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University QN Paper1990 To 2015
University QN Paper1990 To 2015
COLLECTION OF UNIVERSITY
QUESTION PAPER
1990-2015
BY
MITHRAAZ 2013 BATCH
KILPAUK MEDICAL COLLEGE
CHENNAI-10
1990-2015 MITHRAAZ13 KMC-2013
MICROBIOLOGY PAPER I
GENERAL MICROBIOLOGY
ESSAY:
1. Fluorescent Microscopy 6. Bacterial flagella (4)
7. Sterilization methods, HEPA filter, protocol 17. Dry heat sterilization (2)
to sterilize major surgical operation theatre 18. Hot air oven (4)
microbial agents and their mode of action (2) 20. Non sporing anaerobes (2)
Various disinfectant agents and their applications. 25. Sterilization by autoclave (4)
(2)
IMMUNITY
ESSAY:
10. Autoimmunity (2)
1. Methods of transmission of infection
11. Hypersensitivity reaction-type 4 and Schwartzman
2. Innate immunity reaction
3. Active and passive immunity (2) 12. Define anaphylaxis,mediators and pathogenesis
of anaphylaxis
4. Humoral immunity (2)
Development of T cells
7. Immunoglobulins (2)
6. Innate immunity (1) 37. Antigen antibody reactions and its uses in
19. Antigen presenting cells 49. Protocols for safe blood transfusion
17. Prophylaxis of diphtheria 50. Lab diagnosis leptospirosis & weils disease- lab
diagnosis (3)
18. Tests for toxin products of corynebacterium(2)
51. Standard test for syphilis
19. Eleks Test(2)
52. Lab diagnosis of secondary syphilis
20. Diptheroids
53. Leptospirosis(3)
21. Malignant pustule (5)
54. Non venereal treponemes
22. Clostridium botulinum
55. Lyme disease (2)
23. Toxins of Clostridium welchii
56. Weils disease
24. Naglers reaction (2)
57. Lab Diagnosis of mycoplasma
25. Gas Gangrene (2)
58. Nocardia
26. Tetanus prophylaxis and lab diagnosis(5)
59. Borrelia
27. Clostridium difficile
60. Gardneralla Vaginalis (2)
28. Lab Diagnosis of Anaerobic Infection
61. H.Pylori (4)
29. Bacterioids
62. Campylobacter
30. General characteristics of entero bacteriacae
63. Rickettsiae (2)
31. Diarrhoegenic E.coli (3)
64. Epidemic typhus
32. Travellers diarrhea
65. Neill Mooser (Tunica)Reaction
33. Relapsing fever(3)
66. Scrub typhus (2)
34. Lab diagnosis Enteric carriers (2)
67. Weil felix reaction (4)
35. MDR S.typhi
68. Q fever
36. Lab Diagnosis of enteric fever
69. Trench Fever
37. Vi Antigen
70. Freis Test (2)
38. Widal test (3)
71. Inclusion conjuntivitis
39. Halophilic vibrio (3)
72. TRIC agents (4)
40. Eltor Vibrio (5)
73. Guinea pig uses in microbiology
41. Prophylaxis & epidemiology of cholera
1990-2015 MITHRAAZ13 KMC-2013
74. UTI endotoxin
79. Distinguish between alpha haemolytic 12. Give two examples for transport media
streptococci and pneumococci
13. Arthus phenomenon
80.ETEC
14. Naglers reaction
81.Listeria monocytogenes
15. Cold sterilization
82.Clostridiun perfringens and toxins
16. Two uses of HLA typing
83. Non suppurative streptococcal disease
17. Oxidase test
84. Anaerobic vaginitis
18. Name the three special species of brucella
85.Melioidosis
19. Mantoux test
86.Non agglutinating vibrios
20. X and V factors
87.Legionellosis
6. Name four specific serologic tests for syphilis 12. Rhinosporidiosis / Rhinosporidium seeberi (4)
7. Four differences between exotoxin & 13. Cryptococcus Neoformens / Cryptococcosis (6)
1990-2015 MITHRAAZ13 KMC-2013
14. Sabourauds Medium 9. Viruses affecting CNS, details about rabies
15. Lab diagnosis of cryptococcal meningitis 10. Classify rhabdoviruses, details about rabies
17. Aspergilloma (2) 11. Name the virus affecting liver. Explain Hepatitis
Viruses.Details about Hepatitis B.
