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Tips - MCQ 2549 PDF
Tips - MCQ 2549 PDF
PQ 191 Rx CU 65 et al.
1.
2.
3.
4.
**
MCQ (
MCQ OSPE) **
4 A,B,C,D (
1
()
case
:
:
4:3:3 ( 2551)
()
..
- , , , (), (),
( ), , , New Light
(), (USA)
5
-
2549
( 1)
1
:
1.
a. ( tuberculosis)
b. (pneumonia)
c. (gonorrhoea)
d. (candidosis)
e. ( HIV)
2.
a. Abacavir
b. Ritonavir
c. Nevirapine
d. Lamivudine
e. Diravirdine
6.
a. Cotrimazole
b. Nystatin
c. Claritromycin
7.
rifampicin
3. GPOvir
a. Zidovudine + Didanosine +
1. zidovudine
Ritronavir
b. Stavudine + Lamivudine +
Saquinavir
c. Stavudine + Lamivudine
+Nevirapine
4.
3.azithromycin
5.
lipodystrophy
4. rifampicin
2. ritonavir
zidovudine
8.
a.
b.
c.
e.
d.
11.
c. Gonorrhea
9. Ritronavir
b.
....
c.
d. Herpes genitalis
e. Trichomoniasis
12.
a. Tinidazole
single dose
basic functionality
b. Metronidazole
ionize
e.
single dose
polar functionality
c. Clotrimazole
10. Rifampin
d. Ciprofloxacin
e. Cotrimoxazole
a. air oxidation
hydrozone
c.
d.
e.
2 24
b. hydrolysis
peptide-like ...
d.
a. Bacterial vaginosis
b. Candidiasis
a.
13.
a. Tetracyclin 250
mg
b.
3
c.
d.
e.
14.
e.
19.
a.
b.
c. 8-15
a. Case control
d.
e. 2g
15.
c. Case
d. Emulsion base
Vanotab
e. Absorption base
16.
a. Clotrimazole
b. Cotrimoxazole
c. Itraconazole
17.
18.
d. Metronidazole
a.
2x2pc 1
20
70%
90%
Vanotab
1 OD 1
b.
a. 90
d.
c. 100
c.
b. 98
d. 103
b. Diazepam
e. 110
c. Vigabutrin
3 32
d. Carbamazepine
e. Gabapentin
23.
Phenytoin
a. Glugival hyperplasia
c. Rash
3 capsule hs
b. Hepatitis
d. Ataxia
Phenytoin
28 mg/L (
Phenytoin
10-20 mg/L)
21.
a.
b.
c.
d.
..
e.
2
22.
Phenytoin Sodium
a. Ethosuximide
24.
e. Hyponatremia
a. Phenytoin
b. Valproate
c. Phenobarbital
d. Carbamazepine
25.
phenytoin phenytoin
a. Erythromycin
b. Cimetidine
c. Conjugated estrogen
26. phenytoin
a. Lactose
b. Dextrose
c. Calcium sulfate
d. Pregelatinized starch
e. Microcrystalline cellulose
27.
phenytoin
a. Crospovidone
b. Croscarmellose
b.
c.
d.
e.
4 50
Non-Small Cell
1 hour on day 1
28.
29. phenytoin
d. ultraviolet spectrometry
(UV) Benzene
e. ultraviolet spectrometry
60 kg. 180 cm
2
a. 150
b. 175
c. 200
d. 225
e. 250
(UV) secondary
amide
30.
......2540
Phenytoin
a.
32.
Acute Emetic
a. Ondansetron
b. Dexamethasone
c. Metoclopramide
d. Ondansetron +
48 hours
e. Metoclopramide +
8 hours
Dexamethasone
Dexamethasone
Cisplatin
33.
a. Akylating agent
2 hours
d. Intercalating agent
time to precipitation
e. Inhibitor of mitosis
etoposide
34. Cisplatin
(Nephrotoxicity)
(100 mg/m )
D5W 500 ml
a.
a. 96 .
b. 48 .
b.
Magnesium
c. 8 .
c. Osmotic diuretic
d. 2 .
Mannitol
e.
d. Cisplatin
Sodium chloride
35. etoposide
stability
At temperature in D5W or NS in
polyvinyl
hours
b. Topoisomerase II inhibitor
c. Antimetabolite
0.2 mg/ml
96
36.
a.
b.
.....
c.
d.
a. A hydrophobic
medium
e. ()
b. B hydrophilic medium
c. C hydrophobic
medium
37. Cisplatin
d. B
a. Doxorubicin
e. C
b. Cytarabine
c. Melphalan
40.
d. Carboplatin
+
++
++
+ +
+- +
+ +
- -+ - +
-+
+ +
hood
a. Diffusion controlled
b. Dissolution controlled
c. Erosion controlled
d. Osmotic controlled
e. Ion exchange controlled
39.
e. Metrotrexate
38.
5
3-4
BP 138/88 mmHg HR 85 RR
18/min
Total cholesterol (<240)
mg/dL
243
Triglyceride (<200)
200 mg/dL
HDL- C (>40)
33mg/dL
FBS (<126)
135 mg%
HbA1c (<7)
7.0%
Myocardial infarction 53
44
Glibencarmide 10 mg BID
41. LDL- C
a. 130 mg/dl
b. 140 mg/dl
c. 150 mg/dl
d. 160 mg/dl
e. 170 mg/dl
42. major risk factor
a.
