1st line mekanism sifat Ef-sa dosis Keterang

agent e an lain
Rifampici hambat Bakterici Pewarnaan Enzyme
n DNA- d cairan tbh inducer
dependen Hepatotoxi
t RNA c percepat
polymeras Flu-like metabolis
e symptoms me obat
Intermitte KB
n
Absorbs
sind.hepat
dihambat
orenal
foods &
PAS
INH Hambat Bakterici Neuritis Ditambah
sintesis d perifer piridoxin
as.micolat hepatotoxi utk
c mencega
h neuritis
perifer
PZA Blm bakterios Hepatotoxi > kuat
diketahui tatik c (icterus) dlm
Hambat suasana
ekskresi asam
as.urat
hiperurise
mia
Etambut Hambat bakterios Neuritis Kadar
ol sintesis tatik retrobulba dlm
metabolis r eritrosit
msel Color blind 1-2x
kuman Scotoma plasma
mati central/per obat
ifer dilepasin
dikit2
Tdk dpt
menemb
us sawar
otak, tapi
pd
meningiti
s TB bisa
capai
kadar
utuh