Pathology Revision OSPE

Gross
2-3

Histopathology Microscopy
8 4-5

Specimen
transport / FNAC
Total stations 20
Specimen
collection
2
Haematoloy
7
3 slides

Chem. path
2 Clinical cases
3

Transfusion
2
Questions
1. This is a blood picture of a 40 yr old
female with menorrhagia
1.1 Name 4 red cell abnormalities. (6)

1.2 What is the most probable haematological

diagnosis?(2)

1.3 Name 2 serum investigations you would

request to confirm the diagnosis. (2)
 Answers
1.1 Microcytosis
Hypochromasia
Pencil cells
Anisopoikilocytosis

1.2 Iron deficiency anaemia

1.3 Serum ferritin

Serum iron
TIBC
2. This is a coagulation profile of a one
year old baby boy presented with
bruising
Test Control

PT 12 12

APTT 50 30

TT 14 14
2.1 Comment on the above investigations. (4)

2.2 Give two differential diagnoses. (3)

2.3 Name one further investigation that you

would request to come to a definite diagnosis.
(3)
 Answers
2.1 APTT prolonged
PT & TT normal

2.2 Haemophilia A / B / C
( Factor viii / ix / xi deficiency )

2.3 Factor levels

3
3.1 Identify the pathological condition. (4)

3.2 Name 3 aetiological factors for the above

condition. (6)
 Answers
3.1 Fatty liver

3.2 Alcohol
NASH ( Obesity, Type 2 DM, Dyslipidaema,
Hypertention)
4. Select the most suitable item required to
perform FNAC of thyroid nodule.
State the appropriate capital letter

1. Syringe size-
2. Needle gauge-
3. Fixative-
A

C
Q R S
X

Y
Z
 Answers

1. B
2. S
3. Y
5. Read the ABO and Rh blood group
of the three cell groupings shown.
a.
b.
c.
 Answers
a. O positive

b. A Negative

c. AB Negative
 6. This is the CSF report o a 6 months
old baby with high fever & irritability.
Appearance - slightly turbid
Protein - 5.3 g/dl
WBC - 115 cells/ mm
Polymorphs - 75%
Lymphocytes - 25 %
RBC - 2-3 cells / mm
RBS - 112 mg/dl
CSF sugar - 50 mg/dl
6.1 State 3 abnormalities of the report. (6)

6.2 What is the most probable diagnosis? (4)

 Normal Viral Pyogenic TB

Appearance Crystal clear Clear/ Turbid Turbid / Turbid /

Purulent Viscous

Mononuclear < 5/ mm 10- 100 / mm <50/ mm 100-300/ mm

cells

Polymorph Nil Nil 200 300/ 0 200 / mm

cells mm

Protein 0.2 0.4 g/dl 0.4 0.8 g/dl 0.5- 2 g/dl 0.5 3 g/dl

Glucose 2/3 blood > blood < blood < blood

glucose glucose glucose glucose
 Answers
6.1 Appearance is turbid
CSF sugar is < 1/2 of blood sugar
Polymorphs are 75%

6.2 Bacterial meningitis