Myocardial infarction
53
b.
Myocardial infarction
44
c.
d.
HDL-C 33 mg/dl
e.
53
43.
Hyperlipidemia
a. Total cholesterol
b. Triglyceride
c. HDL-C
d. LDL-C
e. Non-HDL-C
44. LDL
C
atherosclerosis
a.
a. Statin
e. plant sterols
sitosterol campesterol
a. LDL-C receptor
b. cholesterol
LDL-C receptor
c. enterohepatic recycling
cholesterol
d. VLDL
e. HDL
lactone ring
carboxylic acid
d. Simvastatin
Simvastatin
Pravastatin
47.
a. Cholestyramine
Simvastatin Simvastatin
lactone ring
b. Cholestyramine
Pravastatin Pravastatin
carboxylic acid
c. Simvastatin
Cholestyramine
d. Cholestyramine
Simvastatin
Provastatin
e. Cholestyramine
Simvastatin Provastatin
48.
a. Pravastatin prodrug
b. Simvastatin Pravastatin
prodrug
c. Pravastatin
2
lactone ring
e. Simvastatin Pravastatin
prodrug
49.
a.
b.
c.
d. ...
e.
50.
statin ....
sectional study
d. Meta-analysis, Randomized
controlled study
e. Cross-sectional study,
c.
6 25
10
Salbutamol MDI
d.
e.
51.
a.
b.
bioavailability
54. 2
a. Inhaled fenoterol (100mcg/puff)
3 puffs
Zileuton (600mg/tablet)
b.
c.
d.
1 4
c. Sustained-released theophylline
(200mg) 1 2
e.
52.
a.
b.
c.
d.
e.
d.
mcg/puff) 2 puffs 2
e. Ketotifen (1mg/tablet) 1
2
55.
53. Salbutamol
MDI
a. long-acting beta 2
antagonist
b.
inhaled steroid
steroid
mcg/blister) 1 blister
12 .
b.
(1mg/puff) 2 puff 3
mcg/inhalation) 2
inhalation 3
Prednisolone (5 mg/tab)
d.
mcg/puff) 2 puff 3
56.
steroid
a. Sore throat
b. Pharyngitis
c. Metallic taste
d. Gingivitis
e. Oral thrush
57.
Theophylline
a. Ciprofloxacin
b. Fluvexamine
c. Cimetidine
d. Amoxicillin
e. Rifampicin
a. spacer
Metered Dose
Inhaler (MDI)
oral
thrash
b.
Nebulizer
(DPI) ...
10
d. breath activated
device
e. Turbuhaler
59.
a. Turbutaline (2.5mg/tab)
b. Prednisolone (5mg/tab)
c. Inhaled fermoterol (4.5
mcg/dose)
e. Theophylline (200 mg
sustained-release)
60. Evohaler
b. propellant
c.
c. propellant non-CFC
d. 1
d.
e.
7 33
e.
64.
a.
b.
c.
d.
61.
a. Prednisolone
e.
65.
a. Senna
b. Hydrocortisone, cimetidine
b. Castor oil
c. Bisacodyl
62.
d. Lactulose
a. Senna
b. Castor oil
c. Bisacodyl
d. Mineral oil
e. Phylium seed
63.
a. 6
b.
66.
e. Phylium seed
a.
b.
c.
d.
e.
15
67.
2g
0.3g Displacement
a. 155 g
b. 175 g
c. 180 g
d. 197 g
e. 200 g
68.
15
a. Calcium carbonate
b. Potassium chloride
c. Sodium bicarbonate
d. Potassium lichromate
e. Potassium permanganate
69.
.....
15 3
a.
b.
c.
d.
e.
70.
a.
b.
c.
d.
e.
8 60
48 kg 170 cm
c. Furosemide
d. Amiloride
e. Indapamide
74.
a.
c.
5 creatinine
d. -
clearance 18 ml/min
e.
71.
Creatinine clearance
acidosis
b. Renal insufficiency
c. Chronic renal failure
d. Uremia
hyperkalemia
a. Potassium chloride
b. Sodium chloride
d. Calcium chloride
e. Calcium phosphate
73.
a. Hydrochlorothiazide
b. Spironolactone
75.
sodium
bicarbonate
sodium bicarbonate
5 ml 2 mg/ml
a. 2 Amp
b. 3 Amp
c. 4 Amp
d. 5 Amp
e. 6 Amp
79. A
76.
diuretic .......
HCTZ
a. Case control
b. Cohort
studies
a. Sterility
d. Deseriptive
b. Osmolarity
80.
a.
e. Preservative
b.
78.
Sodium bicarbonate
c.
e.
d.
injection
a.
b.
50,000
c.
d.
50,000
e.
81.
a. Lithium carvonate
b. Clozapine
c. Chlorpromazine
d. Haloperidol
e. Diazepam
b. Elomipramine
82. fluoxetine
c. Amitriptyline
a.
d. Doxepin
b.
c.
d.
....
e.
83.
major depressive disorder
e. Sertraline
85. antidepressant
a.
b.
