Generic &

Dose, Indication/Mechanisms of Drug Adverse/Side Effects Nursing Client

Brand Name, Rationale
& Formulation Action Drug Interaction Responsibilities Teaching
Classification

Generic: Tablets: 2.5 mg, 5 Indications: Adverse Effect: Assessment: >Advise patient to
mg, 10 mg take medication as
Amlodipine Angina pectoris due to coronary CNS: Dizziness, BEFORE:
directed, even if
artery Spasm, Chronic stable lightheadedness,
angina, alone or in combination headache, asthenia, Obtain patients *To indicate if the feeling well.
history to patient can have this >Take missed doses
with other agents, Essential fatigue, lethargy
allergy of medication. as soon as possible
hypertension, alone or in CV: Peripheral edema,
Brand: amlodipine. unless
combination with other arrhythmias
Assess vital *To obtain baseline almost time for
Norvasc antihypertensive, Dermatologic: Flushing,
signs before data. next dose; do not
rash
therapy. double doses.
GI: Nausea, abdominal
DURING: > Caution
Discomfort
Monitor *Drug can cause patient to change
Mechanism of Action:
Classification: patients BP, hypotension, careful positions slowly to
Inhibits the movement of calcium cardiac rhythm monitoring needed. minimize
Calcium Interactions:
ions across the membranes of *To assess hepatic orthostatic
channel-blocker Drug-drug Monitor intake
cardiac and arterial muscle cells; impairment. hypotension.
Antianginal Possible increased serum and output.
inhibits transmembrane calcium > Advise patient to
Drug levels and toxicity of AFTER:
flow, which results in the * To stop medication notify health care
Antihypertensive cyclosporine if Monitor vital
depression of impulse formation in if BP is < 90 mmHg professional if
taken concurrently. signs.
specialized cardiac pacemaker cells, or heart rate < 50 irregular heartbeats,
slowing of the velocity of Be alert for bpm. dyspnea, swelling
conduction of the cardiac impulse, adverse effect. *to establish proper of hands and feet,
depression of myocardial precautionary pronounced
contractility, and dilation of Nursing diagnosis: measures. dizziness, nausea,
coronary arteries and arterioles and >Acute pain related to constipation, or
peripheral arterioles; these effects increased oxygen hypotension
lead to decreased cardiac work, demand in cardiac occurs or if
decreased cardiac oxygen tissue. headache is severe
consumption, and in patients with >Risk for injury related or persistent.
vasospastic angina, increased to hypertension > Caution patient to
>Deficient knowledge
 delivery of oxygen to cardiac cells. related to drug therapy. wear protective
clothing and use
sunscreen to
prevent
photosensitivity
reactions.

Generic & Dose, Indication/Mechanisms Adverse/Side Effects Nursing Rationale Client

Brand Name, & Formulation of Drug Action Drug Interaction Responsibilities Teaching
Classification

Generic: Tablet{ as tartate) Indications: Adverse Effect: -Always -for baseline data -Inform
check patient about
Metoprolol 25mg Hypertension CV: Bradycardia patients -Drug can cause the side
50mg Acute MI Heart failure apicalpulse effects and
Angina Pectoris
hypotension, careful
100mg -Monitor BP monitoring needed. adverse
Brand: tablet, extended- -Store drug at effects of the
Side Effect: room medication.
Lopressor
release (as Mechanism of Action: CV: hypotension temperature. -To assess hepatic -Advise
succinate) Unknown. A selective GI: nausea and patient to
- Lab tests: Monitor impairment.
Classification: 25mg beta blocker that vomiting take it with
CBC, electrolytes, liver
50mg selectively blocks Respi: dyspnea & kidney function with meals.
Beta- adrenergic
100mg
Skin:rash -Tell patient to
blocking beta1 receptors; long-term therapy.
agents 200mg
report if
decreases cardiac
he/she feels
output, peripheral shortness of
resistance, and breath.
cardiac oxygen -Tell patient
consumption; and that
depresses rennin metoprolol is
secretion. not advisable
to
breastfeeding
mothers.
-Advise not to
withdrawn drug
abruptly.
Generic & Dose, Indication/Mechanisms Adverse/Side Effects Nursing Rationale Client
Brand Name, & Formulation of Drug Action Drug Interaction Responsibilities Teaching
Classification

Generic: Ordered: Indications: Adverse effect: Assessment:

