Professional Documents
Culture Documents
Ent and Anesthesia PDF
Ent and Anesthesia PDF
Ent and Anesthesia PDF
1/79
Test Information
Test Name
Total Questions
200
Test Type
Examination
Difficulty Level
Difficult
Total Marks
600
Duration
120minutes
Which of the following inhalation anaesthetics should be avoided in middle ear surgery?
a. Halothane
b. Nitrous oxide
c. Ether
d. Isoflurane
Solution. Ans-1: (b) Nitrous oxide
Ref.:Read the text below
Sol :
- Nitrous oxide enters closed air spaces like middle ear from blood stream and leads to expansion of air cavity.
- This may cause displacement of grafts or prosthesis.
Correct Answer. b
(2).
2/79
(3).
(4).
In head and neck cancer, Ohngren's line is a line that connects the medial canthus of the eye to the angle of the mandible.
The line defines a plane orthogonal to a sagittal plane that divides the maxillary sinus into (1) an anterior-inferior part, and (2)
a superior-posterior part.
Tumours that arise in the anterior-inferior part, i.e. below Ohngren's line, generally have a better prognosis than those in the other group
Correct Answer. a
(5).
3/79
(6).
The tympanic nerve (Jacobson nerve, a branch of cranial nerve IX) directly innervates the ear but also has pharyngeal, lingual, and
tonsillar branches to supply the posterior one-third portion of the tongue, tonsillar fossa/pillars, pharynx, eustachian tube
Correct Answer. c
(7).
(8).
Central neuroaxial blockade if the patient is on LMWH, then ow much hours before surgery it must be stopped?
a. 2-4 hrs
b. 4-8 hrs
c. 8-12 hrs
d. 12-24 hrs
Solution. Ans-8: (c) 8-12
Ref.:Read the text below
Sol :
Different books and literature havementioned different guideline to stop LMWH.
But the standard criterion by ARSA mentions : LMWH should be held for 10-12 hours prior to neuraxial blockade for normal dosing.
Correct Answer. c
4/79
(9).
Approach used for Brachial plexus block include the following except
a. Suprascapular
b. Interscalene
c. 3 in 1 block
d. Axillary
Solution. Ans-9: (c) 3 in 1 block
Ref.:Read the text below
Sol :
Brachial plexus block approaches :
Continuous interscalene approaches
Interscalene block classic approach.
Intersternocleidomastoid approach
Parascalene approach
Paravertebral approach (Posterior Approach)
Continuous Infraclavicular approaches :
The coracoids Approach of whiffler
The modified approach of the Raj Technique
Correct Answer. c
(10).
(11).
5/79
(12).
Superior border
Inferior border
Nasopharynx/ epipharynx
Oropharynx
Hypopharynx
Correct Answer. a
(13).
(14).
Inflammation with subsequent thrombus formation of the sigmoid and/or transverse sinus
Griesingers sign(pain over mastoid from occlusion of the mastoid emmisary vein)
Tobey-Ayer or Queckenstedts test(normally external compression of jugular vein results in a rapidincrease in CSF pressure of
50100 mm Hg, compression on theside of lateral sinus thrombosis results in a slow rise or no rise inCSF pressure secondary to
obstruction
Parenteral antibiotics and possible surgical exploration via a mastoidectomy, may require ligation of internal jugular vein
recalcitrant disease.
Correct Answer. a
6/79
(15).
Ayers T piece is :
a. Mapelson A circuit
b. Mapelson B circuit
c. Mapelson D circuit
d. Mapelson E circuit
Solution. Ans-15: (d) Mapelson E circuit
Ref.:Read the text below
Sol :
The Mapleson E is a modificationof Ayre s T-piece, which was developed in 1937 by Phillip Ayre for use in paediatric patients
undergoing cleft palate repair or intracranial surgery.
Correct Answer. d
(16).
Which of the following is a pleasant anesthetic agent preferred for inhalation mask anaesthesia in children?
a. Sevolfurane
b. Desflurane
c. Isoflurane
d. Enflurane
Solution. Ans-16: (a) Sevolfurane
Ref.:Read the text below
Sol :
Sevoflurane, with low bloodgas solubility allows rapid induction and early emergence.
Due to its pleasant odor, it is non irritant to the airway which makes it an attractive alternative for inhalational induction in children.
An area where sevoflurane might be expected to find increasing use is that of laryngeal mask airway (LMA) insertion which is
becoming more frequent in paediatric ambulatory surgery as this avoids some of the hazards of endotracheal intubation.
Correct Answer. a
(17).
7/79
(18).
(19).
Portion of middle ear around the tympanic orifice of the eustachian tube is:
a. Mesotympanum
b. Epitympanum
c. Hypotympanum
d. Protympanum
Solution. Ans-19: (d) Protympanum
Ref:Read the text below
Sol :
Middle ear is sometimes divided into
Mesotympanum (opp. the pas tensa)
Epitympanum(attic) above the pas tensa
Hypotympanumbelow the pas tensa
Protympanum portion of middle ear around the tympanic orifice of the eustachian tube
Narrowest part of middle ear: mesotympanum
Widest part of middle ear: Epitympanum
Correct Answer. d
8/79
(20).
Rhinosporidiosis
Organism : Rhinosporidium seeberi
Distribution:India (Southern parts), Sri lanka
Sites of Affection:
1. Most commonly: Nose and Nasopharynx
Mulberry shaped polypoidal massstudded with white dots or sporangia on its under surface.
Site: Vestibule (septal area)
Treatment:
Complete excision of the mass with a cutting diathermy and cauterization of its base.
Medical management: Local injection of corticosteroids and courses of dapsone and amphotericin.
Correct Answer. a
(21).
(22).
Pathophysiology: most commonly arise from internal posterior cricoid cartilage (hyaline cartilage), may also arise from thyroid,
arytenoid, epiglottic cartilage (fibroelastic)
SSx: insidious hoarseness from vocal fold restriction, dyspnea for subglottic lesions, dysphagia for posterior cricoid lesions, globus
sensation
Rx: complete excision via an endoscopic or external approach (depending on the size of lesion)
Correct Answer. a
9/79
(23).
Cleft pinna
Coloboma lobuli
Macrotia
Microtia
Melotia
Low-set-ears
Polyotia
Preauricular tags
Scroll ear
Correct Answer. b
(24).
Indications
Contraindications
Correct Answer. c
10/79
(25).
(26).
11/79
(27).
Laser Assisted Myringotomy, sometimes referred to as OtoLAM, for OtoScan Laser Assisted Myringotomy (OtoScan is the tradename
of one of the otoscope-mounted systems used), is a treatment that utilizes a laser to create the hole in the eardrum rather than using a
surgical incision.
The laser technique is less invasive than surgical incision and can be performed in an office setting or outpatient clinic using only
topical anesthesia. With the aid of a specialized CO2 laser system, the procedure creates a precisely sized hole in the tympanic
membrane that remains open for several weeks.
During this time, the middle ear stays ventilated, providing fast relief from otitis media related pain and allowing the underlying
infection time to resolve.
If more time is needed for resolution, tubes can easily be inserted into the bloodless hole, although at the expense of increasing
invasiveness over just the laser technique alone. Clinical studies found that 60% of the cases resolved after a single OtoLAM treatment
and clearing the underlying infection helps prevent recurring episodes of otitis media.
Correct Answer. b
(28).
Local anaesthetic solutionsare deposited in the epidural space between the dura mater and the periosteum lining the vertebral
canal. The epidural space contains adipose tissue, lymphatics and blood vessels. The injected local anaesthetic solution produces
analgesia by blocking conduction at the intradural spinal nerve roots.
The quality and extent of the blockade produced by each agent is determined by the volume as well as the total dose of the drug. The
spread of local anaesthetic solutions may be more extensive ipregnant women as the volume of the potential space is reduced by venous
engorgement in the epidural space. Enhanced effects may also be seen in the elderly and in patients with arteriosclerosis due to
impairment of vascular absorption from the epidural space.
Bupivacaine (0.5%) or lignocaine (1.5-2.0%) are usually used to produce extradural anaesthesia. Repeated administration of
lignocaine or mepivacaine into the epidural space may result in a diminished response with each subsequent dose (tachyphylaxis). This
may be due to local changes in pH due to the relative acidity of these solutions. The reduction in pH may reduce the amount of free base
available for diffusion across the neuronal membrane
Correct Answer. a
12/79
(29).
Myringotomy is a surgical procedure in which a tiny incision is created in the eardrum, so as to relieve pressure caused by the
excessive build-up of fluid, or to drain pus.
(30).
Embryologic development
The Eustachian tube is derived from the first pharyngeal pouch, which during embryogenesis forms a recess called the tympanic
membrane. The distal part of the tubotympanic sulcus gives rise to the tympanic cavity, while the proximal tubular structure becomes the
Eustachian tube.
Muscles
There are four muscles associated with the function of the Eustachian tube:
(31).
Secretory (serous) otitis media can develop from acute otitis media that has not completely cleared or from a blocked eustachian
tube (which connects the middle ear and the back of the nose).
13/79
(32).
The Weber test is a quick screening test for hearing. It can detect unilateral (one-sided) conductive hearing loss and unilateral
sensorineural hearing loss.
Detection of conductive hearing loss
A patient with a unilateral conductive hearing loss would hear the tuning fork loudest in the affected ear. This is because the
conduction problem masks the ambient noise of the room, whilst the well-functioning inner ear picks the sound up via the bones of the
skull causing it to be perceived as a louder sound than in the unaffected ear.
Detection of sensorineural hearing loss
A patient with a unilateral sensorineural hearing loss would hear the sound louder in the unaffected ear, because the affected ear is
less effective at picking up sound even if it is transmitted directly by conduction into the inner ear.
Correct Answer. a
(33).
Pre-medication with the following causes tachycardia, flushing of face and hyperthermia in children:
a. Atropine
b. Chlorpromazine
c. Glycopyrrolate
d. Clonazepam
Solution. Ans 33: (a) Atropine
Ref Read the text below
Sol:
Atropine, a parasympatholytic, causes tachycardia and at high doses causes sweating inhibition, hyperthermia (=Atropine fever) and
flushing of face.
Children are especially more susceptible for the vascular effects of atropine.
Correct Answer. a
(34).
Additional benefits of morphine are sedation and decreased apprehension and anxiety.
Correct Answer. d
14/79
(35).
Out of all the anticholinergics mentioned, only Hyoscine has additional anti-emetic and amnesic effects.
Correct Answer. b
(36).
They are thinly myelinated, so conduct signals more rapidly than unmyelinated C fibers, but more slowly than other, more thickly
myelinated "A" class fibers.
Because of their higher conduction velocity, A fibers are responsible for the sensation of a sharp first pain. They respond to a
weaker intensity of stimulus. C fibers, however, respond to a stronger intensity of stimulus and are responsible for the slow, dull, longerlasting, second pain.