2-3
c.
d.
a. Venlafaxine
b. Paroxetine
c. Amitriptyline
d. Bupropion
e. Sertraline
84.
a. Imipramine
e.
86.
benzodiazepine
a.
b. Triazolam
25%
c. Olanzapine
75%
89.
a. matrix
b. osmotic
d.
c.
25%
e.
1
87.
d. matrix
90.
( bulking agent)
( disintegrant )
a. Lactose
b. Magnesium sulfate
c. Microcrystalline cellulose
a.
d. Corn starch
b.
c.
d.
e.
88. Risperidone
methanol
a. Shellac
methylcellulose
91.
Thyroxine
decreased appetite
2
1
cuthyroidal state
92. Propylthiouracil
2542
a.
b.
methimazole
b.
Propylthiouracil
c.
d.
iodine
e. propranolol
propylthiouracil
94.
thiouracil
a.
b.
c.
95. Propylthiouracil
b. thyroid
c.
d.
e.
93.
a. Propylthiouracil
a. thiourea
hormone
c.
hypothyroid
d. thyroid
peroxidase
e. T3
96. Propylthiouracil: White, crystalline
... 50 mg
conjagation carbimazole
d.
amide
hydrolysis
methimazole
carbimazole
e.
ester hydrolysis
carbimazole
carbimazole
97. propanolol
propylthiouracil
a. Propanolol alpha-
p
ropylthiouracil
methimazole,
carbimazole propylthiouracil
a. methimazole, carbimazole
propylthiouracil
metabolized
desulfunation
b. propylthiouracil
metabolized
dealkylation Propyl
group
c. methimazole
metabolized
b. Propanolol
tremor tarchycardia
thyrotoxicosis
c. Propanolol
pharmacokinetic
propylthiouracil
propylthiouracil
d. Propanolol
propylthiouracil
e. Propanolol
propylthiouracil
T4
98. goiter
a. Ion thiocyanate
goiter
b. Thiocyanate
metabolize ...
c. Lithium secretion
Thyroxine
thiiodothyroxine
hyperthyroidism
e. Propylthiouracil
11 55
estradiol
a.
d. Goitrin thyroid
peroxidase
b.
e. Percholate ion
uptake iodide
c.
iodide thyroid
d.
a.
iodine
e.
b. iodine
c.
d.
e. thiocyanide
100.
Lugols solution
a. Iodine + KI
b. Manganese
c. Methimazole
d. Thiocyanate
102.
(transdermal patch)
a. first
pass metabolism
b.
c.
d.
d.
partition
e.
osteoperosis
103.
coefficient 1
e. therapeutic index
a. estradiol valerate 2 mg +
norgestrel 0.5 mg
b. medroxyprogesterone acetate
5 mg
106.
a.
c. ethimylestradiol 30 mcg +
b.
cypoterone acetate 2 mg
c.
d.
mg
e.
spectrum
107.
phytoestrogen
103
a. Hyperlipidemia
b. Osteoperosis
c. Hyperbilirubinemia
d. Congestive heart failure
a. UV-visible spectrophotometer
e. Thromboembolism
105.
b.
c.
Transdermal
b.
c.
H-NMR spectrometer
13
C-NMR spectrometer
d. FT-IR spectro
a.
e. Mass spectrometer
108.
a. B1-6-12 tablet
b. Doxycyclin capsule
c. Senna tablet
d. Antacid gel
SLE
a.
e. Premarin 0.625 mg
109.
111.
hydrazine
Lupus
b. sunscreen SPF 15
a. Ibuprofen 400 mg
c.
b. Dexamethasone 0.5 mg
c. Indomethazin 25 mg
d.
d. Piroxicam 10 mg
hydralazine chorpropamide
e. Celebrex 200 mg
110.
anticonvulsant
lupus
e.
a. Diazepam 10 mg
b. Diclofenac inj 75 mg
c. Methadone tab 10 mg
d. Pentazocine tab 25 mg
a. Hydrocarbon base
b. Oleaginous base
12 22
c. Absorption base
2
Systemic Lupus
Erythematosus (SLE)
112.
113.
Topical steroid
a. Psuedoplastic flow
b. Psuedoplastic flow with
thixotropy
c. Product C
thixotropy
d.
d. Antithixotropy
e.
e. Newtonium flow
SLE
116.
(rate
hydroxychloroquin 200 mg
114.
a. (slope)
b.
(slope)
a. Ocular examination
c. Intercept
b. Chest x-ray
d. Intercept
e. Intercept slope
d. Urinalysis
e. EKG
aspirin
117.
aspirin tab
a. (half life)
115.
aspirin
aspirin tab
b. (shelf life)
c. . aspirin
aspirin
aspirin
Product A
d. . aspirin
Product B
Product C
e. aspirin
Aspirin tab
a. Product A
b. Product B
118.
steroid cytotoxic
drug
TB
Isoniazid,
Rifampin, Pyrazinamide,
e.
Ethambutol
SLE
a. Isoniazid
120.
amcinonide
prednisolone
b. Rifampin
c. Pyrazinamide
d. Ethambutol
e. Pyrazinamide
amcinonide
Ethambutol
119.