18. Opportunistic fungi (5)
12. Virus causing post transfusion hepatitis, detail
19. Mycotoxicosis / mycotoxins (5)
abut hepatitis B (2)
20. Cryptosporidium parvum (7)
13. Classify HHV, details about it .(1)
21. Subcutaneous mycosis
14. Classify herpes virus, detail about EBV
22. Superficial mycosis (2)
15. AIDS
23. Oppurtunistic fungal infections
16. Important Microorganism during blood
24.Chromomycosis
transmission, detail about HIV
25.Mycotic keratitis
17. Influenza virus-morphology, pathogenesis and lab
26. Tinea versicolor
diagnosis.
27. Coccidiomycosis
18. Viral vaccines
ESSAYS:
1. DNA viruses ? details about Herpes group of SHORT NOTES
viruses (2) 1. Egg culture
33. Slow viruses / slow viral disease of man and prions 2. Life cycle of plasmodium falciparum ,
(2) marphologcial differences between the
34. Viral hemorrhagic fever (5) different plasmodia
35. Rota Virus (3) 3. Parasitic zoonotic diseases, details about
36. Viral diarrhea (4) toxoplasmosis
37. Mechanism of Viral oncogenesis (2) 4. Classify cestodes, details taenia solium , lab
38. EBV (3) diagnosis of tap worm infection (3)
39. Type C hepatitis 5. Classify cestodes, details about Echinococcus
40. Lab diagnosis AIDS (2) granulosus (5
41. Methods of HIV transmission 6. Intestinal nematodes ? details about
42. Morphology and antigenic structure of HIV ankylostoma duodenale, lab diagnosis of hook
43. Eijkman test worm infection and enumerate parasites causing
44. Viral gastroenteritis(2) anaemia (3)
1990-2015 MITHRAAZ13 KMC-2013
7. Important protozoal parasites of man? Details 25. Lab diagnosis of malaria
SHORT ANSWERS :
1. Name four DNA viruses.
PATHOLOGY
2.ACUTE AND CHRONIC
1. CELLULAR ADAPTATION, CELL
INFLAMATION
INJURY, AND CELL DEATH
ESSAY:
ESSAY 1. Chemical mediators of acute inflammation
1. Necrosis , types and examples, fate of and their actions (4)
necrosed area, difference between 2. Define inflammation-Major events of acute
apoptosis and necrosis (4) inflammation and note on defective leucocytic
function.
