Scribd Logo
Upload

Welcome to Scribd!

  • 03.aim and Objective

    Uploaded by

    C-Net Works
    8 views1 page
    The aim was to develop porous tablets of the drug loratadine using a sublimation technique involving direct compression of the drug with sublimating agents like camphor, menthol, and cross povidone as well as super disintegrants. Tablets were prepared, dried to allow sublimation of the agents and create porosity, then evaluated for properties like weight variation, hardness, drug content, and dissolution to test for rapid drug release from the porous structure.

    Original Description:

    Project on FORMULATION DEVELOPMENT AND INVITRO EVALUATION OF BOSANTAN CONTRROLLED RELEASE TABLETS

    Original Title

    03.Aim and Objective

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The aim was to develop porous tablets of the drug loratadine using a sublimation technique involving direct compression of the drug with sublimating agents like camphor, menthol, and cross povidone as well as super disintegrants. Tablets were prepared, dried to allow sublimation of the agents and create porosity, then evaluated for properties like weight variation, hardness, drug content, and dissolution to test for rapid drug release from the porous structure.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    8 views1 page

    03.aim and Objective

    Uploaded by

    C-Net Works
    The aim was to develop porous tablets of the drug loratadine using a sublimation technique involving direct compression of the drug with sublimating agents like camphor, menthol, and cross povidone as well as super disintegrants. Tablets were prepared, dried to allow sublimation of the agents and create porosity, then evaluated for properties like weight variation, hardness, drug content, and dissolution to test for rapid drug release from the porous structure.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 1

    AIM AND OBJECTIVE

    AIM AND OBJECTIVE

    The rationale of this investigation was to develop monolithic tablets of loratadine using
    sublimation technique. Porous tablets of loratadine were prepared by the direct
    compression technique using sublimating agents like camphor, menthol and cross
    povidone, CCS as super disintegrants. Sublimating agents are sublimed from the tablets
    by drying in hot air oven at 60 oC for 1hr or overnight air drying. The formulations were
    evaluated for weight variation, hardness, drug content and in vitro dissolution.

    Subliming agents increases the porosity of the tablets and ensures burst release of the
    drug.

    MRR. COLLEGE OF PHARMACY Page 24

    You might also like