Prednisolone
Dexamethasone
a. Dexamethasone
steroid
b. Dexamethasone
steroid
c. equivalent dose
Potency
d.
Prednisolone
glucocorticoid
dexamethasone
mineralocorticoid
prednisolone
a.
Pregnane
b. Amcinonide antiinflamatory
activity prednisolone
c. Amcinonide lipophilicity
prednisolone
retention prednisolone
e. Amcinonide
9-F 11-OH
amcinonide glucocorticoid
activity prednisolone
13 45
1
paracetamol
121.
e. Tramadol
125.
a. Corticosteroid
a. Rheumatoid arthritis
c. Uricosuric agent
b. Osteoarthritis
d. NSAID
c. Osteoporosis
d. Acute gout
e. Osteomalacia
122.
a. Paracetamol
b. Probenacid
c. Colchicine
d. Tramadol
e. Allopurinol
123.
e. Para-aminophenol derivatives
126.
Rx
% labeled amount
60
. .. 2510
a.
b.
c.
a.
d.
b.
127.
c. Efervessant tablet
b. Indomethacin
c. Allopurinol
d. Paracetamol
a. Prednisolone
e.
a. Uncoated tablet
e.
124.
Diclofenac 25 mg # 30
d.
c.
a.
b.
b. Staphylococcus epidermidis
c.
c. Streptococcus pnuemoniae
e.
e. Chlamydia tracamatis
d.
129.
d. Neisseria gonorrheae
132.
a. Celecoxib
b. Tramadol
c. Meloxicam
d. Prednisolone
130.
133.
b.
c. RNA
a.
d. leucocytes
b.
d.
2
134.
14 19
131.
a. Staphylococcus aureus
e. cell wall
...
e.
a. DNA
e. Indomethacine
c.
C-3 hemisuccinoyl
ester
b. pH pKa
c.
ester
d. cosolvent
e. lyophilized
a.
b.
c.
d.
powder
138.
a. clay
b. polysaccharide
e.
c. cellulose
136.
d. hydrated silicate
e. colloidal silicone
2% A 180 ml
isotonicity
(Freezing point
= -0.52
c, freezing point
c)
a. 0.28%
b. 0.38%
c. 0.48%
d. 0.58%
e. 0.68%
137.
hydrolysis
A
a. complexing agent
dioxide
139.
140.
polymycin B sulfate
10,000 units/ml 12
.. 2548
8,500 units/ml
a.
b.
c.
d.
e.
15 25
(greasy scale)
nasolabial folds
10
betamethasone dipropionate
c. 0.05% betamethasone
psoriasis
141.
a. Contact dermatitis
b. Psoriasis
c. Saborrheic dermatitis
d. Dandruff
142.
clobetasone propionate
e. Tinea vesicolor
acetonide
b. Tar shampoo
c. Salicylic acid
d. Topical steroid
e. Ketoconazole shampoo
143.
144.
a. Ketoconazole shampoo
topical
12
steroids
b. Dandruff
topical
Topical corticosteroid
steroids
c. Sulfur keratolytic
agent
d. coal tar
photosensitivity
e. Selenium sulfide
clobetasone propionate
hyperproliferation cell
145.
chromatography
base
a. water soluble ointment base
b. oleaginous ointment base
c. emulsion ointment base
chromatography
148.
..2545
b. 8
salicylic acid
.. 2545
a.
c.
8 .. 2545
b.
d.
..2545
phospholipase A2
e.
c.
Keratolytic agent
d.
antioxidant
e.
8 .. 2545
149.
a. 1
b. 2
c. 3
d. 4
Ketoconazole
e. 5
a. Gas chromatography
b. UV/visible spectrophotometer
c. IR spectroscopy
emulsifying agent
147.
150.
b. Dexamethasone cream
c. Betamethasone + salicylic
ointment
d. Hydroxyzine tablet 25 mg
e. Methotrexate tab 2.5 mg
2549
( 2)
1 44
. Norfloxacin
. Ciprofloxacin
penicillin
1.
. Erytromycin
. Chloramphenical
. Amoxycillin
2.
10 penicillin
( anaphylaxis )
( randomized parallel)
. ( cohort
. Erytromycin
study design)
. Levofloxacin
. Chloramphenical
. Azithromycin
. Amoxycillin
3.
. Tetracyclin
6.
. Erytromycin
. Dicloxacillin
. Cotrimazole
. Amoxycillin
4.
. .. 2510
.
griseofulvin
5.
7.
flocculation
( randomized cross)
8.
Aspirin
. folic acid
. sedimentation ratio
. vitamin B 12
. ferrous gluconate
. sedimentation ratio
9. Cloxacillin sodium
.
. ferrous sulfate folic acid
12.
. G6PD
. aplastic anemia
. hemolytic anemia
. pernicious anemia
use)
. ( ready to
.
. 1
2 12
11.
. platelet
. folic acid
. vitamin B12
. ferrous sulfate
. aspirin
. Vit. c
. amoxy
. Amitryptyline
.
15 -18
19.
.
20.
.
.
21.
. Ginkgo , Tanakan
. chitosan
22.
.
. dosage form
.
. 13
23.
145 .
61 . (BMI)
. 26
. 27
. 28
. 29
. 30
24.
