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    5th Jan 17 Patho 04 Adrenals DR - Aznar

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    Nogra Carl
    This document discusses the adrenal gland. It describes the three zones of the adrenal cortex - the zona glomerulosa which produces mineralocorticoids like aldosterone, the zona fasciculata which produces glucocorticoids like cortisol, and the zona reticularis which produces sex hormones like estrogen. It also describes the adrenal medulla which produces catecholamines like norepinephrine. Several adrenal disorders are mentioned including Cushing's syndrome, Conn syndrome, and Addison's disease. Infectious diseases that can affect the adrenal glands like tuberculosis and meningococcal infections are also briefly discussed.

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    5th Jan 17 Patho 04 Adrenals DR - Aznar

    Uploaded by

    Nogra Carl
    14 views30 pages
    This document discusses the adrenal gland. It describes the three zones of the adrenal cortex - the zona glomerulosa which produces mineralocorticoids like aldosterone, the zona fasciculata which produces glucocorticoids like cortisol, and the zona reticularis which produces sex hormones like estrogen. It also describes the adrenal medulla which produces catecholamines like norepinephrine. Several adrenal disorders are mentioned including Cushing's syndrome, Conn syndrome, and Addison's disease. Infectious diseases that can affect the adrenal glands like tuberculosis and meningococcal infections are also briefly discussed.

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    5th Jan 17 Patho 04 Adrenals Dr.aznar

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    This document discusses the adrenal gland. It describes the three zones of the adrenal cortex - the zona glomerulosa which produces mineralocorticoids like aldosterone, the zona fasciculata which produces glucocorticoids like cortisol, and the zona reticularis which produces sex hormones like estrogen. It also describes the adrenal medulla which produces catecholamines like norepinephrine. Several adrenal disorders are mentioned including Cushing's syndrome, Conn syndrome, and Addison's disease. Infectious diseases that can affect the adrenal glands like tuberculosis and meningococcal infections are also briefly discussed.

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    14 views30 pages

    5th Jan 17 Patho 04 Adrenals DR - Aznar

    Uploaded by

    Nogra Carl
    This document discusses the adrenal gland. It describes the three zones of the adrenal cortex - the zona glomerulosa which produces mineralocorticoids like aldosterone, the zona fasciculata which produces glucocorticoids like cortisol, and the zona reticularis which produces sex hormones like estrogen. It also describes the adrenal medulla which produces catecholamines like norepinephrine. Several adrenal disorders are mentioned including Cushing's syndrome, Conn syndrome, and Addison's disease. Infectious diseases that can affect the adrenal glands like tuberculosis and meningococcal infections are also briefly discussed.

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    of 30

    Endocrinology

    PETER S. AZNAR, MD, FPSP, MHPE


    Adrenal Gland
    Adrenal Gland Cross Section
    Zona Glomerulosa Mineralocorticoids Aldosterone Increased Conn Syndrome
    Decreased Addisons Disease

    Adrenal Cushings
    Cortex Zona Fasiculata Glucorticoids Cortisol Increased Syndrome

    Decreased Addison's Disease


    Zona Reticularis Sex Hormones Estrogen Increased
    Decreased

    Adrenal Medulla Norepinephrine Vanillyl Mandelic Acid (VMA) Pheochromocytoma

    Dopamine Homovanillic Acid (HVA) Neuroblastoma


    Cushings Syndrome

    ACTH
    Increased = Cushings disease
    Decreased = Addisons disease
    Cushings Syndrome
    Normal Cushings
    Estrogen

    Estradiol- most potent


    Estriol- increase in pregnancy
    Estrone- increase in
    postmenopausal women
    Zona
    Glomerulosa Mineralocorticoids Aldosterone Increased Conn Syndrome
    Addisons
    Decreased Disease

    Adrenal Cushings
    Cortex Zona Fasiculata Glucorticoids Cortisol Increased Syndrome
    Addison's
    Decreased Disease
    Zona
    Reticularis Sex Hormones Estrogen Increased
    Decreased

    Vanillyl Mandelic Acid


    Adrenal Medulla Norepinephrine (VMA) Pheochromocytoma

    Dopamine Homovanillic Acid (HVA) Neuroblastoma


    Infectious Diseases of the Adrenal Gland

    - Tuberculosis (1855) Addisons Disease

    - N. meningitidis (1878) Waterhouse


    Friderichsen Syndrome

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