Why
W G
Gout D
Does N
Not
Ha
appen
n to Most
M OOther
M
Mamm als?

 
  
 

• Whhenever it coomes to discu ussing about gout related

iss
sues, one prim
mary topic is, "What
" causes gout?".

• Th
hen people will
w nting fingers at the overr
start poin
consumption of high purine fo
oods such as organs meat,
sardine, anchov
vies, mushroomms and the lis
st goes on.

 
  
 

urine is a natu
• Pu ural organic co
ompound exists in all living
thiings. The am
mount of naturally occurrin ng purines on
earth is enormous. Out of fourf bases foound in DNA:
denine, cytosin
ad ne, guanine, and thymine two of them
(addenine and gu
uanine) are foorms of purine
e.

• Otther popular forms of purrine are caffe

eine found in
coffee and the eobromine (the compoundd that givess
chocolate its bittter taste).

 
  
 

very day there

• Ev e are millions of body cells die, and this
s
will result in hu
uge amount ofo DNA being broken down
to release thosee DNA bases.

uanine will go
• Gu o through a process
p called deamination
wh
hich break do own guanine tot xanthine b by an enzyme e
called guanase, then anotherr enzyme, xan nthine oxidase
e
will then oxidize
e xanthine to uric
u acid.

 
  
 

• Urric acid is the final end prod

ducts of purine
e degradation
in humans and higher ap pes, but the degradation
proocess goes on ne step furtheer in most oth
her mammals.
Thhere is anothe er enzyme ca alled uricase w
which furtherr
tra
ansforms uric acid to allanto oin.

• Dooes that name e sound famiiliar to you? AAllantoin is a

po
opular ingredient found in a wide rang ge of beauty y
pro
oducts! Take a look at the ingredients list of some off
the
e facial cream
ms.

 
  
 

cientists believ
• Sc ve that uricasse did exist in
n our ancientt
an
ncestors, but somehow
s alon
ng the processs of evolution,
hu
uman lost the e ability to produce uricasee in the body y
du
ue to some sorrt of enzymatiic defects.

his could be what

• Th w the factor to that is re
esponsible forr
all types of goutt, primary as well as second dary.

 
  
 

nce purine orr uric acid do

• Sin oes not occurr in excessivee
am
mount inside most
m mammal body, why w we, human gett
a huge surge off uric acid in our blood afteer consuming
e meat from these
the t animals, especially th
heir organs?

• Whhy for some gout

g patients, consumption of just small
pie
ece of these m
meats will sufffer the gout attack within
ho
ours?

 
  
 

wo major animal orga

• Tw ans that c contain high
concentration off purine are th
he liver and k
kidney. This is
s
ecause that is
be s where the purine
p degradation process s
tak
kes place.

• Huuge amount of purines will be carried by

y the blood to
o
theese sites to be
b broken do own to uric a
acid and then
allantoin which will eventually get out from its body y
thrrough the urin
ne of feces.

 
  
 

"Annd now I would

w like
e to invite
e you to
claim your Free
F Instaant Accesss to one
of my co omprehen nsive repoorts
on Common
C G
Gout Treaatments w when you
vis
sit http:///www.say yonaragou ut.net.”