C fibers are considered polymodal because they can respond to thermal, mechanical, and chemical stimuli.C fibers respond to all kinds of
physiological changes in the body. For example, they can respond to hypoxia, hypoglycemia, hypo-osmolarity, the presence of muscle
metabolic products, and even light or sensitive touch.C fiber receptors include:
C fiber nociceptors
o Responsible for the second, burning pain
C fiber warming specific receptors
o Responsible for warmth
Ultra-slow histamine-selective C fibers
o Responsible for itch
Tactile C fibers
o Sensual touch
C mechano- and metabo- receptors in muscles or joints
o Responsible for muscle exercise, burn and cramp
Correct Answer. a
15/79
(37).
Lidocaine is a common local anesthetic and antiarrhythmic drug. Lidocaine is used topically to relieve itching, burning and pain from
skin inflammations, injected as a dental anesthetic or as a local anesthetic for minor surgery.
Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na+) channels in the neuronal cell
membrane, which are responsible for signal propaga
tion.
With sufficient blockade, the membrane of the postsynaptic neuron will not depolarize and so fail to transmit an action potential,
leading to its anaesthetic effects.
Correct Answer. b
(38).
Mayer and overton founda direct relationship between lipid solubility of the general anesthetic and its anesthetic potency.
The more an agent is lipid soluble, the more it crosses all (lipophilic) membranes, cross BBB and produce CNS effects
Correct Answer. c
(39).
Adrenaline causes vasoconstriction, so decreases rate of removal of lignocaine from the deposited site.
Therefore, addition of adrenaline, increases duration of L.A. action and decreases adverse effects of lignocaine.
Adrenaline should never be used in organs of end-arteries e.g. penis, finger, nose, ear-pinna.
Correct Answer. b
16/79
(40).
A patient who has an untreatable hepatic carcinoma must undergo foot surgery. All of the following local anesthetic agents may be
deleterious to this patient based on his history, except
a. Lidocaine
b. Mepivacaine
c. Procaine
d. Etidocaine
Solution. Ans 40: (c) Procaine
Ref Read the text below
Sol:
Lidocaine, mepivacaine, and etidocaine are amides, so metabolized in the liver by microsomal mixed-function oxidases.
Thus, procaine would be the anesthetic agent of choice, as in this patient hepatic function impairment is there. (Procaine does not
require liver enzymes to be metabolized)
Correct Answer. c
(41).
A patient with pseudocholinesterase deficiency requires minor surgery. A local anesthetic will be used. The choice of an anesthetic agent
will depend on all of the following factors, except
a. Procaine should not be used in the patient because a psuedocholinisterase deficiency would lengthen its duration of action
b. Tetracaine should not be used because it is most commonly used for spinal anesthesia.
c. Dibucaine would be contraindicated since it is a surface anesthetic.
d. Although cocaine has abuse potential, because it is metabolized in the liver, it would be of therapeutic value in this case.
Solution. Ans 41: (d) Although cocaine has abuse potential, because it is metabolized in the liver, it would be of therapeutic value in this
case.
Ref Read the text below
Sol:
Cocaine is an ester linked local anesthetic like procaine. It is also metabolized via ester hydrolysis in the blood by pseudocholinesterase and is not metabolized in the liver.
Therefore, cocaine should not be used in this patient with cholinesterase deficiency.
Correct Answer. d
(42).
A noise of 90dB(A) SPL, 8hrs a day for 5 days per week is the maximum safe limit
The audiogram of NIHL shows a typical notch at 4khz, both for AC & BC. It is usually symmetrical on both sides. NIHL causes
damage to hair cells, starting in the basal turn of cochlea. Outer hair cells are affected before the inner hair cells
17/79
(43).
(44).
The parasympathetic aspect of the facial nerve controls secretion of the sublingual and submandibular salivary glands, the lacrimal
gland, and the glands associated with the nasal cavity.
The preganglionic fibers originate within the CNS in the superior salivatory nucleus and leave as the intermediate nerve (which
some consider a separate cranial nerve altogether) to connect with the facial nerve just distal (further out) to it surfacing the CNS. Just
after the facial nerve geniculate ganglion (general sensory ganglion) in the temporal bone, the facial nerve gives off two separate
parasympathetic nerves. The first is the greater petrosal nerve and the second is the chorda tympani.
The greater petrosal nerve travels through the middle ear and eventually combines with the deep petrosal nerve (sympathetic fibers)
to form the nerve of the pterygoid canal. The PSN fibers of the nerve of the pterygoid canal synapse at the pterygopalatine ganglion,
which is closely associated with the maxillary division of the trigeminal nerve (CN V2).
The postganglionic PSN fibers leave the pterygopalatine ganglion in several directions.One division leaves on the zygomatic division
of CN V2 and travels on a communicating branch to unite with the lacrimal nerve (branch of the ophthalmic nerve of CN V1) before
synapsing at the lacrimal gland. These PSN to the lacrimal gland control tear production.
Correct Answer. a
18/79
(45).
Its water solubility is poor, so etomidate is formulated in a propylene glycol solution. Induction is rapid, and the drug is short-acting.
It is only used for patients with coronary artery disease or cardiovascular dysfunction, such as shock.
Among its benefits are little to no effect on the heart and circulation. Its adverse effects include a decrease in plasma cortisol and
aldosterone levels, which can persist for up to 8 hours. This is apparently due to inhibition of 11--hydroxylase.
Etomidate should not be infused for an extended time, because prolonged suppression of these hormones can be hazardous.
Venous pain can occur, and skeletal muscle movements are not uncommon.
(46).
Patient with liver disease and Mitral Stenosis posted for surgery. All should not be given for induction of anesthesia except
a. Halothane
b. Enflurane
c. Xenon
d. Sevoflurane
Solution. Ans-46: (c) Xenon
Ref: Morgan Clinical Anesthesiology4th ed.
Sol:
Clinical Pharmacology of Inhalational Anesthetics.
Nitrous Oxide
Halothane
Isoflurane
Desflurane
Sevoflurane
Decrease
Decrease
Decrease
Decrease
Hepatic
Blood flow
Environmentally friendly
Nonexplosive
Disadvantages
High cost
Correct Answer. c
19/79
(47).
2 and 5
Nitrous oxide
3 and 5
Entonox
Carbon dioxide
1 and 6
Cyclopropane
3 and 6
Air
1 and 5
Correct Answer. c
(48).
20/79
(49).
Nitrous oxide
Blue
Entonox
Cyclopropane
Orange
Ethylene
Red
Brown
Air (medical)
Carbon dioxide
Correct Answer. c
(50).
pH of the Thiopentone Na is
a. 11.5
b. 10.5
c. 9.5
d. 8.5
Solution. Ans-50: (b) 10.5
Ref: Pharmacology for Anesthesia and Intensive Care-104.
Sol :
Thiopentone is the sulphur analog of the oxybarbiturate pentobarbitone. It is formulated as the sodium salt and presented as a pale
yellow powder. The vial contains sodium carbonate and nitrogen in place of air.
These two measures are designed to improve the solubility of the solution. Sodium carbonate reacts with water forming sodium
bicarbonate resulting in a strongly alkaline solution (pH 10.5) favoring the water soluble enol form which is more desirable as
preparation.
The 2.5% solution is stable for many days and should be bacteriostatic due to its alkaline pH.
Correct Answer. b
21/79
(51).
(52).
22/79
(53).
(54).
40 year old man met motor vehicle catastrophe came to hospital in an hour severe maxillo facial trauma PR 120 / min BP - 100 / 70 mm
hg sPo2 - 80% with oxygen . which was the immediate management required
a. Intravenous acess
b. Orotracheal intubation
c. Naso tracheal intubation
d. Tracheostomy
Solution. Ans-54: (d) Tracheostomy
Ref:Sabiston Textbook of Surgery, 18thed
Sol:
After all critical issues in the primary survey have been addressed, a full head-to-toe secondary survey is undertaken, with the goal
of carefully examining the entire patient and identifying all injuries. The primary survey is conducted according to the mnemonic ABCDE:
airway, breathing, circulation, disability, exposure.
Airway
The crucial first step in managing an injured patient is securing an adequate airway.
Mechanical removal of debris and the chin-lift or jaw-thrust maneuver, both of which pull the tongue and oral musculature forward
from the pharynx, are often useful in clearing the airway of less severely injured patients.
However, if there is any question about the adequacy of the airway, if there is evidence of severe head injury, or if the patient is in
profound shock, more definitive airway control is necessary and appropriate.
Endotracheal intubation must be donerapidly, under the assumption of cervical spine instability, and in a fashion that does not
induce increased intracranial pressure (ICP) in patients with head injury.
Intubation is best accomplished by a technique borrowed from surgical anesthesia, known as rapid-sequence induction.
In rapid-sequence induction the patient is given a fast-acting anesthetic agent, followed by a neuromuscular blocking agent.
This combination of deep sedation andmuscular relaxation allows careful intubation without cervical hyperextension and with
minimal physiologic impact.
The technique can be used with a number of different pharmacologic agents, depending on the knowledge and preferences of the
individual practitioner. It is incumbent on the individual responsible for the procedure to be fully aware of the dosage, risks, and
indications associated with the agents chosen.
Excessive ventilation must be avoided after intubation, particularly in a hypovolemic patient because excessive ventilation will
increase mean intrathoracic pressure and compromise cardiac filling.
Although nasotrachealintubation had been widely suggested as a central modality for emergency airway control in the past, it should
now be used only rarely in the initial management of an injured patient.
Nasotracheal intubationhas a number of drawbacks, and the goal of safe endotracheal intubation with cervical spine precautions can
better be accomplished by orotracheal intubation after rapid-sequence induction.
In a few patients endotracheal intubation is either impractical or impossible, and a surgical airway is required.
Indications for a surgical airway include massive maxillofacial trauma, anatomic distortion as a result of neck injury, and inability to
visualize the vocal cords because of the presence of blood, secretions, or airway edema.
Actual tracheotomy may be indicated in select patients, such as those with laryngeal injuries.
Either surgical procedure may be preceded by needle cricothyroidotomy with jet insufflation to improve oxygenation and allow the
surgical procedure to be performed in more orderly fashion.
Correct Answer. d
23/79
(55).
What is the reason that an infant can breathe while suckling breast milk
a. Small wide tongue
b. High place larynx
c. Small pharynx
d. Short soft palate
Solution. Ans-55: (b) High place larynx
Ref:Read the text below
Sol:
The newborns larynx is located so much higher in its throat than that of an adult that the opening (covered by the epiglottis) is
above the stream of milk and the baby can breathe and eat at the same time without choking.
At about three years of age, the larynx moves down into the throat along with the back of the tongue which is fastened to it
Correct Answer. b
(56).
Opioid effects on respiratory rate and rhythm include all the following except
a. Decreased respiratory rate
b. Irregular respiratory rate
c. Cheyne-Stokes breathing patterns
d. Increased respiratory pauses
Solution. Ans-56: (c) Cheyne-Stokes breathing patterms
Ref:Read the text below.
