Deficiency: Protoporphyrinogen Oxidase
Increased: Protoporphyrinogen IX and prior
intermediates
Erythropoietic Protoporphyria
Deficiency: Ferrochelatase
Increased: Protoporphyrin