Non Modifiable Risk Factors

Modifiable Risk Factors

Havent had vaccineDrugs

for chicken
that suppress
pox
the immune system
Diseases that suppress the immune system
(e.g. Corticosteroids)
Treatment Modalities that suppress immune
system
(e.g.
HIV/AIDS)
(e.g. Chemotherapy)

Increased Suceptibility for Varicella

Environmental Factors ( Winter and EarlyMalnutrition

Spring)
Immunocompromised
(Imparied Immune System)

Exposure to Chicken Pox Varicella

Peak of through
the Disease
Reservoir
Decrease
(increase
Nutrition
occurrence)
for fighting a
Increased Suceptibility for Varicella

Increased Suceptibility for Varicella

CA: Varicella Zoster Virus (VZV)

Enters through the Respiratory tract and conjunctiva

Immunologic Mechanisms of the Body against Infection

(Increase in WBC, Fever)
Virus infects the mucosal tissue of the nose

Virus is earned w

Suppression of viral replication

Establishes an infection in the regional lymph nodes around t

Diffuse Viral Invasion

Possible reactivation Due to medication (e.g Corticosteroids), disease (AIDS), malnutrition and immunosuppression
Viral Proliferation through Replication occurs 2-4 days after initia

VZV causes vasculitis of the b

Primary Viremia on Post Infection for 4-6 days

Virus Migrates along the Sensory
Virus Nerves
Migrates along the Motor Nerves

Increase lev
Disperses to multiple organs of the body (2nd round of viral replication) e.g. live

Weakness, Headache, Malaise

Sensory Loss and Pain

Interce
Anorexia, Body Malaise, Fever

Development of the Skin Lesion

Prodromal Period 2
days before the rash
develops

Pre-eruptive Stage
(Body Malaise, Fever)

Head, Trunk (most

concentrated),
extremities, hairy
portion of the scaly,
throat

Progression of the
Lesion
Macule
Papule
Pustule
Vesicle
Crust or Scab

CELESTIAL MAP
Initial Lesions (red
papules become
milky and pus like
with in 4 days

Eruptive Stage

Host is capable of
transmitting virus

Initial Lesions (red

papules become
milky and pus like
with in 4 days

Lesions starts to
appear after 2-3 days

Rapid Progression in
6-8 hours of lesions

Lesions 1st appear on

cover areas then to
uncover ones
(centripetal)

By the 4th
Symptomatic Day,
lesions begin to dry
and new lesions do
not develop

Pruritus

Once the Lesion is not

crusted, it is no
longer contagious