Sol:
A Cheyne-Stokes respiratory pattern consists of periods of increasing hyperventilation alternating with apnea. The rate of ventilation
increases markedly and then declines until apnea occurs.
This pattern repeats in a rhythmic fashion.
Cheyne-Stokes respiration usually occurs after a cerebral anoxic event and reflects brain damage. Opioids do not cause this respiratory
pattern.
Correct Answer. c
(57).
Factors that increase the magnitude of opioid-induced respiratory depression include all the following except
a. Increased age
b. Concomitant use of benzodiazepines
c. Decreased hepatic blood flow
d. Increased clearance with decreased volume of distribution
Solution. Ans-57: (d) Increased clearance with decreased volume of distribution
Ref:Read the text below.
Sol:
An increased clearance with a decreased volume of distribution will decrease the half-life of any opioid and, therefore, all the opioids
properties will be of shorter duration including respiratory depression.
When opioids are combined with any other respiratory depressant, the effects are synergistic. In addition the magnitude of respiratory
depression will increase with bolus injections of narcotics, increased age, and decreased hepatic blood flow.
Correct Answer. d
24/79
(58).
(59).
Which of the following inhaled agents has been shown to be mutagenic in humans ?
a. Enflurane
b. Halothane
c. Isoflurane
d. None of the above
Solution. Ans-59: (d) None of the above
Ref:Read the text below.
Sol:
No inhaled agents havebeen shown to be mutagenic in humans. Halothane and nitrous oxide have been found to be weakly mutagenic
in in vitro testing.
Correct Answer. d
(60).
25/79
(61).
(62).
(63).
Intravenous midazolamis indicated for procedural sedation (often in combination with an opioid, such as fentanyl), for preoperative
sedation, for the induction of general anesthesia, and for sedation of ventilatedpatients in critical careunits.
Midazolam is superior to diazepamin impairing memory ofendoscopy procedures, but propofolhas a quicker recovery time and a
better memory-impairing effect.
It is the most popular benzodiazepine in the intensive care unit (ICU) because of its short elimination half-life, combined with its
water solubility and its suitability for continuous infusion.
Correct Answer. c
26/79
(64).
(65).
Contact granuloma, also known as a contact ulcer, is a condition where an ulcer is found in the vocal folds.
The most common cause of the condition is sustained periods of increased pressure on the vocal folds, and is commonly seen in
people who use their voice excessively.
Gastroesophageal reflux diseaseis also thought to be a contributing factor in the development of contact ulcers.
Correct Answer. a
(66).
Barotrauma can affect the external, middle, or inner ear. Middle ear barotrauma (MEBT) is the most common being experienced by
between 10% and 30% of divers and is due to insufficient equilibration of the middle ear.
External ear barotrauma may occur on ascent if high pressure air is trapped in the external auditory canaleither by tight fitting
SCUBA equipment or ear wax.
Inner ear barotrauma (IEBT) though much less common than MEBT shares a similar mechanism.
Mechanical trauma to the inner ear can lead to varying degrees of conductiveand sensorineural hearing lossas well as vertigo
Correct Answer. b
27/79
(67).
Chromosomalsyndromes (rare)
Congenital cholesteatoma- squamous epitheliumis normally present on either side of the tympanic membrane. Externally, within the
external auditory meatusor ear canaland internally within the middle ear. Within the middle ear the simple epithelium gradually
transitions into ciliated pseudostratified epithelium lining the Eustachian tubenow known as the pharyngotympanic tubebecoming
continuous with the respiratory epitheliumin the pharynx. The squamous epithelium hyperplasia within the middle ear behaves like an
invasive tumourand destroys middle ear structures if not removed.
Inflammatory
o Suppurative labyrinthitis
o Meningitis
o Mumps
o Measles
o Viral
o Syphilis
Ototoxicdrugs
o Aminoglycosides(most common cause; e.g., tobramycin)
o Loop diuretics(e.g., furosemide)
o Antimetabolites(e.g., methotrexate)
Salicylates(e.g., aspirin)
Correct Answer. b
(68).
Compression or rarefaction of the air in the external auditory canalexcites nystagmus when there is an erosion of the otic capsule, so
long as the labyrinth remains capable of functioning.
28/79
(69).
CSF discharging from the nose is known as CSF rhinorrhoea. Cerebrospinal fluid is a clear colorless fluid that bathes the brain and
spinal cord, cushioning them against trauma.
In fact in literal terms the brain and spinal cord floats in the cerebrospinal fluid. The specific gravity of brain is only 4% of that of
CSF, hence it could float easily in the CSF.
The high pressure leaks are commonly encountered in the cribriform area. This is due to the fagility and unique anatomy in this area
i.e. (prolongation of the subarachnoid space along the olfactory filaments).
The leak during these conditions functions as a safety valve alleviating the increased intracranial pressure. These high pressure
leaks are associated with slow growing tumors and 1/4 of them have hydrocephalus.
Pituitary neoplasms are the most common type of intracranial tumor found, next common are the posterior cranial fossa lesions.
Direct invasion of the skull base is not the usual mechanism of this leak.
Closure of these leaks may worsen the condition of the patient if the causative lesion is left untreated.
Correct Answer. b
(70).
29/79
(71).
The main artery of the tonsil is the tonsillar branch of the facial artery which enters the tonsil near its lower pole by piercing the
superior constrictor just above the styloglossus muscle. Other arteries supplying the tonsil are lingual artery through its dorsal lingual
branches, ascending palatine branch of facial artery, and ascending pharyngeal vessels.
Venous drainage occurs through the para tonsillar vein, and the vessels also pass through to the pharyngeal plexus or facial vein
after piercing the superior constrictor.
Lymphatic vessels from the tonsil pierce through the buccopharyngeal fascia and pass to the upper deep cervial group of nodes,
particularly to the jugulodigastric group.
Correct Answer. a
(72).
Quinsy otherwise also known as peritonsillarabscess is a collection of pus in the peritonsillar space between the superior constrictor
and capsule of the tonsil. It is usually unilateral, and commonly affects adolescent males.
Pathophysiology:
Infection usually starts in the crypta magna from where it spreads beyond the confines of the capsule causing peritonsillitis initially, and
peritonsillar abscess later.
Another proposed mechanism is necrosis and pus formation in the capsular area, which then obstructs the weber glands, which then
swell, and the abscess forms.
Correct Answer. a
30/79
(73).
Is commonly over the point of maximum bulge. It can also be made at the junction between a horizontal imaginary line drawn from
the base of the uvula to the anterior pillar and a vertical imaginary line drawn along the anterior pillar.
After incison is made a sinus forceps is introduced to complete the drainage procedure.
Six weeks after I&D tonsillectomy is performed in this patient to prevent further rucurrence. This is known as interval tonsillectomy.
Some authors prefer to do tonsillectomy immediatly on a quinsy patient. This is known as Hot tonsillectomy.
Correct Answer. d
(74).
Palpable, usually nonfluctuant tender mass below the angle of the mandible ++++
Stridor +++
31/79
(75).
A 65 year old male presents with cervical lymphadenopathy with recurrent epistaxis. Most likely cause is
a. Angiofibroma
b. Ca Nasopharynx
c. Rhabdomyosarcoma
d. None
Solution. Ans-75: (b) Ca Nasopharynx
Ref: Readthe text below
Sol:
CA NASOPHARYNX
Clinical Features:
- Painless cervical lymphadenopathy : 60%
(commonest Jugulodigastric)
- Epistaxis and nasorespiratory symptoms : 40%
- Audiological symptoms (Tinnitus, otalgia, Deafness) : 30%
- Neurological symptoms : 20% all cranial nerves except 1,2 and 7,8 can be involved
(Most commonly: V, VI, IX, X)
Correct Answer. b
(76).
(77).
Congenital syphilis
(here stapes footplate is hypermobile, so even small pressure changes in
ear, cause excessive movement of stapes footplate & excessive
stimulation of utricular macule)
Correct Answer. c
32/79
(78).
Chemotherapy
Diabetes
Ear pain- felt deep inside the ear and may get worse when moving head
Hearing loss
Fever
Trouble swallowing
Voice loss
Treatment
The goal of treatment is to cure the infection. Treatment often lasts for several months, because it is difficult to treat the bacteria and
reach an infection in bone tissue.
Antibiotics that are effective against the microorganism are given for long periods of time. They may be given through a vein
(intravenously), or by mouth. Antibiotics should be continued until scans or other tests show that inflammation has gone down.
Occasionally, surgery to remove dead or damaged tissue (surgical debridement) in the skull is needed.
Correct Answer. d
33/79
(79).
Keratosis obturans is
a. Foreign body in external auditory canal
b. Desquamated epithelial cell+Cholesterol
c. Cholesterol crystals surrounded by calcium
d. Wax in external auditory canal
Solution. Ans-79: (b) Desquamated epithelial cell+Cholesterol
Ref: Readthe text below
Sol:
Keratosis obturans: is accumulation of desquamated keratin in the external auditory meatus. This should be differentiated from primary
auditory canal cholesteatoma which is characterized by invasion of squamous tissue from the external ear canal into a localized area of
bone erosion.
Keratosis obturans commonly occur in young patients.
Clinical features:
1. Severe ear pain
2. Mild / moderate conductive hearing loss
3. Associated bronchitis / sinusitis - common
Management:
1. Surgical removal under G.A.
2. Canal plasty is helpful in recurrent cases
3. Mastoidectomy should be performed in cases with primary cholesteatoma of external canal.
Correct Answer. b
(80).
Atticoantral disease, in whichthe perforation is located in the eardrum at the attic region, and is typically associated with the
development of cholesteatoma.
Atticoantral disease is alsoassociated with a higher risk of major complications, e.g. brain abscess and other intracranial infection.
Correct Answer. a
34/79
(81).
Treatment of choice for Perforation in pars flaccid of the tympanic membrane with cholesteatoma is :
a. Myringoplasty
b. Modified Radical Mastoidectomy
c. Antibiotics
d. Radical mastoidectomy
Solution. Ans-81: (b) Modified Radical Mastoidectomy
Ref: Readthe text below
Sol:
Modified Radical Mastoidectomy is surgery to eradicate disease of the middle ear cavity and mastoid process, in which the mastoid and
epitympanic spaces are converted into an easily accessible common cavity by removing the posterior and superior external canal walls
Feature
Safe
Unsafe
1. Discharge
2. Perforation
3. Polyps
4. Cholesteotoma
5. Complication
Copious, odourless
Central
Pale coloured
Absent
Rare
Scanty, foul-smelling
Attic or marginal
Fleshy
Present
Common
Correct Answer. b
(82).
Treatment of choice for CSOM with vertigo and facial nerve palsy is :
a. Antibiotics and labyrinthine sedative
b. Myringoplasty
c. Immediate mastoid exploration
d. Labyrinthectomy
Solution. Ans-82: (c) Immediate mastoid exploration
Ref: Readthe text below
Sol:
CSOM with vertigo and facial nerve palsyis a emergency situation immediate mastoid exploration is indicated
Correct Answer. c
(83).
