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  • Non Narcotic Analgesics

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    Salicylates like aspirin are common non-narcotic analgesics that are absorbed through the gastrointestinal tract. While effective at reducing pain, they can cause unwanted gastrointestinal, bleeding, uric acid, and blood thinning side effects. Acetaminophen is another non-narcotic analgesic, but can potentially lead to blood or liver problems in high doses. Phenacetin was also used but removed from the market due to blood toxicity issues. In summary, this document outlines several common non-narcotic pain relievers like aspirin and acetaminophen, along with their mechanisms of action and potential adverse effects.

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    Salicylates like aspirin are common non-narcotic analgesics that are absorbed through the gastrointestinal tract. While effective at reducing pain, they can cause unwanted gastrointestinal, bleeding, uric acid, and blood thinning side effects. Acetaminophen is another non-narcotic analgesic, but can potentially lead to blood or liver problems in high doses. Phenacetin was also used but removed from the market due to blood toxicity issues. In summary, this document outlines several common non-narcotic pain relievers like aspirin and acetaminophen, along with their mechanisms of action and potential adverse effects.

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    23 views1 page

    Non Narcotic Analgesics

    Uploaded by

    mzhlean
    Salicylates like aspirin are common non-narcotic analgesics that are absorbed through the gastrointestinal tract. While effective at reducing pain, they can cause unwanted gastrointestinal, bleeding, uric acid, and blood thinning side effects. Acetaminophen is another non-narcotic analgesic, but can potentially lead to blood or liver problems in high doses. Phenacetin was also used but removed from the market due to blood toxicity issues. In summary, this document outlines several common non-narcotic pain relievers like aspirin and acetaminophen, along with their mechanisms of action and potential adverse effects.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    NON-NARCOTICS

    1. Salicylates
    a. Salicylic acid parent compound, toxic internally
    b. Sodium Salicylate internal use as an analgesic, may be used in patients
    allergic to aspirin
    c. Methyl Salicylate external use, flavoring in cooking
    d. Acetylsalicylic acid most commonly used, Triple Asl
    e. Salicylamide less GI irritation
    f. Diflunisal
    2. Aspirin
    - Absorbed from the GIT
    Unwanted effects:
    a. Gastrointestinal
    b. Haemostatic effect
    c. Uricosuric effect
    d. Antithrombotic effect
    3. Pura-Aminophenols
    3.1.
    Acetaminophen
    Adverse effect: Hemolytic Anemia, Hepatic Necrosis
    3.2.
    Phenacetin
    Adverse effect: Methemoglobinemia

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