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Pharmacology - MCQs
Pharmacology - MCQs
Pharmacology - MCQs
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1. Cimetidine:
a) lowers plasma creatinine
b) prolongs the prothrombin time
c) hastens gastric emptying
d) may potentiate the action of warfarin
e) may impair cardiac conduction
2. Acute intermittent porphyria:
a) is exacerbated by digoxin
b) is precipitated by sulphonamides
c) is precipitated by ethyl alcohol
d) is treated by parenteral lidocaine
e) contraindicates the use of thiopentone
3. The following are features of digoxin toxicity:
a) headache
b) nausea
c) abdominal pain
d) convulsions
e) coupled beats
4. Lidocaine can cause:
a) sedation
b) convulsions
c) slowed A-V conduction
d) prolongation of the cardiac action potential
e) shortening of the refractory phase
5. Features of severe aspirin overdose include:
a) tinnitus
b) metabolic acidosis
c) a reduction in the platelet count
d) haemolysis
e) hyperventilation
6. Atropine antagonises the action of:
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14. Phenobarbitone:
a) is used in the treatment of grand mal epilepsy
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1. Dopamine:
a) may produce ventricular arrhythmias
b) increases mesenteric blood flow at high doses
c) crosses the blood-brain barrier
d) is synthesised from L-dopa
e) is inactivated in alkaline solution
2. The following increase the amount of calcium in cardiac muscle:
a) halothane
b) adrenaline
c) diltiazem
d) nifedipine
e) trimetaphan
3. The following can be used safely in a patient on a monoamine oxidase
inhibitor:
a) morphine
b) pethidine
c) noradrenaline
d) amphetamine
e) adrenaline
4. Hyoscine hydrobromide causes:
a) antiemesis
b) somnolence
c) pupillary dilatation
d) tachycardia followed by bradycardia
e) extrapyramidal symptoms
5. Clonidine:
a) is an alpha-2 receptor agonist
b) is a dopamine antagonist
c) causes tachycardia
d) inhibits salivation
e) reduces the minimum alveolar concentration of halothane
ANSWERS
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6. Hydralazine:
a) is metabolised by acetylation
b) is destroyed by plasma cholinesterase
c) can cause a lupus-like syndrome
d) stimulates the baroreceptor reflex
e) is contraindicated in pregnancy
7. The following are prodrugs:
a) suxamethonium
b) diamorphine
c) captopril
d) paracetamol
e) enalapril
8. The following drugs penetrate the blood-brain
barrier:
a) physostigmine
b) dopamine
c) propranolol
d) glycopyrrolate
e) noradrenaline
9. Naloxone:
a) is an agonist at kappa receptors
b) is an antagonist at mu receptors
c) reverses ventilatory depression due to morphine
d) may precipitate opiate withdrawal symptoms
e) may cause pulmonary oedema
10. The following are precursors of adrenaline:
a) tyrosine
b) phenylalanine
c) dopamine
d) isoprenaline
e) noradrenaline
ANSWERS
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ANSWERS
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ANSWERS
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ANSWERS
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ANSWERS
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1. Nifedipine:
a) causes tachycardia
b) causes tremor
c) causes hypoglycaemia
d) can be given sublingually
e) dilates skeletal muscle arterioles
2. Tetracycline:
a) may be hepatotoxic in large doses
b) is extensively metabolised
c) is contraindicated in pregnancy
d) potentiates non-depolarising muscle relaxants
e) absorption is decreased by magnesium trisilicate
3. Neostigmine:
a) is eliminated entirely by the liver
b) causes foetal bradycardia when given to a pregnant woman
c) causes miosis
d) is a quaternary ammonium compound
4. The following drugs readily cross the placenta:
a) atracurium
b) lidocaine
c) bupivacaine
d) neostigmine
e) propranolol
5. In acute intermittent porphyria, the following, drugs may be safely
used:
a) etomidate
b) ketamine
c) midazolam
d) pethidine
e) cotrimoxazole
ANSWERS
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11. Atropine:
a) increases gut motility
b) is a mixture of d- and l-isomers
c) is equipotent with hyoscine
d) can cause bradycardia
e) crosses the blood-brain barrier
12. Beclomethasone:
a) can be given by aerosol inhaler
b) can cause candidiasis
c) is a fludrocortisone
d) increases the circulating cortisol concentration
e) is a bronchodilator
13. Dopamine receptor antagonists:
a) increase heart rate
b) are antiemetics
c) cause hypertension
d) cause extrapyramidal side-effects
e) increase lower oesophageal sphincter tone
14. The volume of stomach contents is reduced by:
a) sodium citrate
b) metoclopramide
c) cimetidine
d) atropine
e) pyridostigmine
15. The following drugs relax the pregnant uterus:
a) salbutamol
b) propranolol
c) noradrenaline
d) acetylcholine
e) dopamine
ANSWERS
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