35/79
(84).
Endoscopic surgery through Intranasal approach is used for surgery of all organs except
a. Lacrimal gland
b. Cerebellum
c. Pituitary gland
d. Optic nerve
Solution. Ans-84: (b) Cerebellum
Ref:Dhingra 4th ed pg 373
Sol:
Indications
1. Chronic bacterial sinusitis unresponsive to adequate medical treatment.
2. Recurrent acute bacterial sinusitis.
3 . Polypoid rhinosinusitis (diffuse nasal polyposis) .
4. Fungal sinusitis with fung<11 ball or nasal polypi.
5. Antrochnanal polyp.
6. Mucocele of frontoethmoid or sphenoid sinus.
7. Control of epistaxis is by endoscopic cautery.
8. Removal of foreign body from the nose or sinus.
9. Endoscopic se ptoplasty.
Advanced Nasal Endoscopic Techniques
1. Removal of benign tumours, e.g. inverted papillomas or angiofibromas.
2. Orbital abscess or cellulitis management.
3. Dacryocystorhinostomy.
4 Repair of CSF leak.
5. Pituitary surgery.
6. Optic nerve decompress ion.
7. Orbital decompression for Graves disease.
8. Control of posterior epistaxis (endoscopic clipping of sphenopalatine artery).
9. Choanal atresia.
Correct Answer. b
(85).
Post- lingually deafened adults are good candidates.Results are not so good in pre-lingually deaf adults unless they had been
receiving aural-oral training forcommunication .
Criteria for children.
Auditory deprivation , i.e. lack of auditory stimulus in the early developmental period causesdegenerative changes in central auditory
pathways. Anearly auditory stimulation by cochlear implants can prevent it. Now implants can be used at an age as early as 12 months.
implants can be used in both pre-lingualy or postlingually deafened infants and children. The criteria are:
(a) Bilateral profound or severe to profound hearing Loss
(b) Minimal or no benefit from hearing aid
(c) No medical contraindication
(d) Willingness and support of family to enrol the child for post-implant training programme
Intracochlear placement of the electrode(s) into the scala tympani is superior to extracochlear placementover the promontory or
round window .
Correct Answer. a
36/79
(86).
Early cases of post-traumatic CSF rhinorrhoeaare managed conservatively by placing the patient in the semi-sitting position,
avoiding blowing of nose, sneezing and straining. Prophylactic antibiotics are also administered to prevent meningitis.
Persistent cases of CSF rhinorrhoea are treated surgically by nasal endoscopic or intracranial approach. Nasal endoscopic approach
is useful for leaks from the frontalsinus, cribriform plate, ethmoid or sphenoid sinuses
Correct Answer. d
(87).
It lies behind the pharynx between the buccopharyngeal fascia covering pharyngeal constrictor musc les and the pre vertebral
fascia.
The space is divid ed into two late ral compartments (spaces of Gillette) by a fibrous raphe .
Each lateral space contains retropharyngealnodes which usually disappear at 3-4 years of age.
Parapharyngeal space communicates with the retropharyngea l space. Infection of retropharyngeal space can pass down behind the
oesophagus into the mediastinum .
Prevertebral space.
It lies between the vertebral bodies posteriorly and the prevertebral fascia anteriorly. It extends from the base to skull of coccyx.
Abscess of this space produces a midline bulge in contrast to abscess of retropharyngeal space which causes unilateral bulge.
ACUTE RETROPHARYNGEAL ABSCESS
Aetiology
It is commonly seen in children below 3 years. It is the result of suppuration of retropharyngeal lymphnodes secondary to infection in
the ade noids , nasopharynx, posterior nasal sinuses or nasal cavity.
In adults, it may result from penetrating injury of posterior pharyngealwall or cervical oesophagus.
Rarely, pus from acute mastoiditistracks along the undersurface of petrous bone topresent as retropharyngeal abscess.
Clinical Features
1. Dysphagia and difficultyin breathing are prominent symptoms as the abscess obstructs the air and food passages.
2. Stridor and croupy cough may be present.
3. Tonicollis. The neck becomes stiff and the head is kept extended.
4. Bulge in posterior pharyngeal wall. Usually seen on one side of the midline .
Radiograph of soft tissue lateral view of the neck shows widening of prevertebral shadow and poss ibly even the presence of gas
Treatment
Incision and drainage of abscess . Thisis usually done without anaesthesia as there is risk of rupture of abscess during intubation.
Child is kept supine with head low. Mouth is opened with a gag. A vertical incision IS given in the m.ost fluctuant area of the abscess.
Suction should always be available to prevent aspiration of pus.
Tracheostomy. A large abscess may cause mechanical obstruction to the airway or lead to la ryngeal oedema.
CHRONIC RETROPHARYNGEAL ABSCESS
Cl inical Features
Patient may complain of discomfort in throat. Dysphagia,though present, is not marked. Posterior pharyngeal wallshows a fluctuant
swelling centrally or on one side ofmidline. neck may show tuberculous lymph nodes. Incases with caries of cervical spine, X-rays are
diagnostic
Correct Answer. b
37/79
(88).
Adenoid cystic carcinoma, formerly known as cylindromas, also present with a slowly growing asymptomatic parotid mass.
These tumours are characterised by early perineural spread and have a propensity for late recurrence, often to bone or lung,even up
to 20 years following an apparent cure.
Correct Answer. b
(89).
Adrenaline is added to Lignocaine to prolong its effect and decrease its absorption into blood stream in a ratio of
a. 1 : 50,000
b. 1 : 100,000
c. 1 : 200,000
d. 1 : 500,000
Solution. Ans-89: (b) 1 : 100,000
Ref: Bailey and Loves, 25th edn. Pg. 1387.
Sol :
Along with local anesthetics, adrenaline 1 in 100,000 or phenylephrine 1 in 20,000 is used for infiltration, nerve blocks and spinal
anesthesia. Reasons are :
Duration of anesthesia is prolonged
Systemic toxicity of local anesthetic is reduced.
Correct Answer. b
(90).
Bupivacaine
a. Cause depolarization of nerve membranes
b. Has a shorter duration of action than lignocaine
c. Is unsuitable for intrathecal use
d. Is contraindicated for intravenous regional anesthesia (IVRA)
Solution. Ans-90: (d) Is contraindicated for intravenous regional anesthesia (IVRA)
Ref: KD Tripathi--357.
Sol :
Bupivacaine is widely used in obstetric analgesia, both spinally and epidurally.
Onset is relatively slow, and may take 30 minutes for a full effect when used epidurally, but it has long duration of action lasting up to
10 hours after a nerve block.
Maximum safe dose with or without adrenaline is 2 mg/kg, maximum 150 mg in any 4 hours.
Bupivacaine is contraindicated in IVRA as it is more prone to prolong QTc interval and induce ventricular tachycardia or cardiac
depression.
Correct Answer. d
38/79
(91).
A phencyclidine derivative; produces an anesthetic state frequently called dissociative anesthesia which
implies that the patient is detached from their surroundings; vivid hallucinations are common during
recovery (emergence delirium) and can be minimized by concurrent use of benzodiazepines (e.g.
midazolam).
Systemic Effects
IOP, ICT; may be dangerous for hypertensives and in ischemic heat disease; since heart rate, BP
cardiac output are well-maintained even in shocked patients, it is useful in emergency surgery; laryngeal
reflexes are better maintained and bronchodilatation occurs; it increase salivation.
Advantages
Ketamine can also be administered by IM injection even when venous access is difficult.
Common procedures undertaken with ketamine anesthesia include lower leg surgery including
manipulation of fractures), gynaecological surgery (e.g. dilatation and curettage and other minor surgical
procedures), drainage of abscesses, debridement of burns, change of dressings.
Correct Answer. a
(92).
Athlete after surgery using succinylcholine cant move both limbs because
a. Psuedocholinesterase deficiency
b. Undiagnosed muscular dystrophy
c. Phase II Sch block
d. Due to fasciculation produced by succinyl choline as a side affect
Solution. Ans-92: (a) Psuedocholinesterase deficiency
Ref: Morgan Clinical Anesthesiology4th ed.
Sol:
Prolonged paralysis from succinylcholinecaused by abnormal pseudocholinesterase (atypical cholinesterase) should be treated with
continued mechanical ventilation until muscle function returns to normal
The dibucaine number is proportional to pseudocholinesterase function and independent of the amount of enzyme. Therefore,
adequacy of pseudocholinesterase can be determined in the laboratory quantitatively in units per liter (a minor factor) and qualitatively
by dibucaine number (the major factor).
Correct Answer. a
39/79
(93).
All of the following agents can be given for induction of anaesthesia in children Except:
a. Halothane
b. Servoflurane
c. Morphine
d. Nitrous oxide
Solution. Ans-93: (c) Morphine
Ref: Read the text below
Sol:
Morphine should not be used in infants specially those less than 6 months of age.Morphine is also not commonly recommended in
older children(3-10 years) of age
Most commonly used method for inducing gaseous anaesthesia is with O2 with or without N2O and either halothane or sevoflurane
Halothane is well tolerated in children, in which the risk of halothane induced hepatitis on repeated administration is small
Enflurane and isoflurane are more pungent and not recommended
Sevo flurane, if a available is the agent of choice Nitrous oxide particularly useful because of the speed of induction, absence of
cardiovascular and respiratory depression, its rapid on set and offset powerful analgesic action.
Correct Answer. c
(94).
A post dental extraction patient presents with swelling in posterior one third of the sternocliedomastoid, the tonsil is pushed medially.
Most likely diagnosis is
a. Retopharyngeal ascess
b. Parapharyngeal abscess
c. Ludwig angina
d. Vincent angina
Solution. Ans-94: (b) Parapharyngeal abscess
Ref: Readthe text below
Sol:
A parapharyngeal abscess is a deep neck abscess treated with antibiotics and surgical drainage.
The parapharyngeal (pharyngomaxillary) space is lateral to the superior pharyngeal constrictor and medial to the masseter muscle.
This space connects to every other major fascial neck space and is divided into anterior and posterior compartments by the styloid
process.
The posterior compartment contains the carotid artery, internal jugular vein, and numerous nerves. Infections in the parapharyngeal
space usually originate in the tonsils or pharynx, although local spread from odontogenic sources and lymph nodes may occur.
Abscess swelling can compromise the airway. Posterior space abscess can erode into the carotid artery or cause septic
thrombophlebitis of the internal jugular vein (Lemierre syndrome).
Correct Answer. b
(95).
Enflurane is best avoided as nephrotoxic levels of fluoride ions have been just after 3.5 MAC hours.
Isoflurane, Sevoflurane, desflurane and halothane result in little or no increase in fluoride levels and are preferred
Correct Answer. b
40/79
(96).