2. Types of degeneration, pathology of
3. Vascular and cellular changes in inflammation
organ affected by fatty changes, add a
15.Apoptosis ESSAY:
16. Classify pigments. Write about lipofuscin 1. Define repair, repair of fracture of bone,
3. Wound healing second intention, difference 10. Amniotic fluid embolism (2)
between the first and second intention, factor 11. Air embolism (2)
10. Trisomy 21
SHORT NOTES:
11. Mitochondrial inheritance
1. Fat embolism (2)
12. Etiopathogenesis of cystic fibrosis
2. Edema pathogenesis
13. Hybridisation technique
3. Difference between transudate and exudates
(4)
6.DISEASES OF IMMUNITY
4. Difference between thrombus and blood clot
16. Retinoblastoma
7.NEOPLASIA
17. Hamartoma (2)
ESSAY: 18. Tumor antigens
1. Classify neoplasia, difference between benign 19. Grading and staging of tumor (2)
1. Define Gangrene , types, details about gas 3. Hemolytic diseases of newborn (5)
2. TB 5. Kwashiorkor (2)
8. Miliary TB (2)
13.RED BLOOD CELL AND BLEEDING
9. Primary Atypical pneumonia DISRODERS
10. Gangrene pathogenesis (2)
ESSAY:
11. Difference between the dry and wet gangrene
1. Classify hemolytic anemia, details about sickle
12. Leprosy
cell disease (4)
13. Mycetoma
2. Classify bleeding disorders and its lab
14. Tertiary syphilis
investigations
15. Immunology of leprosy
3. Classify hemolytic anemia, compare
16. Viral haemorrhagic fever
etiopathogenesis and lab findings of
17. Morphology of leprosy
Thalassemia and sickle cell anemia
18. Morphology of Pulmonary tuberculosis
1990-2015 MITHRAAZ13 KMC-2013
4. Classify anemia, details about iron deficiency 20. Osmotic fragility test
5. How will you interpret bone marrow, bone 22. DIC lab diagnosis (3)
17. Classify Hodgkin lymphoma (5) 15. Mention 4 indications of bone marrow
a. diagnosis
a.diagnosis
a. diagnosis
panacinar emphysema
12. THE HEART
5. Emphysema (2)
ESSAY: 6. Lobar pneumonia
1. MI (2)
4. Adamantinoma jaw
5. Paraganglioma
nephritis (2)
SHORT NOTES:
2. Chronic pyleonephritis (2)
1. Cholelithiasis (7)
3. Mechanism of glomerular injury in primary
2. Investigation of viral hepatitis (2)
glomerular diseases
3. Grey hepatitization
4. Nephritic syndrome
4. Chronic acute hepatitis (4)
12. Hepatocellular carcinoma and its etiology 6. Urinary findings of acute glomerulonephritis
1. Cervical cancer (4) 5. Phyllodes tumor breast and Mention the stromal
tumours(3)
2. Classify ovarian tumor, details about germ
6. Gynaecomastia (2)
cell ovarian tumor (2)
7. Prognostic and predictive factors of carcinoma
3. Mucinous cystadenoma of ovary breast
4. Classify ovarian tumour. Detail about serous 8. Fibroadenoma
tumour
SHORT NOTES:
24.THE ENDOCRINE SYSTEM
1. Endometriosis (3)
2. Uterus leiomyomas
ESSAY:
3. Choriocarcinoma 1.Etiopathogenesis of diabetes and complication
4. Cervical carcinoma etiopathology (4) 2. Neoplam of thyroid. Explain in detail about papillary
CA of thyroid
5. CIN (5)
15. Osteochondroma
1. Malignant melanoma (3)
16. Rhabdomycosarcoma
2. Precancerous lesion skin (2)
3. Intradermal naevus
4. Astrocytoma (4)
26.BONES, JOINTS, AND SOFT 5. Neuro fibroma
TISSUE TUMORS 6. Glioblastoma
organ.
9. A 12 yr old boy presented with fever oliguria and
highly colored urine. He had sore throat 3 weeks back.
5. 40 year old female present with post coital
a. diagnosis
bleeding, foul smelling discharge PV, she lost
b.etiopathogenesis
15 % weight in two months with loss appetite.
c. releveant investigations
Diagnosis? Etiopathogenesis & morphology of
target organ(2)
10. A 13 yr old female with massive edema ,puffiness
of face, decreased urine.
1990-2015 MITHRAAZ13 KMC-2013
a. diagnosis
b. probabale renal pathology 16. A 65 yr male patient presented with bleeding PR.
c. write in detail about minimal change disease Colonoscopy- rectosigmoid hard mass
a. Diagnosis
b. Discuss various neoplasm arising in
11. A 44 yr old nullparous women presented with
rectosigmoi and write in detail about
hard,fixed non tender mass of about 6*4*4 cms in the
morphological types and staging systems
upper outer quadrant of right breast with axillary
lymphadenopathy.
a. diagnosis
SHORT ANSWERS:
b. detail the prognostic and predictive factors of your
diagnosis 1. What are the different stages of Pneumonia?