LOSARTAN Give 50mg 1tab, OD Treatment of CNS: Headache, BEFORE: > Take drug without
hypertension, alone or in dizziness, syncope, Assess patients *To obtain baseline regard to meals.
Timing: combination with other insomnia health history. data. >Do not stop taking
Brand: 8 am antihypertensive CV: Hypotension *To obtain this drug without
Assess patients
Cozaar Agents. Dermatologic: Rash, precautionary consulting your health
blood pressure.
Duration: Treatment of diabetic urticaria, pruritus, measures care provider.
Assess patients *To know if the patient
unknown neuropathy with an alopecia, dry skin renal function. >Tell patient to take
Classification: elevated serum GI: Diarrhea, can have this drug at morning to
DURING: medication.
cardiovascular Other forms: creatinine and abdominal pain, prevent insomnia at
Monitor *To indicate renal
agent; angiotensin Tablets: 25 mg, 50 mg, proteinuria in patients nausea, constipation, night.
patients intake impairment
II receptor antagonist; 100 mg with type 2 (non dry mouth >Stop medication if
and output. *To avoid excessive
antihypertensive insulin-dependent) Respiratory: URI adverse reaction occur,
diabetes and a history of symptoms, cough, Administer urination at night. notify prescriber
hypertension sinus disorders drug at immediately.
Other: Back pain, daytime.
fever, gout, muscle AFTER:
Mechanism of Action: weakness Be alert for *to establish proper
Selectively blocks the adverse precautionary
binding of angiotensin II Interactions reaction. measures.
to specific tissue Drug-drug Monitor *To know if the patient
receptors found in the Decreased serum patients can sleep well.
vascular smooth muscle levels and sleeping
and adrenal gland; this effectiveness if taken pattern. Nursing Diagnosis:
action blocks the concurrently with >Risk for injury
vasoconstriction effect phenobarbital related to presence of
of the renin-angiotensin Losartan is converted hypertension
system as well as the to an active metabolite >Sleep deprivation
 release of aldosterone by cytochrome P450- related to drug induced
leading to decreased 3A4. Drugs that inhibit insomnia.
blood pressure. 3A4 (ketoconazole, >deficient knowledge
fluconazole, diltiazem) related to drug therapy.
may decrease the
antihypertensive
effects of losartan.

Generic &
Dose, Strength Indication/Mechanisms of Drug Adverse/Side Effects Nursing Client
Brand Name, Rationale
& Formulation Action Drug Interaction Responsibilities Teaching
Classification

Generic: Ordered: Indications: Adverse effects: Assessment: >Take drug 1 hr

Captopril give 50 mg 1tab Treatment of hypertension alone or CV: Tac hycardia , angina BEFORE: before or 2 hr after
every 8 hours via in combination with thiazide-type pectoris, MI, Raynaud's Assess patient *To know if the meals; do not take
NGT diuretics . syndrome, CHF, history patient can have this with food. Do not
Brand: Treatment of CHF in patients hypotension in regarding drug. stop without
Capoten Timing: unresponsive to conventional salt- or volume-depleted allergy to consulting your
8 am, 4 pm, 12 mn therapy; used with patients captopril *To obtain health care
diuretics and digitalis Dermatologic: Rash, Assess patients precautionary provider.
Classification: Duration: Treatment of diabetic nephropathy pruritus, pemphigoid-like renal function. measures. >Be careful of drop
Antihypertensive 6-12 hours Treatment of left ventricular reaction, scalded mouth Assess vital *To obtain baseline in blood pressure
dysfunction after MI sensation, exfoliative signs. data. (occurs most often
Other forms: dermatitis, DURING: with diarrhea,
Tablets: 12.5 mg, Mechanism of Action: photosensitivity, alopecia *To determine sweating, vomiting,
Monitor
50 mg, 100 mg Blocks ACE from converting GI: Gastric irritation, effectiveness of the dehydration); if
patients health
angiotensin I to angiotensin II, a aphthous ulcers, peptic drug. light-headedness or
status.
powerful vasoconstrictor, leading to ulcers, dysgeusia,cholesta *To assess for further dizziness occurs,
decreased blood pressure, decreased tic jaundice, hepatocellular Monitor renal impairment. consult your
aldosterone secretion, a small injury, anorexia, patients output. health care
increase in serum potassium levels, constipation AFTER: *To ensure patients provider.
and sodium and fluid loss; GU:Proteinuria, renal Monitor vital health condition. >Avoid over-the-
increased prostaglandin synthesis insufficiency, renal failure, signs. *to establish counter
also may be involved in the polyuria, oliguria, urinary Be alert for precautionary medications,
antihypertensive action. frequency adverse measures and especially cough,
Hematologic: reaction. management. cold, allergy
Neutropenia,
agranulocytosis,
thrombocytopenia,
hemolytic
anemia,pancytopenia
Other:Cough, malaise,
dry mouth,
lymphadenopathy
Interactions
Drug-drug
Increased risk of
hypersensitivity reactions
with allopurinol
Decreased
antihypertensive effects
with indomethacin
Increased captopril effects
with probenecid
Drug-food
Decreased absorption of
captopril with food
Drug-lab test
False-positive test for
urine acetone.
medications that
Nursing Diagnosis: may contain
>Risk for injury related ingredients that will
to underlying interact with ACE
condition. inhibitors.
>Ineffective protection >These side effects
related to drug induced may occur: GI
blood disorder. upset, loss of
>deficient knowledge appetite, change in
related to drug therapy taste perception,
mouth sores ,rash;
fast heart rate;
dizziness, light-
headedness.
>Report mouth
sores; sore throat,
fever, chills;
swelling of the
hands, feet;
irregular heartbeat,
chest pains;
swelling of the
face, eyes, lips,
tongue, difficulty
breathing.