Opioid analgesia is achieved at a specific blood level for each patient for a given pain intensity.
Patients with severe pain typically continue to report pain until the analgesic blood level reaches a certain concentration above
which the patient experiences analgesia and the severity of pain rapidly diminishes.
That point is referred to as the minimum effective analgesic concentration (MEAC). Small increases above this point produce a large
increase in analgesia.
Intercostal and epidural anesthesia can additionally improve respiratory function following thoracic and upper abdominal operations
and encourage early ambulation.
Epidural and possibly spinal anesthesia reduce the incidence of thromboembolism following hip surgery and attenuate the
hypercoagulation state following vascular procedures.
A long-acting agent such as 0.5% ropivacaine (45 mL), injected two levels above and below the thoracotomy incision, typically
provides excellent pain relief. These blocks may be done under direct vision intraoperatively or via the standard technique
postoperatively.
Intercostal or paravertebral nerveblocks improve postoperative arterial blood gases and pulmonary function tests and shorten
hospital stay.
Alternatively, a cryoanalgesia probe may be used intraoperatively to freeze the intercostal nerves (cryoneurolysis) and produce longlasting anesthesia; unfortunately, maximum analgesia may not be achieved until 2448 h after the cryoanalgesia procedure.
(97).
The inferior nasal concha (Inferior Turbinated Bone) is one of the turbinates in the nose. It extends horizontally along the lateral wall
of the nasal cavity [Fig. 1] and consists of a laminaof spongy bone, curled upon itself like a scroll.
Each inferior nasal concha is considered a facial pair of bones since they arise from the maxillae bones and projects horizontally into
the nasal cavity.
The paired inferior nasal conchae are separate bones (i.e., they are not part of the ethmoid bone) instead articulates with ethmoid
and form part of the lateral walls of the nasal cavity
Correct Answer. c
41/79
(98).
systemic steroids
Correct Answer. a
(99).
42/79
(100).
Unilateral blood stained nasal discharge in a child of three years, old is most probably may be due to
a. Sinusitis
b. Dental infection
c. Viral rhinitis
d. A neglected foreign body
Solution. Ans 100: (d) A neglected foreign body
Ref Read the text below
Sol:
Common nasal FBs include hair beads, toy parts, paper, and food [1,11]. Nasal FBs are usually asymptomatic.
Symptomatic patients may present with unilateral nasal occlusion and fetid, purulent, or blood-stained nasal discharge.
The FB usually can be seen with anterior rhinoscopy after suctioning purulent secretions. Radiographs are of limited diagnostic
value because most FBs are radiolucent.
Correct Answer. d
(101).
Appearance of fever with rigor in a person with otitis media should make you suspect
a. Cerebellar abscess
b. Extradural abscess
c. Lateral sinus thrombosis
d. Apex petrositis
Solution. Ans 101: (c) Lateral sinus thrombosis
Ref Read the text below
Sol:
Although seldom encountered in the practice of modern otology, lateral sinus thrombosis (LST) and other intracranial complications
of otitis media still occur
The intracranial complications of otitis media include purulent meningitis, extradural or peridural abscess, LST, brain abscess and
otitic hydrocephalus. Respiratory mucosa, intact boney walls and protective granulations provide natural defense barriers within the
middle ear; complications occur when these are overcome. The spread of infection through the natural defenses can occur by
osteothrombosis, bone erosion and when present along preformed pathways.
Classic symptoms of LST include a "picket fence" fever pattern; chills; progressive anemia (especially with beta-hemolytic strep);
and, symptoms of septic emboli, headache and papilledema may indicate extension to involve the cavernous sinus. The Toby-Ayer test is
measured by monitoring the CSF pressure during a lumbar puncture. No increase in CSF pressure during external compression of the
internal jugular vein on the affected side, and an exaggerated response on the patent side, is suggestive of LST.
Correct Answer. c
(102).
Shaheen described Woodruff's plexus as an arterial plexus formed by anastomosis between pharyngeal, posterior nasal,
sphenopalatine and posterior septal arteries.
Microdissection and histological studies have proved Woodruff's plexus to be venous in origin.
Bleeding from the blood vessels of Woodruff's plexus could result in a slow but prolonged ooze. Since these blood vessels have no
muscle walls, hemostasis is poor. Post nasal packing will have to be resorted to in rare cases to stop bleeding.
Correct Answer. c
43/79
(103).
Correct Answer. b
(104).
Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma that occurs in the epithelial lining of the nasopharynx.
Among head and neck cancers, NPC has the highest propensity for developing distant metastases.
Histologies of NPC range from well-differentiated squamous carcinoma (WHO type I), to non-keratinizing squamous carcinoma
(WHO type II), to lympho-epithelial carcinoma (WHO type III), where non-keratinizing squamous carcinoma cells are mixed with
numerous benign lymphocytes.
Type III cancers are regarded as having the highest response to treatment, but also the greatest propensity for developing distant
micrometastatic spread.
Due to the anatomical location of the disease, NPC is typically not treated with surgical resection; rather concurrent
chemoradiotherapy is the preferred approach.
Correct Answer. c
44/79
(105).
(106).
Laryngeal spasm induced during intubation can be prevented by the following drugs except :
a. Fentanyl
b. Local anesthetic spray
c. Rofecoxib
d. Diltiazem
Solution. Ans-106: (c) Rofecoxib
Ref.: Paul AK. Anesthesia, 5th pg. 178
Sol :
Endotracheal intubation should always be done when the jawmuscles are relaxed and laryngeal reflexes are absent. This can be achieved
in various ways.
Deep general anesthesia employing inhalational anesthetics.
Intravenous anesthetic agent combined with muscle relaxants (suxamethonium, gallamine, tubocurarine)
Local anesthesia 4% lignocaine sprayed into larynx and down the trachea.
Reflex responses to laryngoscopy, intubation and extubation responses minimized by ?
Fentanyl, alfentanyl
Lignocaine, IV or inhalation
Vasodilator
Premedication with clonidine or mivazerol.
Esmenol
Induction with propofol
Verapamil, nifedipine, diltiazem
Enalapril, captopril
Correct Answer. c
45/79
(107).
(108).
Reversal of non-depolarising muscle relaxants action is done with the help of:
a. Atropine and neostigmine
b. Atropine and glycopyrrolate
c. Atropine and vecuronium
d. Neostigmine and edrophonium
Solution. Ans-108: (d) Neostigmine and edrophonium
Ref.:Paul AK Anesthesia, 5th ed. Pg 170
Sol :
Common antagonists to non-depolarizing relaxants :
Neostigmine anticholinesterase drug given IV, very slowly to counteract the action of non-depolarising muscle relaxants (0.5 2.5 m).
In order to counteract adverse effects (excessive salivary and bronchial secretion, bronchospasm and contraction of gut) atropine should
always be given, at least 5 min before neostigmine.
Endrophonium
Short acting synthetic anticholinesterase
Its anticurare action is due to its depolarizing action along with its direct action on motor end plate.
Atropine should be administered beforehand to combat muscarinic effects.
Correct Answer. d
(109).
Gutzmann pressure test ( external downward pressure on the thyroid cartilage will often evoke normal sounding voice) was positive.
46/79
(110).
The posterior group (sometimes the posterior ethmoid sinus) drains into the superior meatusabove the middle nasal concha;
sometimes one or more opens into the sphenoidal sinus.
The middle group (sometimes the middle ethmoid sinus) drains into the middle meatusof the noseon or above the bulla ethmoidalis.
The anterior group (sometimes the anterior ethmoid sinus) drains into the middle meatusof the noseby way of the infundibulum.
Correct Answer. b
(111).
It runs vertically from the anterior nasal spine upwards to the junction of bony and cartilagenous dorsum of nose.
Correct Answer. b
(112).
Correct Answer. c
47/79
(113).
(114).
Mastoid infection which erodes through the outer cortex of bone results in :
a. Sub-periosteal abscess
b. Epidural abscess
c. Perichondritis
d. Lateral sinus thrombosis
Solution. Ans-114: (a) Sub-periosteal abscess
Ref.:Read the text below
Sol :
Mastoid infection which erodes through the outercortex of bone results in sub-periosteal abscess.
Correct Answer. a
(115).
48/79
(116).
The position adopted for tonsillectomy is also adopted for this procedure (Rose Position) :
a. Direct laryngoscopy
b. Bronchoscopy
c. Tracheostomy
d. Indirect laryngoscopy
Solution. Ans-116: (c) Tracheostomy
Ref.:Dhingra -382, 292
Sol :
The position adopted for tonsillectomy is also adopted for Tracheostomy (Rose Position).
The position of patient during tonsillectomy is Rose position i.e. patient lies supine with head extended by placing a pillow under
shoulders.
In tracheostomy also patient lies in the same position.
Rose position is also used for Adenoidectomy.
Correct Answer. c
(117).
Cardiac or central nervous system toxicity may result when standard lignocaine doses are administered to patients with circulatory
failure. This may be due to the following reason :
a. Lignocaine concentration is initially higher in relatively well perfused tissues such as brain and heart.
b. Histamine receptors in brain and heart get suddenly activated in circulatory failure
c. There is a sudden outburst of release of adrenaline, noradrenaline and dopamine in brain and heart
d. Lignocaine is converted to a toxic metabolite due to its longer stay in the liver.
Solution. Ans-117: (a) Lignocaine concentration is initially higher in relatively well perfused tissues such as brain and heart.
Ref.:Read the text below
Sol :
Lignocaine has very high first pass metabolism.
Its metabolism is dependent on hepatic blood flow. Its t1/2 increases in patients with CHF.
It is initially distributed rapidly to well perfused tissues (like brain and heart) but action terminates rapidly due to redistribution.
Correct Answer. a
(118).
Thiopentione
a. 2.5% in aqueous solution has a pH of approximately 10.5
b. Is metabolized only by the kidney
c. Is an oxybarbiturate
d. Is unstable in solution if it is kept for 24 hrs
Solution. Ans-118: (d) Is unstable in solution if it is kept for 24 hrs
Ref.:Lees anesthesia, 13th edn. Pg. 150-156.
Sol :
Barbiturates
Oxybarbiturate pentobarbital and methohexital
Thiobarbiturates thiopental and thiamylal
Sodium thiopentone(also known as thiopental or pentothal) is prepared by dissolving a yellowish powder in sterile water to provide a
2.5% solution (i.e. 25 mg/ml). In this concentration 20 mls of solution will contain 500 mg.
The solution should be used within 24 hours of preparation and kept cool.
The solution is alkaline with a pH of greater than 10, and can be irritating and painful if accidentally injected into tissues. Because of
the alkalinity, thiopentone should not be mixed in the same syringe as other drugs, as it may cause formation of a cloudy precipitate and
inactivate the drug.
Correct Answer. d
49/79
(119).
(120).
(121).
50/79
(122).
(123).
(124).
51/79
(125).
(126).