12. A 8 yr old boy with old scars of scabies skin lesion 3. 2 differences between crohns disease &
with history of hematuria, oliguria and puffiness of
Ulcerative colitis
face.
4. Gross differences between benign and
a. diagnosis
malignant ulcers of stomach
b. etiopathogenesis and lab diagnosis
5. Enumerate 4 different types of renal stones
osteosarcoma
OTHERS:
15. Teratogenicity
16. Prodrug
3. Newer drug delivery system (2) 2. Anticholinergic drugs- uses, adverse effects
6. Post marketing surveillance during newer adverse effects and contraindication of non-
14. One anticholinergic used in eye and smooth 10. Prostaglandins & its uses (2)
muscle uses & adverse effects 11. Drug treatment migraine (3)
16. Alpha blockers- classify and uses 13. COX 2 inhibitors (2)
21. Aspirin
22. Sumatriptan
3. AUTACOIDS
23. Methotrexate
ESSAYS:
1. Analgesics (non-narcotic) Mechanism, uses
4.HORMONES
of salicylates (4)
4. Classify anti - fertility agents 25. Mech of action sulfonyl urea (2)
uses, Adverse effects . -tubocurarine its action and doses , Chlorpromazine (2)
anesthetics(2) 7. Chlorpromazine
14. Centrally acting muscle relaxant 12. Selective serotonin reuptake inhibitors (3)
Side effects of 3 groups of drugs. Diphenyl hydantoin 21. Drug therapy of Parkinsonism
Role of topiramide. Pharmoacolgy of drugs acting on 23. Rationale of ethanol in methanol poisoning
23. Venodilators
5. Verapamil
10.GIT 11.ANTIMICROBIALS
ESSAY: ESSAY:
1. Peptic ulcer drugs Classify, mechanism, 1. Antimalarial drugs classify, mechanism,
uses . Proton pump inhibitors-mechanism of action uses, adverse effects of chloroquine, Drug
and uses (2)
therapy for P. vivax (4)
2. Purgatives- mechanism, uses
2. Antiamoebic drugs. Nitroimidazole, nitazoxanid,
3. Classify dopamine receptors. Mention its agonists metronidazole- mechanism of action, spectrum of
and antagonists. Metaclopramide-mechanism of activity and uses
action, uses and adverse effects
3. Antileprotic drugs (3)
4. Discuss pharmacotherapy of H.pylori infections
4. Antituberculous treatment Classify, uses,
SHORT NOTES: Adverse effects .short course treatment of TB(4)
1. Ranitidine (3) 5. Penicillin Classify, spectrum, uses, adverse
2. Prokinetic agents (4) effect of benzyl penicillin G (3)
3. H2 blockers (3) 6. lactum antibiotic mechanism, adverse
4. Omeprazole (2) effects, uses any 3
1990-2015 MITHRAAZ13 KMC-2013
7. Antiviral drugs mechanism, action, adverse 17. Ketoconazole (4)
fungal infection. Ketaconazole action, uses and 21. Treatment of Chloroquine resistant malaria
adverse effects (2)
22. Primaquine
10. Classification of Macrolide antibiotics ,
23. Short term therapy of TB
Erythromycin
24. Multidrug therapy of TB (2)
11. Aminoglyocside antibiotics- mechanism of action,
25. Zidovudine or Azidothymidine (2)
adverse effects, therapeutic uses of gentamycin
26. Mebendazole
12. Fluroquinolones- Classification, mechanism of
action and use of second generation fluroquinolones. 27. Broad Spectrum penicillins
13. Classify antifungal drugs.Griseofulvin- action, drug 28. Drugs used in syphilis
interactions,adverse effects, therapeutic use.
