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Results From SAMHSA/CSAT's Evaluation of The Buprenorphine Waiver Program
Results From SAMHSA/CSAT's Evaluation of The Buprenorphine Waiver Program
Waiver Program
100%
90%
93%
80%
83%
70%
60%
50%
40%
30% 41%
33%
20%
10%
12%
0%
Heard of Willing to Sought a Provided Planned to
BUP Refer for Waiver Treatment Obtain
BUP Waiver
67% Prescribing*
Number of Physicians who Have
Received Waivers (in Thousands)
5.0
(Waivered Physician Survey)
4.5
4.0
3.5 52% Prescribing
3.0 (Addiction Physician Survey)
Practice Setting of
Waivered Physicians
1600
1400 Prescribing
1200
1000
800
600
400
200
0
2003
2005
2003
2005
2003
2005
2003
2005
2003
2005
2003 data are from the Addiction Physician Survey, 2005 data are from the Waivered Physician Survey
80,000 32%
63,204
60,000 34%
38%
40,000
20,000
0
Sept - Dec 2003 Jan - March 2005
Mean # of Patients/Physician 57 46
SD 6 147
Range 1-800 1-1011
2003 data are from the Addiction Physician Survey, 2005 data are from the Waivered Physician Survey
30,000
25,000
4,485
20,000 10,862
13,542
8,896 34,078
15,000
10,000 19,322
14,651 5,243
12,360 12,209 3,462 2,867
5,000 5,538
2,114
5,097 3,640 3,847 3,940
1,509
0
2003 2005 2003 2005 2003 2005 2003 2005 2003 2005
100%
Methadone Admissions to TEDS Sites
Percent of Patients Treated
60%
53% 56%
40%
50%
42%
35%
20% 29%
18%
0%
Female White Employed Some
Post-
* The Treatment Episode Data Set reports on admissions to facilities receiving Secondary
public funding. Admissions to private facilities are underrepresented. Education
60%
40%
20%
0%
New to New to Transitioned Addicted to Non-
Substance Medication- from Methadone Heroin Opioids*
Abuse Assisted
Treatment Treatment * In Patient Study, drug of abuse
By Length of Treatment
100% 4%
15% 12%
7% 22%
80%
19%
60% 41%
34%
40% 74%
0%
<=7 Days 8-30 Days >1 Month
N= 574 N= 581 N= 697
Very Effective Somewhat Effective
Not at All Effective Don't Know/No Response
*Views reported by physicians who also reported experience treating for that length of time
Physicians reported 217 patients with adverse reactions, out of a total 47,664
patients inducted (unweighted).
Poster Presented at
The College on Problems of Drug Dependence
June 20, 2005
1
Westat, Rockville, MD
2
Substance Abuse and Mental Health Services Administration,
Center for Substance Abuse Treatment, Rockville MD
The Gap Between Abuse & Treatment of
Painkillers (Non-heroin Opioids) is Large
and Has Grown Over Time
Procedures
Site Selection
• Drew random stratified sample of 400 physicians from CSAT’s
Buprenorphine Waiver Notification System in April 2004
• Physician/sites eligible to participate if prescribing;
67% reported that they were prescribing BUP
• 123 sites qualified and were willing to participate
(46% of prescribing physicians)
• Due to slow flow of new patients through sites, also included
purposive sample of 9 induction centers
– Induction centers specialize in induction of patient onto BUP
– After induction, patient transferred to other Waivered
physician for maintenance
Patient Recruitment
• Patient recruitment brochures mailed to each site had a unique
ID number
• Brochures consisted of 2 sections separated by perforation:
• Staff gave new patients one section with a toll-free telephone
number, description of the study, and an ID number
• Staff completed the second section with a checklist of
observable patient demographic characteristic and mailed
it to Westat
• Patients called Westat for interview at initiation of treatment,
with follow-up telephone interviews at 30 days and 6 months
• Telephone interviewers accepted interviews only from persons
with valid ID numbers
• Number of nonresponders determined by number of cards
returned without accompanying interview
• Participants received an incentive for each completed survey:
$40 for baseline, $50 for 30 day followup, and $60 for
6 month follow-up
• All instruments and procedures were reviewed and approved
by Westat’s Institutional Review Board and by the Office of
Management and Budget
100%
80%
60% 60%
60%
31%
40%
20% 9%
0%
New to New to Transitioned Addicted to
Substance Medication- from Non-Heroin
Abuse Assisted Methadone Opioids*
Treatment Treatment
Methadone Patients* & BUP Patient
Study Sample: Demographic Differences
100%
Methadone Admissions to TEDS Sites
Percent of Patients Treated
60%
53% 56%
40%
50%
42%
35%
20% 29%
18%
0%
Female White Employed Some
Post-
Secondary
*The Treatment Episode Data Set (TEDS) reports primarily on admissions to facilities
Education
receiving public funding. Admissions to private facilities are underrepresented.