Remifentanil is
a. Useful for short painful procedures
b. Metabolized by plasma esterase
c. Equipotent as fentanyl
d. All of above.
Solution. Ans-126: (d) All of above.
Ref.:Goodman and Gilman 11th ed. Pg. 572
Sol :
Remifentanil is shortest acting opioid due to its metabolism by plasma esterases.
Due to its short duration of action, it is indicated for short term painful procedures.
Intravenous bolus dosing is not practical because of short duration of action, rather it is administered by constant i.v. infusion.
Potency is equal to fentanyl and similiarly it can also cause post operative muscle rigidity.
Correct Answer. d
(127).
Which focal length in the objective piece of microscopes commonly used for ear surgery :
a. 100 mm
b. 250 mm
c. 450 mm
d. 950 mm
Solution. Ans-127: (b) 250 mm
Ref.:Read the text below
Sol :
250 mm of focal length in the objective piece of microscope is commonly used for ear surgery.
Focal length of objective lens
For ear surgery : 200 mm/250 mm
For nose/Paranasal sinus surgery : 300 mm
For laryngeal surgery : 400 mm
Correct Answer. b
52/79
(128).
A 5-year old patient is scheduled for tonsillectomy. On the day of surgery he had running nose, temperature 37.5 C and dry cough.
Which of the following should be the most appropriate decision for surgery :
a. Surgery should be cancelled
b. Can proceed for surgery if chest is clear and there is not history of asthma
c. Should get X-ray chest before proceeding for surgery
d. Cancel surgery for 3 weeks and patient to be on antibiotic
Solution. Ans-128: (d) Cancel surgery for 3 weeks and patient to be on antibiotic
Ref.:Read the text below
Sol :
Contraindications to Tonsillectomy
Correct Answer. d
(129).
(130).
Condition where pulsatile tumor is found in external auditory meatus which bleed on touch :
a. Cholesteatoma
b. Polyp
c. Glomus tumor
d. Malignancy middle ear
Solution. Ans-130: (c) Glomus tumor
Ref.:Dhingra /107
Sol :
In Glomus tumor, pulsatile tumor is found in external auditory meatus which bleed on touch.
When tumor presents as a polyp :
Profuse bleeding from the ear either spontaneously or an attempts to clean it
Examination reveals a red, vascular polyp filling the meatus
Correct Answer. c
53/79
(131).
(132).
(133).
A young man having pheochromocytoma has BP of 188/92 mm Hg and a hematocrit of around 50%. Pulmonary function tests and renal
functions are normal. His catecholamines are elevated. Which of the following drugs should not be included in the anesthesia protocol ?
a. Desflurane
b. Fentanyl
c. Halothane
d. Midazolam
Solution. Ans-133: (c) Halothane
Ref.:Read the text below
Sol :
Halothane sensitizes the heart to arrhythmogenic action of catecholamines.
In pheochromocytoma, there are elevated levels of catecholamines.
Therefore, halothane should not be used in patients with pheochromocytoma.
Correct Answer. c
54/79
(134).
If ketamine is the only agent used in reducing a dislocated shoulder, its actions will include
a. Analgesia
b. Bradycardia
c. Hypotension
d. Respiratory depression
Solution. Ans-134: (a) Analgesia
Ref.:Read the text below
Sol :
Ketamine is a powerful analgesic agent.
It increases blood pressure, intraocular pressure and intracranial tension.
It does not depress CVS and respiratory system.
Correct Answer. a
(135).
The most important adverse effect of i.v. administration of large dose of an amide anesthetic is
a. Bronchoconstriction
b. Hepatic damage
c. Renal failure
d. Seizures
Solution. Ans-135: (d) Seizures
Ref.:Read the text below
Sol :
The most important adverse effect of i.v. administration of large dose of an amide anesthetic is seizures.
Correct Answer. d
(136).
Which of the following drugs has a high surface activity and vasoconstrictor actions that reduce bleeding in mucus membranes ?
a. Bupivacaine
b. Cocaine
c. Lidocaine
d. Procaine
Solution. Ans-136: (b) Cocaine
Ref.:Read the text below
Sol :
All local anesthetics are vasodilators except cocaine. It possesses vasoconstrictor activity.
Cocaine also has good surface activity.
Correct Answer. b
55/79
(137).
Bosselated round to oval sessile tumor projected from subperiosteal or endosteal surface of cortex.
Composed of sclerotic well formed bone
Most common site : Skull & facial bones
MC site of ivory osteoma is Frontal-ethmoidal region
Usually solitary; multiple osteomas seen in Gardeners syndrome.
Generally slow growing and asymptomatic but can cause obstruction of sinus cavity, impinge on brain or eye.
Not premalignant and do not transform into Osteosarcoma.
Generally no treatment given but excision may be done if causes cosmetic problems.
Correct Answer. a
(138).
Delayed speech in a 5-year old child with normal motor and adaptive development is most likely due to :
a. Mental retardation
b. Cerebral palsy
c. Kernicterus
d. Deafness
Solution. Ans-138: (d) Deafness
Ref.:Dhingra / 148
Sol :
Delayed speech in a 5-year old child with normalmotor and adaptive development is most likely due to deafness.
Correct Answer. d
(139).
56/79
(140).
(141).
(142).
57/79
(143).
(144).
Endolymph is present in :
a. Scala media
b. Scala vestibule
c. Scala tympani
d. Cochlear aqueduct
Solution. Ans-144: (a) Scala media
Ref.:Read the text below
Sol :
Scala vestibule and scala tympani are filled with perilymph.
Scala media filled with endolymph.
Correct Answer. a
(145).
Meningitis may be associated with acute or subacute/chronic infection. Acute otitis media is the most common cause of meningitis.
Extradural granulation tissue or frank pus may be found.
In adults and children, meningitis in the setting of chronic suppurative otitis media may be secondary to the direct extension of
infection through the dura, through a previous stapedectomy site, or through a cholesteatoma-induced labyrinthine fistula.
Correct Answer. a
58/79
(146).
What is the largest size endotracheal tube that will pass readily through the lumen of a size3 laryngeal mask airway (LMA)?
a. 6.00 mm Internal Diameter (ID).
b. 6.50 mm ID.
c. 7.00 mm ID.
d. 7.5 mm ID.
Solution. Ans-146: (a) 6.00 mm Internal Diameter (ID).
Ref:Read the text below
Sol :
A size 3 or 4 LMA will allow up to a size 6.00 mm ID endotracheal tube to be passed without an introducer.
1. An adult size 5 LMA takes a 7.0 ID Endotracheal tube (ETT).
In paediatric practice:
1. A size 2.5 LMA will allow the passage of a 5.0 mm ID ETT or a 4.0mm outside diameter flexible bronchoscope with an ETT loaded on it.
2. A size 1 LMA will allow the passage of a 3.5 mm ID ETT which will protrude 8 cm from grille using ETT adaptor
Correct Answer. a
(147).
The following capnograph trace was obtained from an intubated patient who was ventilated using a circle system with the absorber on.
The trace is most compatible with:
The tube is in the right main bronchus. - Under these circumstances the left lung is poorly ventilated (ie has a low overall V:Q ratio)
and a long overall time constant.
Thus the initial plateau represents gas exchange in the right lung and the later plateau that in the left.
Correct Answer. d
59/79
(148).
A lower Segment Caesarean Section (LSCS) can be carried out under all the following techniques of anesthesia except :
a. General anesthesia
b. Spinal anesthesia
c. Caudal anesthesia
d. Combined Spinal Epidural anesthesia
Solution. Ans-148: (c) Caudal anesthesia
Ref:Read the text below
Sol :
Regional anaesthesia is the technique of choice for elective caesarean section.
Techniques are :
Spinal anaesthesia
Epidural anaesthesia
Combined spinal epidural anaesthesia
The proportion of Mothers being delivered under general anaesthesia by caesarean section depends on many factors. It is gradually
falling.
The primary advantages of GA for Caesarian section is the reliability and rapidity of onset of a state in which the operation is
performed.
Caudal anaesthesia is unpopular because of the risk of introducing needle passing through the mother's sacrum and rectum and into
fetal presenting parts.
Correct Answer. c
(149).
The most appropriate circuit for ventilating a spontaneously breathing infant during anesthesia is :
a. Jackson Rees 'modification of Ayress' T Piece
b. Mapleson A or Magill's circuit
c. Mapleson C or Water to and fro canister
d. Bains circuit
Solution. Ans-149: (a) Jackson Rees 'modification of Ayress' T Piece
Ref:Read the text below
Sol :
Jackson Ree's modified it and added a bag for monitoring and IPPV. (Maplesion F)
The main advantage of the T-piece technique is the absence of resistance to expiration, a factor of crucial importance in small
children.
Efficacy of systems with spontaneous respiration.
A > D &E > C > B
Although A is more efficaeous but E is more suitable for infants.
Efficacy of systems with IPPV
D&E>B>C>A
Correct Answer. a
60/79
(150).
A 30 year old layd is to undergo surgery under intravenous regional anesthesia for her left 'trigger finger' Which of he following should
not be used for this patient :a. Lignocaine
b. Bupivacaine
c. Prilocaine
d. Liignocaine + Ketorolac
Solution. Ans-150: (b) Bupivacaine
Ref:Read the text below
Sol :
Intravenous regional anaesthesia or Bier's block is used for producing intense surgical anaesthesia for short surgical procedures of the
forearm and hand.
An esmarch bandage or an orthopaedic pneumatic splint is used to compress the arm of the forearm
The anaesthetic is inserted on the dorsum of the hand through an intravenous catheter.
(151).
A 21 year old lady with a history of hypersensitivity to neostigmine is posted for an elective caesarean section under general anesthesia.
The best muscle relaxant of choice in this patient should be :a. Pancuronium
b. Atracurium
c. Rocuronium
d. Vecuronium
Solution. Ans-151: (b) Atracurium
Ref:Read the text below
Sol :
Neostigmine is ananticholinesterase. Its action prevents the metabolism of acetylcholine by the enzyme acetylcholinesterase. This
increases the concentration of Acetylcholine in the synaptic cleft and leads to development of action potential.
This causes the muscles paralysed by the muscle relaxants to return back to their normal contractile state.
Neostigmine is usually requiredafter long acting muscle relaxants have been used. to hasten recovery at the end of operation.
Mivacurium is the shortest acting competitive blocker therefore it does not need reversal.
Correct Answer. b
(152).
The main mechanism by which local anesthetics exert their effect is blockade of :a. Receptor operated sodium channels.
b. N type of calcium channels
c. Voltage operated sodium channels
d. Voltage operated potassium channels.
Solution. Ans-152: (c) Voltage operated sodium channels
Ref:Read the text below
Sol :
The primary mechanism of action of local anesthetics is blockade of voltage gated sodium channels in the nerve axons.
Correct Answer. c
61/79
(153).
Correct Answer. b
(154).
The etiology of nasal septal perforations can be classified into the following 4 main categories: traumatic, iatrogenic,
inflammatory/malignant, and inhalant related.