29. Management of UTI
14. Cepahalosporins- action, Uses and ADR. Write
briefly about post antibiotic effect. 30. Dapsone
17. Bleomycin
anesthetics
prophylaxis of migraine.
25. Dimercaprol
the rationale.
indication.
route of administration.
indication.
1990-2015 MITHRAAZ13 KMC-2013
7. Privileged communication (2)
FORENSIC MEDICINE
8. Resipsa loquitur
1.LEGAL PROCEDURE 9. Malingering
7. Hostile witness
example
6. Infamous conduct
1990-2015 MITHRAAZ13 KMC-2013
5.DEATH AND ITS CAUSE 2. Abrasion types & medico legal importance
SHORTNOTES:
6.POSTMORTEM CHANGES
1. Difference between incised and stab wounds
ESSAY: 2. Weapon identification by examination of stab
1. Various factors that help in establishing the injuries
time since death 3. Determination of calibre of gun
2. The late changes occurring after death , 4. Abrasion collar (2)
discuss the changes taking place in 5. Laceration
decomposition and the M.L significance 6. Bomb blast injuries
3. Rigor mortis 7. Contre coupe injuries
4. Muscular changes in a Dead body (2) 8. Primary impact injuries
SHORTNOTES:
1. Postmortem caloricity 8.REGIONAL INJURIES
2. Marbling
SHORTNOTES:
3. Suspended animation
1. Skull fracture (2)
4. Infamous animation
2. Whiplash injury
5. Rigor mortis (2)
3. Scalds SHORTNOTES:
4. Joule burn
1. Hymen (3)
2. Signs of virginity
11.MECHANICAL ASPHYXIA 3. Battered baby syndrome
5. Super foetation
1. Define & Classify hanging & discuss complete
6. Signs of recent delivery in the dead
hanging (2)
7. Genital examination in rape victim
2. Classify asphyxial forms of death and
8. Section 375 of I.P.C
difference between hanging and strangulation
9. Collection of evidence in rape cases
by ligature (2)
10. Inter sex and its medico legal importance
3. Various types of violent Asphyxial Death ,
11. Sodomy (2)
Signs, symptoms, Treatment & post mortem
12. Masturbation
appearance of Drowning
13. Sexual perversions
SHORT NOTES:
14. Custodial Rape
1. Manual strangulation
15. Masochism
2. Postmortem finding in throttling
16. Medical termination of pregnancy (MTP act
3. Fracture of hyoid bone (3)
1971) (4)
4. Traumatic asphyxia (2)
17. Rules of MTP
5. Caf coronary
18. Maceration (3)
6. Postmorterm appearance of drowning (2)
19. Dead born foetus
7. Gettlers test
20. Signs of live birth
8. Diatoms test
21. Hydrostatic test (2)
9. Sexual asphyxia
22. Crib death (SIDS)
4. Obsession
SHORT NOTES:
5. Civil responsibility of insane person
1. Stupefying agents
6. Testamentary capacity insanity (2)
2. Duties of medical practitioner of the cause of
7. Mc Naughtens Rules
poisoning
8. A.L.I Test
3. Universal antidote (2)
9. Criminal responsibility of mentally ill person
4. Chronic mercury poisoning
5. Plumbism
22.ARTEFFECTS, 6. Acute lead poisoning
7. Mechanical poisons
1. Classify poisons & the duties of a doctor in a 16. Run amok (2)
case of poisoning / management of a cause 17. Difference between drug addiction and
SHORT ANSWERS:
1. Poroscopy
2. Conduct money
3. Gagging
4. Heat ruptures
5. Ricochet bullet
6. Superfoetation
7. Oxaluria
8. Viability
9. Universal antidote
10. Hippus
11. Perjury
15. Voyeurism
16. Lochia
17. Vitriolage
19. Embalming
20. Atavism