Phentermine
.
.
.
25. phentermine
29.
dietary fiber
. chitosan
. collagen
. Lecitin
.
.
tablet
26.
phentermine
1.
2.
3.
4. thermogenesis
27. phentermine
37.5 mg
30.
. Tapioca starch
. Confectionness sugar
28.
. magnesium stearate
4 28
31.
.
. steroid
.
.
.
32.
.
.
.
5 57
stable angina 2
.. 2542
Acute myocardial
infraction (AMI)
Atenolol 50 mg PO OD
Ramipril 10 mg PO OD
Clopidogrel 75 mg PO OD
. antibiotic
33-38
Isotretinoin
. Vitamin A
. Drug of choice
.
. serum triglyceride
40.
systemic antibiotic
39.
Isotretinoin 0.05%
Aspirin (ASA) 51 mg PO OD
SL Isosorbide dinitrate (ISDN) 5 mg Prn
6
TC
250 mg/dl
TG
41.
245 mg/dl
.
Simvastation 20
mg flollow up
. 1
.
Niacin 1gm BID
follow up 6
.
Cholestyramine 4
gm BID
.
Gentibozil 600
45.
Sublingual
mg BID
isosorbide dinitrete
(Rhabdo)
42.
statin
. genfibrozil
propanolol
. Niacin
.
. enalapril
. cholertyramine
43.
. Atenolol
. Ramipril hypokalemia
. Cholestyramine
. Gentibrosil (blurred vision)
. Isosorbide mononitrate
44.
Atenolol
.
.
.
2
46.
isosorbide
mononitrate 20 mg.
. 2
( - block)
. 2 - (3
. heart rate
cardiac output
. heart rate
. 2
-
cardiac output
. 2 -
. heart rate
. 2 - (3 )
cardiac output
. rennin
47.
. negative feedback
. Atenolol
compensatory outflow
AMI intrinsic
sympathomimetic activity
. Ramipril
. Structure ( oxide
heart failure
nitrogen
stroke
. Clopidogrel
Platelet glycoprotein I receptor
antagonist
. alcohol
50. Angiotensin-converting enzyme
(ACE) inhibitor pH
. ASA Clopidogrel
PT/ID
demand HR BP
48.
Enalapril
6 20
. dissolution
. Active ingredient
51.
. (limit)
. Sinusitis
. (limit)
. Cystitis
Enalaprilat
piperazine diketone
49.
. Allergic rhinitis
. Common cold
. Bronchitis
onset duration
52.
. Volatility
. metabolisum
60
. route of administration
Pseudoephredrine
54.
ephedrine 0.5 1 drop bid
.
1
.
1
. 1
. 2
.
.
.
.
53.
2 -
2 -
1 2 -
55.
ephedrine
ephedrine
Pseudoephedrine
. hypertension
. hyperglycemia
. rebound congestion
. insomnia
. 1,2
. 1,3
. 2,3
2,4
. 3,4
56.
. Preservative
. Coloring agent
. Buffering agent
. Antioxidant
NSS 5 ml
58.
.
.
.
60.
.
.
.
.
30
2-3
(. 1)
60 ml
120 ml
ammonium chloride
terpin hydrate)
glyceryl guaicolate
59.
.
.
2-3
61.
Aluminium hydroxide
64.
Magnesium
(rheology)
. 1 .
..............
62.
.
. 10
. -
.
.
.
.
.
65.
20
(Sedimentation rate)
10
. Cimetidine 200 mg
. 100
.63.
.
.
. (Surfactant)
methylcellulose
HCl
0.05 M
disodium
ethylendiamine
(diNaEDTA)
dithis..
Alcohol
TS
0.05 M Zn SO4
66.
69.
. Lupeol
. Curcumin
. andrographolide
67.
68.
. Stignasterol
. hydroxyanthracens
70.
H2-blocker
. 8-12
wk.
.
duodenal ulcer
gastric ulcer
.
H. pytori
. prototype
73.
29
1-2
30
3-4
71.
. T
.
1-2
.
.
. 6
74. Ergothamine
. Alkaloids
. Flavonoids
. Phenolics
. Tannins
. Terpenoids
. C
75.
. T
erythomycin
. Migraine
. M
72.
ergotamine
. Methylergotamine
. Absorption
. Amitriptyhline
. Distribution
. Sunatriptane
. Naproxen
. Verapamil
ergotamine
Caffeine 100 mg .
. Biotransformation
76.
ergotamine
. HPLC
. Ultra-Violet spectophotometry
. Potentiometry
. 6
. fluorometry
. Polamography
77.
. 2-3 /
.
80.
. Amitriptyline
. 12 .
. Propranolol
.
55
. Fluoxetine
. Ketotifen
9 58
78.
BMI = 28 kg/m
. Ergotamine
. Propranolol
. Indomethacin
. Sumatriptan
. Verapamil
79.
. 6
81.
DM
.
.
.
. desensitization of sulfonylureas
82.
. glibenclamide
30
. aspirin
receptor
receptor
. hyperinsulinemia
glibenclamide weight
. metforin
aspirin
. alcohol
metformin
gain
.
glibenclamine
83.
Metformin
glaucoma
.
.
