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Fibrosis

Asthma

Emphysema

Cause

Allergy

1-Smoking

-1)infection eg
turberculosis

1)Dust

2-AIR POLLUTION

2)Pollen
-2)Asbestos
-3)dust
1-The scar tissue
around the epithelia of
the alveoli thickens the
epithelium and causes
cavities ,(holes).
2-This increases the
diffusion pathway .
3-There is also some
loss of elastin so there
is Less recoil and

1-Histamine released by 1-The elastin around


white blood cells.
the alveoli is destroyed.
2-Inflames the airways
And constricts the
bronchioles.

2-The alveoli have no


recoil.
Less air exhaled

3-Mucus secreted by
goblet cells blocks the
airways even more

3-This results in a lower


surface area,
The alveoli are
enlarged.

5-Less air exhaled.


Symptoms

This results in
Difficulty
Shortness of
breathing
breath
Wheezing.
Fatigue weakness
tight chest
Faster breathing
coughing
rate so more ATP
needed
Dry cough
(mucus not
produce

shortness of
breath because
less oxygen
chronic cough
tierdness

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