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Nonselective α blockers have been a failure in the management of essential hypertension
Nonselective α blockers have been a failure in the management of essential hypertension
Atropine is a potent mydriatics but its slow and long lasting action is
undesirable for refraction testing. Though the pupil dilates in 3040
min, cycloplegia takes 13 hours, and the subject is visually
handicapped for about a week The substitutes attempt to overcome
these difficulties.
High dose of ACh given after atropine causes tachycardia and rise in BP
due to stimulation of sympathetic ganglia and release of catecholamines