.
isosorbide mononitrate
Metformin
glibenclamide
. rosiglitazone
. glucoside
. Chlorpropamide
84.
glibenclamide
.
87. 10
uniformity
125 mg. S
. glucagon
. Insulin
. 2%
. Insulin
. somatostatin
85.
Glibenstermine
standard deviation)
. 3%
. 4%
. 5%
. 6%
88. aspirin
1
0
Ethinyl
. faking
. picking
. paling
. mottling
. capping
89. .
.
.
.
.
.
90. glibenclamide
5 18.00 .
2
91.
. Lynestrenol
. Levonorgestrel
. Ethinyl estradiol + Levonorgestrel
. Ethinyl estradiol + Desogestrol
. Ethinyl estradiol + Gestodene
92.
. polarized
. HPLC-
UV detection
2 30 + 2
.
. Levonorgestrel 0.75 mg 2
12 .
. Ethinyl estradiol 50 g +
Levonorgestrel 17
.
.
500
00
. 98.8
. 99.8
. 100.8
. 101.8
. 102.8
95.
Levonorgestrel
. Identification IR
spectorphotometry
. Specific rotation
. Related substance
. Loss on drying
Levonorgestrel
0.75 mg 20
HPLC
Levonorgestrel 0.15
mcg/ml
3
500
. UV analysis
000
93.
le
avar
age
d
5
stand 125
124
124
124
ard
000
000
500
500
samp 128
128
127
128
96.
dose
. wet granulation
. dry granulation
. direct compression
. rifampin
5
.
corticosteroid
. Norethindrone
progestins
effect
. C=CH 2
+ Levonorgestrel
ketone
.
barbiturate
. phenyltoin
. aspirin
98. Ethinyl estradiol
. Norethindrone androgenic
Testosterone
Norethindrone
oxidation OH
. Ethinyl estradiol
estrogen
. Levonorgestrel
progestins
1.
1.
2.
3.
4.
. Levonorgestrel
11 27
. Levonorgestrel isomer
Ethinyl estradiol
Norgestrel
99. 2
- Lynestrenol
Norethindrone
. Lynestrenol estrogen
2-3
paracetamol Ibuprofen 20
Paracet
1-2 4-6
Ibuprofen 1
3
101.
104. Ibuprofen
Primary dysmenorrhea
1 .
1.
27
2. 1. mefenamic acid
3. .
2.
hyoscine-n-butylbomide
4. orphenadine
5. 5. tolperisone
paracet Ibuprofen
105.
102.
.
1. aspirine
2.
colcicine
3.
naproxen
4.
celecoxib
5.
Ibuprofen
mefenamic acid
106. major metabolite
paracetamol
Ibuprofen
Ibuprofen
103. Ibuprofen
107.
1. Serotonin
2. Prostaglandin
3. Cycloxygenase
4. Leukotriene
5. thromboxane
1.
2.
4.
3.
5.
108.
Ibuprofen
1. 2
2.
3.
4.
3.
4.
5.
12 8
..
1
para syrup
109. Paracet
..
1. punch (deep
..
concave punch )
2. die
3.
4. hygroscopic
111.
1.
2.
4.
5.
110. Ibuprofen
3.
5.
1.
2.
..
..
DTP MMR
1 ..
112. .. /
1.
114.
2.
3.
4.
5.
113. ..
1.
2.
1.
2.
3.
..
4.
5.
1. DTP vaccine
MMR vaccine
2. DTP vaccine
..
..
.. 9
..
9
MMR vaccine
/
Neomycin/bacitracin ointment
4. Calamine lotion
5. Prednisolone cream
vaccine
120.
116.
117.
1.
2.
3.
2.
Description
4.
13 22
5.
118.
1.
2.
75 kg. 155 cm
3.
4.
5.
119. .. 4
..
Diclofenac gel
..
121.
124.
diclofinac emulsion
gel
1. glucosamine sulfate
1.
3. aruanofin
3.
5.
5.
2. hydroxychloroquine
4. Prednisolone
methotrexate
122.
2.
4.
1.
2.
3.
125.
126.
1.
opioid analgesic
NSAIDs
4.
2. opioid
5. codeine para
3. NSAIDs
123.
diclofinac emulsion gel
1. carbopol
2. preservative
analgesic
4. opioid
analgesic
5. cox-2
cox-1
127.
3.
freeze- cycle
4. emulsion gel
cream
5. emulfying agent
Carboxyl group
enzyme cox-2
2. cox-2 inhibitor
cox-2
130.
...
2510
1. Diclofenac tab 25 mg
2. Piroxicam cap 10 mg
3. cox-2 inhibitor
4. cox-2 inhibitor
sulfonamide
5. cox-2 inhibitor
Cox-2
cox-1
3. Tolperisone 50 mg
Diclofenac 25 mg
1
4. Piroxicim 20mg
5. Rofecoxib 25 mg
1/1000
14
1/100
Methadone tablet 10 mg
Rofecoxib tab 25 mg
129.
Dexanethasone injection
Prednisolone tab 5 mg
131.
132.
0.9 % NaCl
1.
Atropine sulfate
2.
steroid
4.
Atropine
NaCl
8.3 g
3.
