GYPE

Glycophorin-E is a protein that in humans is encoded by

the GYPE gene.[2]

doi:10.1111/j.1432-1033.1990.tb19166.x. PMID
2390989.

The protein encoded by this gene is a sialoglycoprotein

and a type I membrane protein. It is a member of a
gene family with GPA and GPB genes. This encoded
protein might carry the M blood group antigen. GYPA,
GYPB, and GYPE are organized in tandem on chromosome 4. This gene might have derived from an ancestral
gene common to the GPB gene by gene duplication. Two
alternatively spliced transcript variants encoding the same
protein have been described for this gene.[2]

Kudo S, Fukuda M (1994). Contribution of gene

conversion to the retention of the sequence for
M blood group type determinant in glycophorin E
gene. J. Biol. Chem. 269 (37): 2296974. PMID
7521873.

Onda M, Fukuda M (1995). Detailed physical

mapping of the genes encoding glycophorins A,
B and E, as revealed by P1 plasmids containing
human genomic DNA. Gene. 159 (2): 225
230. doi:10.1016/0378-1119(95)00075-H. PMID
7622054.

References

Kudo S, Onda M, Fukuda M (1995). Characterization of glycophorin A transcripts: control by the

common erythroid-specic promoter and alternative usage of dierent polyadenylation signals. J.
Biochem. 116 (1): 18392. PMID 7798177.

[1] Human PubMed Reference:".

[2] Entrez Gene: GYPE glycophorin E.

Further reading

Huang CH, Chen Y, Blumenfeld OO (2000). A

novel St(a) glycophorin produced via gene conversion of pseudoexon III from glycophorin E to glycophorin A gene. Hum. Mutat. 15 (6): 533540.
doi:10.1002/1098-1004(200006)15:6<533::AIDHUMU5>3.0.CO;2-R. PMID 10862083.

Cartron JP, Rahuel C (1992). Human erythrocyte glycophorins: protein and gene structure analyses. Transfusion medicine reviews. 6 (2): 63
92. doi:10.1016/S0887-7963(92)70158-8. PMID
1591491.

Strausberg RL, Feingold EA, Grouse LH, et al.

(2003). Generation and initial analysis of more
than 15,000 full-length human and mouse cDNA
sequences. Proc. Natl. Acad. Sci. U.S.A. 99
(26): 1689916903. doi:10.1073/pnas.242603899.
PMC 139241 . PMID 12477932.

Huang CH, Skov F, Daniels G, et al. (1992).

Molecular analysis of human glycophorin MiIX
gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via
sequence repeats. Blood. 80 (9): 237987. PMID
1421409.

Wang HY, Tang H, Shen CK, Wu CI (2004).

Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria
parasites. Mol. Biol. Evol. 20 (11): 17951804.
doi:10.1093/molbev/msg185. PMID 12949139.

Vignal A, London J, Rahuel C, Cartron JP (1991).

Promoter sequence and chromosomal organization of the genes encoding glycophorins A, B and
E. Gene. 95 (2): 289293. doi:10.1016/03781119(90)90374-Z. PMID 2249783.

Gerhard DS, Wagner L, Feingold EA, et al. (2004).

The status, quality, and expansion of the NIH fulllength cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 21212127.
doi:10.1101/gr.2596504. PMC 528928 . PMID
15489334.

Kudo S, Fukuda M (1990). Identication of a

novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA
clones utilizing polymerase chain reaction. J. Biol.
Chem. 265 (2): 110210. PMID 2295603.
Vignal A, Rahuel C, London J, et al. (1990). A
novel gene member of the human glycophorin A
and B gene family. Molecular cloning and expression. Eur. J. Biochem. 191 (3): 619625.
1

3 TEXT AND IMAGE SOURCES, CONTRIBUTORS, AND LICENSES

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3.1

Text

GYPE Source: https://en.wikipedia.org/wiki/GYPE?oldid=722945887 Contributors: Alaibot, ProteinBoxBot, Addbot, DOI bot, Citation
bot, Citation bot 1, BogBot, Trappist the monk and Dcirovic

3.2

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File:DNA_stub.png Source: https://upload.wikimedia.org/wikipedia/commons/6/61/DNA_stub.png License: CC-BY-SA-3.0 Contributors: Transferred from en.wikipedia to Commons by Rockfang. Original artist: The original uploader was Alai at English Wikipedia
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Free-to-read_lock_75.svg Original artist: User:Trappist the monk
File:PBB_GE_GYPE_207854_at_tn.png Source: https://upload.wikimedia.org/wikipedia/commons/4/4b/PBB_GE_GYPE_207854_
at_tn.png License: CC BY-SA 3.0 Contributors: Transferred from en.wikipedia. Diagram created by AndrewGNF based on data from
Su AI, Wiltshire T, Batalov S, et al (2004). A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl. Acad. Sci.
U.S.A. 101 (16): 60627. doi:10.1073/pnas.0400782101. PMID 15075390. Creation supported by the Genomics Institute of the Novartis
Research Foundation. Original artist: AndrewGNF at en.wikipedia

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