6/11/2016 DrugInteractionsresultsMICROMEDEX

DrugInteractionResults
Frmacosseleccionados:Cipro(Ciprofloxacin),Dipyrone,Omeprazole,traMADolHCl
(TramadolHydrochloride)
Gravedad:Todo
Documentacin:Todo
InteractionType:Todo

DrugDrugInteracciones(Sincoincidencias)

Duplicacindeingrediente(Sincoincidencias)

DrugALERGIAInteracciones(Sincoincidencias)

DrugCOMIDAInteracciones(3)
Frmacos: Gravedad: Documentacin: Resumen:
CIPROFLOXACIN Good Concurrentuseof
CIPROFLOXACINand
CAFFEINEmayresultin
Moderate increasedcaffeine
concentrationsand
enhancedCNSstimulation.

CIPROFLOXACIN Good Concurrentuseof

CIPROFLOXACINand
DAIRYFOODSmayresult
Moderate indecreasedciprofloxacin
concentrations.

OMEPRAZOLE Good ConcurrentuseofPROTON

PUMPINHIBITORSand
CRANBERRYmayresultin
Moderate reducedeffectivenessof
protonpumpinhibitors.

DrugETANOLInteracciones(1)
Frmacos: Gravedad: Documentacin: Resumen:
TRAMADOLHYDROCHLORIDE Fair Concurrentuseof
Major ETHANOLandTRAMADOL
mayresultinanincreased
riskofrespiratory
depressionandexcessive
CNSdepression.

DrugLABORATORIOInteracciones(6)
Frmacos: Gravedad: Documentacin: Resumen:
OMEPRAZOLE Fair OMEPRAZOLEmayresult
Major inmayinterferewith
diagnosticinvestigationfor
neuroendocrinetumorsdue
toserumchromograninA
(CgA)levelsincreasewith
decreasesingastricacidity.

OMEPRAZOLE Good PROTONPUMP

INHIBITORSmayresultin
falsepositiveurine
Moderate screeningtestsfor
tetrahydrocannabinol(THC)
duetounknown.

OMEPRAZOLE Fair OMEPRAZOLEmayresult

inriskoffalsepositive
resultduetohyperresponse
Moderate ingastrinsecretion.

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CIPROFLOXACIN Good CIPROFLOXACINmay

Minor resultinfalsepositiveurine
opiateimmunoassayresults
duetomechanismunknown.

DIPYRONE Good NONSTEROIDAL

Minor ANTIINFLAMMATORY
AGENTSmayresultin
falselypositivefecal
hemocculttestsdueto
NSAIDinduced
gastrointestinalbleeding.

OMEPRAZOLE Excellent OMEPRAZOLEmayresult

Minor infalsenegative13Curea
breathtestresultsdueto
suppressionofHelicobacter
pylori.

DrugTABACOInteracciones(Sincoincidencias)

DrugEMBARAZOInteracciones(4)
Frmacos: Gravedad: Documentacin: Resumen:
CIPROFLOXACIN Unknown CiprofloxacinisratedasUS
FDACategoryC.Animal
studieshaveshownan
Moderate adverseeffectandthereare
noadequateandwell
controlledstudiesin
pregnantwomen.(OR)No
animalstudieshavebeen
conductedandthereareno
adequateandwellcontrolled
studiesinpregnantwomen.

DIPYRONE Unknown NoUSFDAratingis

availableforDipyrone.
Moderate

OMEPRAZOLE Unknown NoUSFDAratingis

availableforOmeprazole.
Moderate

TRAMADOLHYDROCHLORIDE Unknown TramadolisratedasUS

FDACategoryC.Animal
studieshaveshownan
Moderate adverseeffectandthereare
noadequateandwell
controlledstudiesin
pregnantwomen.(OR)No
animalstudieshavebeen
conductedandthereareno
adequateandwellcontrolled
studiesinpregnantwomen.

DrugLACTANCIAInteracciones(4)
Frmacos: Gravedad: Documentacin: Resumen:
DIPYRONE Unknown Infantriskcannotberuled
Major out:Availableevidenceand/
orexpertconsensusis
inconclusiveoris
inadequatefordetermining
infantriskwhenDipyroneis
usedduringbreastfeeding.
Weighthepotentialbenefits
oftreatmentagainst
potentialrisksbefore
prescribingDipyroneduring
breastfeeding.

OMEPRAZOLE Unknown Infantriskcannotberuled

Major out:Availableevidenceand/
orexpertconsensusis
inconclusiveoris
inadequatefordetermining
infantriskwhen
Omeprazoleisusedduring
breastfeeding.Weighthe
potentialbenefitsof

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6/11/2016 DrugInteractionsresultsMICROMEDEX
treatmentagainstpotential
risksbeforeprescribing
Omeprazoleduringbreast
feeding.

TRAMADOLHYDROCHLORIDE Unknown Infantriskcannotberuled

Major out:Availableevidenceand/
orexpertconsensusis
inconclusiveoris
inadequatefordetermining
infantriskwhenTramadolis
usedduringbreastfeeding.
Weighthepotentialbenefits
oftreatmentagainst
potentialrisksbefore
prescribingTramadolduring
breastfeeding.

CIPROFLOXACIN Unknown AccordingtotheAmerican

Minor AcademyofPediatrics,
Ciprofloxaciniscompatible
withbreastfeeding.

Definiciones
Gravedad:

Losfrmacosestncontraindicadosparasuusosimultneo
Contraindicado

Importante Lainteraccinpuedecausarlamuertey/orequeririntervencinmdica
paraminimizaroevitarefectosadversosgraves.

Moderada Lainteraccinpuedeagravarlacondicindelpaciente
y/orequerirunaalteracindelaterapia.
Lainteraccinpuedetenerefectosclnicoslimitados.Lossntomaspueden
Secundario
incluirunaumentodelafrecuenciaolagravedaddelosefectosadversos
pero,engeneral,norequerirnunaalteracinimportantedelaterapia.

Desconocida Desconocida.

Documentacin:

Excelente Losestudioscontroladoshanestablecidoclaramentelaexistenciade
interaccin.
Buena Ladocumentacinsugiereplenamentequeexisteinteraccin,
perofaltanestudiosbiencontrolados.
Suficiente Ladocumentacindisponibleesescasaperolasconsideraciones
farmacolgicashanllevadoalosmdicosasospechardelaexistenciade
interaccinoladocumentacinesbuenaparaunfrmacosimilar
farmacolgicamente.
Desconocida Desconocida.

Copyright19742016TruvenHealthAnalyticsInc.

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