Christian Bohr discovered that hemoglobin binds to oxygen with less affinity in more acidic environments due to increased carbon dioxide levels. According to the Bohr effect, higher carbon dioxide in the blood decreases pH, which causes hemoglobin to release oxygen more easily in tissues. The Bohr effect explains how hemoglobin unloads oxygen in tissues based on carbon dioxide levels, as described in physiological textbooks.
Christian Bohr discovered that hemoglobin binds to oxygen with less affinity in more acidic environments due to increased carbon dioxide levels. According to the Bohr effect, higher carbon dioxide in the blood decreases pH, which causes hemoglobin to release oxygen more easily in tissues. The Bohr effect explains how hemoglobin unloads oxygen in tissues based on carbon dioxide levels, as described in physiological textbooks.
Christian Bohr discovered that hemoglobin binds to oxygen with less affinity in more acidic environments due to increased carbon dioxide levels. According to the Bohr effect, higher carbon dioxide in the blood decreases pH, which causes hemoglobin to release oxygen more easily in tissues. The Bohr effect explains how hemoglobin unloads oxygen in tissues based on carbon dioxide levels, as described in physiological textbooks.
Christian Bohr stated that at lower pH (more acidic environment, e.g.,
in tissues), hemoglobin would bind to oxygen with less affinity. Since carbon dioxide is in direct equilibrium with the concentration of protons in the blood, increasing blood carbon dioxide content, according to the Bohr effect, causes a decrease in pH, which leads to a decrease in affinity for oxygen by hemoglobin (and easier oxygen release in capillaries or tissues). The description of the Bohr effect, which is a physiological law, can be found in nearly all physiological textbooks. Modern studies related to the Bohr effect are devoted to more advanced topics (see the titles of studies for modern research below). It is the central proposition of the Bohr effect that oxygen affinity to hemoglobin depends on absolute CO2 concentrations and reduced CO2 values decrease oxygen delivery to body cells. http://www.normalbreathing.com/CO2-bohr-effect.php