Methadone Patients* & BUP Patient
Study Sample: Age Differences
5% 4%
100%
55+
Percent of Patients Treated
22% 45 to 54
24%
80% 35 to 44
25 to 34
Under 25
60% 26%
36%
Patient Study
40% respondents were
32% younger than
25% methadone patients
20%
in TEDS
10% 16%
0%
Methadone* BUP
Primary %
Opioid of Use* Frequency Sample 60% reported
Heroin 174 40% primarily using
Oxycodone 124 29% opioids other
Hydrocodone 74 17% than heroin in
Street Methadone 18 4% the 30 days prior
Multiple Rx Meds 10 2% to treatment.
Hydromorphone 9 2%
*The primary drug of abuse was
None Specified 8 2% determined by an item asking for the
Morphine 5 1% opioid used most often in the last
30 days. The primary drug of abuse
Rx Methadone 4 1% for 9% of the sample in a controlled
environment such as jail or inpatient
Fentanyl 3 1%
treatment in the 30 days prior to
Other 5 1% treatment was determined by the
drug with the longest lifetime use.
Other = Propoxyphene, Meperidine, Tramadol, Codeine, Opium
Primary Opioid Abused & Regular
Problematic Use of Other Opioids
300 Of those reporting heroin as
the primary drug of abuse,
66% also reported regular
250 abuse of other opioids for at
Other Opioids least one month.
(Primary) plus
Heroin
Number of Patients
Source: Substance Abuse and Mental Health Services Administration, Office of Applied Studies. National Survey
on Drug Use and Health Report: Nonmedical oxycodone users: A comparison with heroin users. January 21 2005.
BUP Patients Abusing Only
Non-heroin Opioids Differ from
Other Opioid Abuse Groups
Heroin Only Non-heroin Heroin & Non-
Opioids Only heroin Opioids
N=59 N=173 N=198
Female* 31% 50% 38%
White* 69% 98% 93%
40% Non-
96% Non-heroin 83% Heroin heroin
Only Only Only
Heroin &
Heroin Non-heroin Non-heroin
Only Opioid Only Opioids
N=59 N=173 N=198
Followup at 30 Days 86% 98% 95%
30 Day BUP Treatment Outcomes:
Treatment Retention at 30 Days
(Self-Reported)
100%
80%
60%
93% 95% 93%
40% retention retention retention
rate rate rate
20%
0%
Nonheroin Opioids Heroin & Non-heroin Heroin Only
Only Opioids
N= 169 N= 186 N= 51
20
15
10
5
0
Nonheroin Heroin & Non- Heroin Only
Opioids Only heroin Opioids
N= 169 N=188 N=51
12
10
8
6
4
2
0
Nonheroin Heroin & Non- Heroin Only
Opioids Only heroin Opioids
N= 168 N= 186 N= 51
(Self-Reported)
Abstinent from
All Drugs and
46% Abstinent
Alcohol from Alcohol and
16% 46% All Other Drugs
Taking
Opioids
Other 84% Abstinent
than
BUP from Opioids
14% Other than BUP
24% Using
Abstinent from Alcohol,
Opioids, Using Abstinent
Non-Opioid from All
Substances Other Drugs
• Few new patients moved through study sites May ‘04 – Feb ‘05