0.5 g
100 ml
H2O
1. Hypotonic solution
2. Hypertonic solution
5. ( 3. Isotonic solution
) 4. Atropine sulfate
136.
133.
aqueos humer
1. Solution
Pilocarpine
3. Ointment
Thiazide
5. Ocular insert
1. Timolol
.
.
Mannitol
Carbachol
2. Suspension
4. Cream
134.
1.
2. 0.1% Fluorometholone ED
3.
0.1% Dexamethasone ED
4. 0.5% Atropine ED
5. 0.05% Naphazoline ED
137.
1. 170
C 2 .
2.
3. sterile
membrane
4. LAL test
5. E.coli 10 cfc/ml
138.
139.
5.0
1. 24 .
2. 5
2.5
4. 1
3. 7
5. 3
140.
1. Diclofenac ED
141.
1. Breaking
3. Timolol ED
2. Cracking
4. Phase inversion
4. Dexamethazone ED
15
triamcinolone 0. %
% by weight
Triamcinolone acetonide
3. Caping
5. Phase seperation
142.
1.
2.
3.
4. (emulsifier)
5.
0.1
1.0
liquid paraffin
1. 9.5
Propylene glycol
3. 11.04
2.0
8.0
2. 10.75
4. 12.13
5. 14.0
144.
C. Triamcinolone 0.1%
D. Betametasone cream
o/w
B>D>C>A
D>A>C>B
C>D>A>B
A>D>B>C
D>B>C>A
147.
o/w
145.
1.
glucocorticoids .....
(c)17 B ketol side chain
acetonide 16
17
2.
3.
5.
triamcinolone acetonide
1.
steroid
waal force
3.
lipophilicity
4.
hydrophiliciy
5. sodium retention
148. triamcinolone
acetonide HPLC
4.
chromatogram
5.
peak
1.
flow rate
2.
injection volume
3.
column
4.
5.
mobile phase
149.
1.
49( 1)
HTN 5
HCTZ + Metoprolol
Lab BP 125/85 BUN Scr
1. Metoprolol
- heart attack
triamcinolone lotion
2. Metoprolol 5
triamcinolone lotion
3.
heart
2.
3.
triamcinolone lotion
4.
triamcinolone lotion
5.
attack
- NTG
4. NTG
5.
NTG
1. ASSAY
150. triamcinolone
2. Disolution
4. Uniformity
cream 0.1 % 15 g
1.
3. Dissintigration
6.
2 Asthma
1.
- GINA (
)
2.
- Oral thrush
6. Prednisolone
- special control
7.
- spacer (
)
8. MDI DPI
- Turbuhaler
9. Evohaler
1.
3 Glaucoma
3.
2.
4.
5.
3. 2
- steroid
4.
Betaxolol
1.
- Decrease aqueous humor production
2. -
Atropine
3.
- Hyoscine
4.
5.
6.
7. Compliance
5.
8. .
9.
1.
2.
3.
4.
5.
4 Otitis Media
6
1. - Strep
pneumo.
2.
First
choice
- Amoxycillin
3. -
Erythromycin
4.
6.
pseudoephedrine
7. Pseudoephedine
- P2
8. -
..
9. pseudoephedrine
10. 3
% LA
5 Anxiety / Depression
1. -
1 .
2. -
Zolpidem
3.
- Amitriptyline
- Purified water
4. -
5.
5. Preservative
- Paraben
Sertaline
6. fluoxetine
5.
7. -
6 Parkisonism
?
levodopa/Carbidopa
4. Progestogen
Ibuprofen 400 mg
MTV
1.
6.
8 Primary dysmennrhea +
+
5
Levodopa/Carbidopa
1.
2.
2. On Off
3.
4. Psychosis
MTV
5.
SAR
7 Oral Contraceptives
1. Phyto
Estrogen
2. 3
3. EE
3.
4. Displcement
Value = 2 1
20
5.
-
6.
9 Cysitis
1.
2.
3. Norfloxacin
4. 1 gr / 2 flz
5.
-
10 Gout
20
Lab
gout
1.
1.
2.
2. Colchicine
3.
1
6. Colchicine
7. Colchicine
8. K Shelf-
life
- 0.104/K
11 Diabetes Miletus
3.
4.
Type II
5.
2 Insulin
2. gout attack -
3.
Allopurinol
4.
5.
1. -
hypoglycemia
2. - Glucose
3. Shift electron
Chlopropamide
Tolbutamide
4. Insulin -
5. Insulin
14. Thiazolididione
Glucagon
6. NPH
7. Insulin
8. Sulfonylurea
- Hepatotoxicity
15.
12 Peptic Ulcer
3-5
1. Antacid
Sulfonylurea
2.
9.
- Glipizide
Glipizide!?
10. Glipizide
1. Sulfonylurea----
2. Sulfone
11.
- 7
-
3.
-
4. Antacid
5. GU, DU
6.
Scr
7. H2 Block
8.
12.
13. Thiazolidinedione
Type I
Triple therapy
- 3
9.
- curcumin
10.
13 Hypersensitivity
1. Type
2.
- Hydroxyzine 10
mg 1 x 3
3.
-
4.
5.
6.
7.
14 Vitamin A Deficiency
3.
-
4.