Most traumatic or iatrogenic perforations result from (1) mucosal lacerations on corresponding sides of the septum with exposure of
the underlying cartilage or (2) a fracture of the cartilaginous septum.
Perforation occurs because the cartilage relieson the overlying mucoperichondrium for its blood supply and nutrients. Traumatic
injuries may be self-induced from nose picking or may result from facial trauma.
Iatrogenic causes include nasal surgical procedures and nasal intubation or nasogastric tube placement; prior septal surgery is the
most common cause of septal perforations.
Septal hematoma, if not identified and treated early, may also result in perforation secondary to loss of cartilaginous structure,
infection, and/or abscess formation.
Infectious and inflammatory etiologies, including tuberculosis, syphilis, Wegener granulomatosis, and sarcoidosis, should always be
considered in the differential diagnosis.
Correct Answer. b
62/79
(155).
Four types of local anesthetic have been reported as possibly causing methemoglobinemia: prilocaine, benzocaine, lidocaine, and
tetracaine.
Correct Answer. a
(156).
Which of the following local anesthetics is more likely to cause allergic reactions?
a. Lidocaine
b. Bupivacaine
c. Procaine
d. Ropivacaine
Solution. Ans 156: (c) Procaine
Ref Read the text below
Sol:
A cause of local toxicity is allergic reaction to para-aminobenzoic acid (PABA). These reactions range from urticaria to anaphylaxis.
PABA is a metabolic product of the degradation of Ester class of local anesthetics, such as Procaine (Novocaine), Benzocaine, and, to
a lesser degree, amide class anesthetics such as Lidocaine, and Prilocaine. It is also a metabolic by-product of Methylparaben, a
preservative in multi-dose vials of Lidocane.
When allergic response to injected anesthetics does occur, it is most likely due to the ester class local anesthetics. The amide class of
local anesthetics is far less likely to produce allergic reaction
Correct Answer. c
(157).
All of the following statements about the action of local anesthetics are true, except:
a. A resting nerve is lesser sensitive than one that is repetitively stimulated
b. Small nerve fibres are more susceptible that the large nerve fibres
c. Somatic fibres are more susceptible than the autonomic fibres
d. Temperature sense is blocked earlier than the deep pressure sense.
Solution. Ans 157: (c) Somatic fibres are more susceptible than the autonomic fibres
Ref Read the text below
Sol:
Autonomic nerve fibresare smaller and are more susceptible and are blocked earlier than the somatic fibres.
In the somatic fibres also, sensory fibres are more susceptible than the motor.
Some L.A.s areeven motor sparing e.g. Bupivacaine, so are preferred in obstetrics as the mother can actively cooperate in the
delivery.
Among the somatic afferentsorder of blockade is: pain-temperature sense-touch sensation-deep pressure sense.
Correct Answer. c
63/79
(158).
Lignocaine is an antiarrhythmic(as for ventricular fibrillation) and a local anesthetic (as for spinal and epidural anesthesia).
Lignocaine is not useful in convulsions, rather it can cause convulsions in higher doses.
Correct Answer. d
(159).
Chloroprocaine is the shortest acing L.A. as it is rapidly metablolized by plasma pseudocholinesterases and has plasma half-life of
just 25 seconds.
Correct Answer. b
(160).
Lignocaine is commonlymixed with prilocaine to make an Eutectic Mixture for Local Anesthesia (EMLA) to anesthetize the intact
skin.
Rest of surface acting local anesthetics can anesthetize only the mucus membrane and abraded skin and not the intact skin.
Correct Answer. c
64/79
(161).
Bupivacaine is indicated for local anaesthesiaincluding infiltration, nerve block, epidural, andintrathecal anaesthesia. Bupivacaine
often is administered by epidural injection before total hiparthroplasty. It also is commonly injected to surgical wound sites to reduce
pain for up to 20 hours after the surgery.
Sometimes, bupivacaine is co-administered with epinephrine to prolong the duration of its action, fentanyl for epidural analgesia,
or glucose.
Compared to other local anaesthetics, bupivacaine is markedly cardiotoxic. However, adverse drug reactions (ADRs) are rare when it
is administered correctly. Most ADRs relate to administration technique (resulting in systemic exposure) or pharmacological effects of
anesthesia, however allergic reactions can rarely occur.
Systemic exposure to excessive quantities of bupivacaine mainly result in central nervous system (CNS) and cardiovascular effects
CNS effects usually occur at lower blood plasmaconcentrations and additional cardiovascular effects present at higher
concentrations,though cardiovascular collapse may also occur with low concentrations.
CNS effects may include CNS excitation (nervousness, tingling around the mouth, tinnitus, tremor, dizziness, blurred vision,seizures)
followed by depression (drowsiness, loss of consciousness, respiratory depression and apnea). Cardiovascular effects
includehypotension, bradycardia, arrhythmias, and/or cardiac arrest some of which may be due to hypoxemia secondary to respiratory
depression.
Correct Answer. a
(162).
Non-opioid Agents
This class of agents can be further broken down into barbiturates, benzodiazepines and other drugs such as etomidate, ketamine,
propofol, etc.
Propofol
Propofol is a substituted phenol which also has rapid onset and short duration of action. It can be used in a similar manner to
barbiturates and etomidate as an induction agent. The usual dose for this is 1.5-2.5 mg/kg which produces unconsciousness within a
minute.
Propofol is rapidly redistributedlike the barbiturates but it is also rapidly metabolized by the body. The fast redistribution is
reponsible for its initial short duration of action. The rapid metabolism means that, unlike the barbiturates, propofol does not build up in
the tissues. As a result, propofol can be used as a continuous infusion for maintenance of unconsciousness without prolonging wake-up.
Propofol comes as a soybean emulsion. This emulsion does support bacterial growth, so care must be taken to maintain the drugs
sterility and to use freshly prepared drug. This emulsion is also responsible for some pain on injection.
Propofol will decrease blood pressure by dilating blood vessels, but otherwise has few other side effects.
Correct Answer. a
65/79
(163).
Sevoflurane has largely replaced halothane and isoflurane as an inhalation anesthetic of choice because:
a. Induction of anesthesia is achieved more rapidly and smoothly
b. Recovery is more rapid
c. It has low post- anesthetic organ toxicity
d. All of the above
Solution. Ans 163: (d) All of the above
Ref Read the text below
Sol:
Sevoflurane has several properties which make it potentially useful as a day case anaesthetic.
Following induction of anaesthesia with propofol, awakening from sevoflurane is faster compared to isoflurane, faster or similar
compared to propofol and comparable (in the majority of studies) to desflurane. Subsequent recovery and discharge is generally similar
following all agents.
Sevoflurane may also be used to induce anaesthesia, which is generally well-received and causes less hypotension and apnoea
compared to propofol. When used as a maintenance anaesthetic, the incidence of postoperative nausea and vomiting after sevoflurane is
comparable to other inhaled anaesthetics, but this complication appears more common after inhaled inductions.
The tolerability and low solubility of sevoflurane facilitate titration of anaesthesia and may reduce the need for opioid analgesia,
which in turn may limit the occurrence of nausea and vomiting.
Correct Answer. d
(164).
Which of the following inhaled anesthetics causes centrally mediated sympathetic activation leading to a rise in blood pressure and heart
rate?
a. Desflurane
b. Sevoflurane
c. Nitrous oxide
d. Isofurane
Solution. Ans 164: (a) Desflurane
Ref Read the text below
Sol:
Desflurane is a halogenated ether inhalation general anaestheticagent with low solubility in blood and body tissues, and
approximately one-fifth the potency of isoflurane.
The pharmacodynamic properties of desflurane generally resemble those of isoflurane; thus, it produces dose-dependent depression
of the central nervous and cardiorespiratory systems, and tetanic fade at the neuromuscular junction. The alveolar equilibration of
desflurane is rapid (90% complete at 30 minutes compared with 73% for isoflurane). Both desflurane and isoflurane are distributed to
various tissues to a similar extent.
(165).
Which of the following agents is used to accelerate recovery from the sedative actions of intravenous benzodiazepines?
a. Naloxone
b. Flumazenil
c. Ketamine
d. Fomepizole
Solution. Ans 165: (b) Flumazenil
Ref Read the text below
Sol:
Flumazenil is of benefit in patientswho become excessively drowsy after benzodiazepines are used for
either diagnostic or therapeutic procedures.
It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on theGABAA receptor.
There are many complications that must be taken into consideration when used in the acute care setting.
Correct Answer. b
66/79
(166).
This is because barbiturates induce microsomal enzymes and increase the porphyrin synthesis.
Correct Answer. a
(167).
Induction of anesthesia is more with injectable agents (e.g. thiopentone) rather than gaseous and volatile agents.
The more the blood solubility, the less rapid is the induction and recovery MAC is the minimal alveolar concentration required to a
painful stimulus (surgical incision) in 50% individuals.
It is a measure of potency of the anesthetics. Depth of anesthesia would be more with more anesthetic conc. In brain.
Correct Answer. c
(168).
67/79
(169).
Halothane is a volatile liquid which is nonirritant and noninflammable,it is a potent anesthetic but not a good analgesic or muscle
relaxant.
But it potentiates the competitive neuromuscular blockers. Halothane causes relatively greater depression of respiration.
It suppresses pharyngeal, laryngeal and cough reflexes and dilate the bronchi, so preferred in asthmatics.
(170).
Thiopentone sodium is an ultrashort acting barbiturate,reason of being ultrashort acting is its high redistribution in the body.
Redistribution means after initial distribution in the organs of high blood flow like brain (producing instant action within 15 sec),it
gets redistributed in the less vascular organs like muscle & fat, terminating its action (consciousness regained within 10 min.)
(171).
Balanced anesthesia means using a variety of agents to decrease the dose of each agent and get optimum analgesia, amnesia and
skeletal muscle relaxation.
68/79
(172).
(173).
(174).
Tympanoplasty is now popularized in our country due to its great success rate with less complication. Outcome depends on selection
of patients.
Central perforation with wide margin is a wide margin is a good candidate for tympanoptasty operation.
Ear should be dry for at least 3 months. Eustachian tube must be patent for good result.In our study post auricular incision was
given in all cases. It is easy to perform and the view of site under microscope is wide.
For the beginner it is a better approach. Other incision like endaural or permeatal can also be given.
Temporals facial was used in every case because it is thin but tough, can be obtained in same incision, has low O2 demand i.e. low
metabolic rate, after healing look like normal TM.
Correct Answer. c
69/79
(175).
Propofol is a short-acting, intravenouslyadministered hypnotic agent. Its uses include the induction and maintenance of general
anesthesia, sedation for mechanically ventilated adults, and procedural sedation.
Chemically, propofol is unrelated to barbiturates, and has largely replaced sodium thiopental(Pentothal) for induction of anesthesia
because recovery from propofol is more rapid and "clear" when compared with thiopental.
