ABSTRACT

The Relationship beetween Obstructive Sleep Apnea (OSA) in Acute Ischemic Stroke Patients
and Clinical Outcomes based on The National Institutes of Health Stroke Scale (NIHHSS)
Rilia Datan SP1, Audry Devisanty Wuysang2
1 Resident of Neurologist Education Program Medical Faculty Hasanuddin University, Makassar, Indonesia
2 Lecturer of Neurologist Education Program Medical Faculty Hasanuddin University, Makassar, Indonesia

Background More than 50% of stroke patients have sleep-disordered breathing, mostly in the form of
obstructive sleep apnea. The presence of OSA has been associated with long-term outcomes are worse and
increased long-term stroke mortality. This study aims to determine the relationship between OSA in acute
ischemic stroke patients and clinical outcomes based on The National Institutes of Health Stroke Scale
(NIHSS)
Methods The design of this study was a comparative cross-sectional, that was perform from 1 st June to 15th
August 2016 in Hasanuddin University Teaching Hospital and satellites. Sample consist of 25 hospitalized
patients with acute ischemic stroke onset 1 st to 3rd day. We measure the degree of OSA using the Berlin
questionnaire test.
Results OSA group consist of 7 sample (4 male, 3 women) and control consist of 18 sample (10 male, 8
female). This study showed significance of clinical outcomes from OSA group p=0.016 vs control (non
OSA) group p=0,000 used Wilcoxon rank test. Velocity NIHSS for 7days for OSA group was -27.5541 vs
control group -28.8973 used T-Test.
Conclusion Clinical outcomes OSA group (p=0,016) are worse than controls (p = 0.000), with velocity
NIHSS for 7 days for OSA group slower were -27.5541 vs control -28.8973
Keyword OSA, acute ischemic stroke, NIHSS