- Cholestyramine
5. Cod liver oil
6. Preservative
7.
8. % RDA
RDA -
1.
5-6
1.
Immunoglobulin
Immunoglobulin
2.
-
tetanus
2.
3.
Imunoglobulin
- Active
HMI
49( 2)
1 Heart Failure
4. - 5
HF HCTZ
1.
2. HCTZ - Gout
5. 2
-
HCTZ
4.
6. 5 6
5. HCTZ
7.
8.
Dry freeze
9. Pka
Pka
pH .
6.
HCTZ
7. 25 mg
1 1
- 30
2 Hyperlipidemia
Lab
LDL +
Lab 7-8
1.
- atorvastatin
Lab
2.
Prodrug
3. Statin
- hepatotoxic
Lab
aminotransferrase
4. -
Gemfibrozil
4. -
Diclofenac
5.
6.
7. -
8. -
5 HRT
5. Guideline
1.
6. -
2.
7.
3.
- CUA
vasomotor symptom
EE
3 DM
6 Osteoartritis
40 40
Renal
Diclofenac
1.
2.
3. Diclofenac -
Glucosamine
1.
2. OA
- --- , ,
3. / OA
4. Glucosamine
5. Glucosamine
6. Calcium carbonate xx mg /
tab calcium
yyy mg
7. Calcium
8. specific cox 2
7 Opportunistic Infections
1. -
2. -
pessaries
3. - PEG
5. 5
6. Ketoconazole
- CMA
7. pKa pH %
+ Lab + +BSA
1. BSA
2. BSA
10 Pregnancy
1. Isotretinoin cat - X
2. - teratogenic
3. Insulin
4. Prophylaxis OIs
4.
6. CI 1
5.
5.
significant
11 Allergy
1.
2. - ketoconazole
3. - 200 mg OD
4. Ketoconazole
1. Mediator
2.
3. -
CPM
4.
- 4
Low
5.
3
6.
7. Cetyl
acohol
12 Migraine
1.
- Rofecoxib
2.
15 Diarrhea
2
1. - Loperamide
2.
3. 5 - anova
Article 1.
3. Ergotamine
1. Thiethanolamine
4. Ergotamine
3. Rx
5.
13 Bacteria Pharyngitis
Amoxy
1. -
2.
3. Rhinitis medicament
4. 4 -
14 Bacteria conjunctivitis
1.
2.
3. meq/L
2. Zeta Potential
x ml
meq
5.
6.
7. Theobroma oil
8.
9. 8 Assay .
3.
vac.
1.
4. DTP
( 40 )
vac.
2. Science
5. pt. rabies
Care
vac.
3.
choice
4. Law
5. Econ 2 Epidermio 1
2. + tetanus
Research 1
3. + rabies
6. medchem assay
1. + betadine
6.
vac.
Case 3 Migraine
1. (
50 ( 1)
Case 1
PU
vaccine
1. vac.
.......
2.
vac.
pt.
1. cisapride
Case 2
Case
(BCG)
metoclopramide + Ibuprofen
2. metoclopramide
3.
Case 4
prerenal, intrinsic
Cystitis
Pt.
BUN/Scr >20:1 )
2. lab
hypokalemia ,
1.
azotemia
3.
2. pt.
.)
Pt.
1
3.
4.
pt.
urine
2. isotonic
5.
capsule
Case 5 Cancer
Case 9 Asthma
, . pt.
s/e
Case 11 DM 2
Case 6 renal
Pt. lab (
urine)
1.
Case 13 Hyperlipidemia (
)
Case 14 NSAIDs
Case 15 + HRT
50 ( 2)
3.
GI
4.
Case 1
1.
choice
5. .
2.
KMnO4
3.
pt.
( case)
6.
4. DV
5. Pt.
15 3
1.
Pco
2.
Case 2 Hypothyroid
Lab
FT4 TSH
1.
2. /
(Myxo)
3.
(Hashimoto.)
4. drug of choice
(levothyroxine)
5.
receptor
(I
D L DL
form)
6.
(
T3 3
5 .......)
7.
choice
therapy
TSH 46 )
Case 3 Glaucoma
Pt.
1. pt.
2.
pt.
3. /
( )
( 3-4 )
fluoxetine /
amitrip.
pt.
1.
2. (
)
3. SSRIs ..............
4.
(
fluoxetine
MCQ & OSPE )
Case 5 Toxicology
4. pt.
Pt.
5. sterile
para.
6.
...........
7. , pKa
1.
2. Antidote
3. func. Group
4.
(
pH /
pKa )
Case 4 Depression
antidote
( effervescent
)
5. Dead mixture
Case 6 DM + hyperlipidemia
1. pt.
2
........
2.
2. NPH
1.
3. pt.
2.
intermediate
3. Emulsifier
Case 7 HIV + TB
Pt.
1. Opportunistic infection
2.
CD4/ CD8
????
3.
metabolic
( PIs)
abacarvir NRTIs
Case 8
1. Calamine
lotion
4. flocculating
5.
Case 9 /
, )
Case 11 HRT
Case 12 HTN
Case 13 RA + OA
Case 14 Sinusitis
Case 15 URI
Ospe
2551
3-4
(
49 3),
( 50 2
7)
MCQ