Propofol is not considered an analgesic, so opioids such asfentanyl may be combined with propofol to alleviate pain.
Due to its amnestic effects and appearance as a white liquid, propofol has been humorously dubbed "milk of amnesia" by doctors
Correct Answer. b
(176).
Indicate the intravenous anesthetic, which causes minimal cardiovascular and respiratory depressant effects:
a. Propofol
b. Thiopental
c. Etomidate
d. Midazolam
Solution. Ans 176: (c) Etomidate
Ref Read the text below
Sol:
Etomidate is a short acting intravenous anaesthetic agent used for the induction of general anaesthesia and for sedationfor short
procedures such as reduction of dislocated joints andcardioversion.
The use of etomidate infusions for sedation of critically ill patients in intensive care units has been associated with increased
mortality, which is due to suppression of steroid synthesis (both glucocorticoids and mineralocorticoids) in the adrenal cortex, which
sometimes leads to death due to an adrenal crisis; Thus, etomidate contributes to critical illnessrelated corticosteroid insufficiency.
Seizure-like activity is occasionally seen with anesthetic induction. In the absence of concurrent EEG monitoring, it is difficult to
ascribe this to cortical activity. Myoclonic movement originating at the spinal cord level is often a likely mechanism.
Excitatory phenomena, and epileptiform movements and EEG activity may be observed during induction. Etomidate consistently
increases the amplitude of somatosensory evoked potentials (in contrast to most anaesthetic agents).
Correct Answer. c
(177).
Ketamine has a wide range of effects,including analgesia, anesthesia, hallucinations, elevated blood pressure, and bronchodilation.
Ketamine is primarily used for the induction and maintenance of general anesthesia, usually in combination with some sedative drug.
Other uses include sedation in intensive care, analgesia (particularly in emergency medicine), and treatment of bronchospasm. It is
also a popular anesthetic in veterinary medicine.
Correct Answer. b
70/79
(178).
(179).
Ether is not only an excellent analgesic but also very good skeletal muscle relaxant.
Halogenated ethers such as Halothane, Isoflurane and Desflurane are not so good analgesics and relaxants.
So with their use in surgery, additional analgesics and muscle relaxants are required.
Correct Answer. a
(180).
Halothane sensitizes the heart, so that if Adrenaline is used concurrently, tachyarrhythmias occur.
Correct Answer. d
71/79
(181).
(182).
(183).
Which of the following intravenous anesthetic agent is the drug of choice in patients of shock:
a. Ketamine
b. Thiopentone
c. Althesin
d. Propanidid
Solution. Ans 183: (a) Ketamine
Ref Read the text below
Sol:
Ketamine is uniquein this regard that it raises the blood pressure hence the anesthetic of choice in shock.
Correct Answer. a
72/79
(184).
Cytotoxic drugs
Nitrogen mustard
Cisplatin
Analgesics
Salicylates
Indomethacin
Chemicals
Alcohol
Tobacco
Marijuana
Carbon monoxide poisoning
Antimalarials
Quinine
Chloroquin
Kanamycin:
Kanamycin has a propensity to cause profound cochlear hair cell damage, marked high-frequency hearing loss, and complete
deafness.
The damaging effect is primarily to the cochlea, while the vestibular system is usually spared injury.
Kanamycin has limited clinical use today. As with neomycin, parenteral administration is generally not recommended.
Correct Answer. c
(185).
Bone-anchored hearing aid is based on bone conduction. Bone-anchored hearing aids use a surgically implanted abutment to
transmit sound by direct conduction through bone to the inner ear, bypassing the external auditory canal and middle ear.
The device is composed of three main parts: a titanium implant, an external abutment, and a sound processor. The titanium
prosthesis is surgically embedded into the skull with a small abutment exposed outside the skin.
BAHA- bone anchored hearing aid will be given to hearing impaired individulas where conentional hearing aids can not be given like in
bilateral Anotia, EAC atresia, discharging ear, EAC stenosis. Its is a specialised device which is surgically fitted partly on to mastoid bone
.
Correct Answer. b
73/79
(186).
Chronic rhinosinustis are defined as symptoms of sinusitis persist for more than
a. 2 weeks
b. 4 weeks
c. 6 weeks
d. 12 weeks
Solution. Ans-186: (d) 12 weeks
Ref:Read the text below
Sol :
CHRONIC RHINOSINUSTIS
When symptoms of sinusitis persist for more than 12 weeks Chronic State develops. Commonest cause is incomplete resolution of acute
episode.
Organism: Mixed aerobic & anerobic
Treatment (Medical line)
Correct Answer. d
(187).
(188).
74/79
(189).
(190).
(191).
Mucocelesmost likely occur as a result of obstruction of the ostium of a sinus with resultant accumulation of mucus and eventual
expansion of the sinus.
Some authors (the minority) believe that they represent a mucous retention cyst which gradually enlarges, eventually filling the
whole sinus .
Chronic non-invasive fungal sinusitis has also been associated with the formation of mucocoeles
The frontal sinus is particularly prone to developing a mucocoeles, and up to two-thirds of all mucocoeles occur there. The ethmoidal
sinuses are the next most common, whereas maxillary and sphenoidal sinuses are infrequently involved
Correct Answer. a
75/79
(192).
Radiation therapy for nasopharyngeal carcinomais usually administered in a procedure called external beam radiation.
For small nasopharyngeal tumors, radiation therapy may be the only treatment necessary.
In other situations, radiation therapy may be combined with chemotherapy
Correct Answer. c
(193).
(194).
Cochleovestibular impairmentwas evaluated, in relation to age, in a longitudinal follow-up study on a Dutch family with a DFNA9
trait caused by a Pro51Ser mutation in the COCH gene on chromosome 14q12-q13. Fourteen cases were genotyped.
The onset age of progressive impairment reported by the mutation carriers was between age 35 and 45 years. Pure-tone thresholds
deteriorated by about 2-7 dB per year (mean 3.8 dB per year) in a variable, often asymmetrical, fashion. One mutation carrier developed
recurrent episodes of vertigo accompanied by nausea and vomiting, resembling Mnire's disease.
DFNA9/COCH should be considered as a possible cause in patients developing combined progressive cochlear and vestibular
impairment, or suspected hereditary Mnire-like disease, from around middle age.
Correct Answer. d
76/79
(195).
(196).
Rhinosporidiosis and its causative pathogen Rhinosporidium seeberi have been known for over a hundred years.
Recent work included in this review are molecular biological classification of R.seeberiamong the hydrophilic organisms of the
former DRIP clade, establishment of a method for the purification of the developmental stages, and some aspects of the immunology
of R.seeberi with reference to mechanisms of immune evasion - antigenic variation, host immunoglobulin binding, immune deviation in
relation to the chronicity, recurrence and dissemination seen in rhinosporidiosis.
The mechanism of endospore release from the sporangium has been described. Some problems involved in the resolution of enigmas
that persist are briefly discussed.
Moreover, it shows morphological featuresresembling those of protozoa
Correct Answer. c
(197).
Tympanoplasty is most commonly performed for tympanic membrane perforations greater than :
a. 0 20% of the size of tympanic membrane.
b. 20 % 30% of the size of tympanic membrane.
c. 30 % 40% of the size of tympanic membrane.
d. 40 % 50% of the size of tympanic membrane.
Solution. Ans-197: (a) 0 20% of the size of tympanic membrane.
Ref.:Read the text below
Sol :
Tympanoplasty includesall procedures when the tympanic membrane is lifted from its position in the ear canal.
Tympanoplasty is most commonly performed for tympanic membrane perforations greater than 10 20% of the size of the entire
tympanic membrane.
Tympanoplasty alone or type 1 tympanoplasty denotes that the surgery is confined to the eardrum alone, and no manipulation of the
middle ear bones (ossicles) occurs.
Tympanoplasty that includes manipulation of the ossicles is defined as tympanoplasty with ossicular reconstruction, or
tympanoossiculoplasty.
Correct Answer. a
77/79
(198).
(199).
(200).
Test Answer
1.(b)
2.(a)
3.(d)
4.(a)
5.(b)
6.(c)
7.(a)
8.(c)
9.(c)
10.(a)
11.(a)
12.(a)
13.(a)
14.(a)
15.(d)
16.(a)
17.(c)
18.(a)
19.(d)
20.(a)
21.(a)
22.(a)
23.(b)
24.(c)
25.(c)
26.(b)
27.(b)
28.(a)
29.(b)
30.(c)
78/79
31.(a)
32.(a)
33.(a)
34.(d)
35.(b)
36.(a)
37.(b)
38.(c)
39.(b)
40.(c)
41.(d)
42.(d)
43.(b)
44.(a)
45.(d)
46.(c)
47.(c)
48.(a)
49.(c)
50.(b)
51.(a)
52.(b)
53.(c)
54.(d)
55.(b)
56.(c)
57.(d)
58.(d)
59.(d)
60.(d)
61.(c)
62.(a)
63.(c)
64.(c)
65.(a)
66.(b)
67.(b)
68.(a)
69.(b)
70.(d)
71.(a)
72.(a)
73.(d)
74.(b)
75.(b)
76.(c)
77.(c)
78.(d)
79.(b)
80.(a)
81.(b)
82.(c)
83.(d)
84.(b)
85.(a)
86.(d)
87.(b)
88.(b)
89.(b)
90.(d)
91.(a)
92.(a)
93.(c)
94.(b)
95.(b)
96.(d)
97.(c)
98.(a)
99.(b)
100.(d)
101.(c)
102.(c)
103.(b)
104.(c)
105.(c)
106.(c)
107.(c)
108.(d)
109.(b)
110.(b)
111.(b)
112.(c)
113.(a)
114.(a)
115.(a)
116.(c)
117.(a)
118.(d)
119.(b)
120.(b)
121.(a)
122.(b)
123.(d)
124.(b)
125.(d)
126.(d)
127.(b)
128.(d)
129.(b)
130.(c)
131.(a)
132.(b)
133.(c)
134.(a)
135.(d)
136.(b)
137.(a)
138.(d)
139.(c)
140.(c)
141.(d)
142.(b)
143.(c)
144.(a)
145.(a)
146.(a)
147.(d)
148.(c)
149.(a)
150.(b)
151.(b)
152.(c)
153.(b)
154.(b)
155.(a)
156.(c)
157.(c)
158.(d)
159.(b)
160.(c)
161.(a)
162.(a)
163.(d)
164.(a)
165.(b)
166.(a)
167.(c)
168.(b)
169.(d)
170.(b)
171.(d)
172.(a)
173.(c)
174.(c)
175.(b)
176.(c)
177.(b)
178.(a)
179.(a)
180.(d)
181.(c)
182.(a)
183.(a)
184.(c)
185.(b)
186.(d)
187.(c)
188.(a)
189.(a)
190.(d)
191.(a)
192.(c)
193.(a)
194.(d)
195.(b)
196.(c)
197.(a)
198.(c)
199.(d)
200.(c)
79/79