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  • Macrolide Lincosamide Tetracicline

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    Oros Codrut
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    This document summarizes the characteristics and uses of several classes of antibiotics: macrolides, lincosamides, tetracyclines. It describes their structure, spectrum of activity, toxicity, tissue diffusion, and common bacterial targets. It lists specific antibiotics within each class and indicates their common uses for treating various bacterial and parasitic infections.

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    This document summarizes the characteristics and uses of several classes of antibiotics: macrolides, lincosamides, tetracyclines. It describes their structure, spectrum of activity, toxicity, tissue diffusion, and common bacterial targets. It lists specific antibiotics within each class and indicates their common uses for treating various bacterial and parasitic infections.

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    © All Rights Reserved
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    8 views9 pages

    Macrolide Lincosamide Tetracicline

    Uploaded by

    Oros Codrut
    This document summarizes the characteristics and uses of several classes of antibiotics: macrolides, lincosamides, tetracyclines. It describes their structure, spectrum of activity, toxicity, tissue diffusion, and common bacterial targets. It lists specific antibiotics within each class and indicates their common uses for treating various bacterial and parasitic infections.

    Copyright:

    © All Rights Reserved
    Download as XLSX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as xlsx, pdf, or txt
    of 9

    Macrolide Lincosamide Tetracicline

    nucleu
    neftacencarbocami
    structura inel lactonic+glucid dic
    spectru larg larg
    toxicitate scazuta
    toleranta crescuta
    complianta buna
    difuzie tisulara buna

    bacteriostatic
    bacterii intracelulare
    tracelulare
    Eritromicina Claritromicina Azitromicina Telitromicina

    Corynebacterium difterie Mycobacterium


    sepsis erithrasma avium avium

    Chlamydia trachomatis
    (+Fluorochinolone) Chlamydia Chlamydia Chlamydia
    Strepto pneumo
    Streptococcus pneu Streptococcus pneu pyogenes

    Mycoplasma pneu Mycoplasma


    Legionella pneumophila Legionella Legionella pne
    Staphylococcus Staphy S
    Streptococcus grup A(pyogenes)

    Campylobacter jejuni Helicobacter pyloriHelicobacter pylori Helicobacter pyl


    Helicobacter pylori
    Neisseri g
    B . Fragilis
    Moraxella
    T.gondii

    Mycobacterii
    nontuberculosis
    Haemophy i.

    reducere doza in IR
    hepatita colestatica acuta hepatita,IH
    inhiba enz cit 450 inhiba CYP3A4
    ORAL,i.v. ORAL ORAL ORAL
    kanamicina ,neomicina+
    mai bine tolerata
    nu patrunde in lcr
    antiacide modif
    absorbtia
    o singura adm pe zi o singura adm pe zi
    Quinupristina/Dalfo
    Clindamicina Pristinamicina pristin Cloramfenicol
    R. la Staphy aureus bacterii
    eritromicina epidermidis (R. la anaerobe+aerobe
    Bacteroides meticilina meticilina poz +neg

    Strep
    pneumo(macrolide,pe
    anaerobi Gram poz +neg Chlamydia niciline) Rickettsiae

    Streptococcus pneu Strepto Enterococcus faecium Haemophyllua

    MRSA Clostridium perfrin Neisseria m.


    Legionella E.coli
    Staphylococcus Moraxella Moraxella osloensis
    Pneumocystis jirovecii Neisseria m Strepto pneumo

    Mycoplasma pneu

    T.gondii

    sdr.cenusiu
    inhiba CYP3A4 inhiba enzimele microsomale
    ORAL,i.v. LENT,i.m.

    nu patrunde in lcr

    Enterococcus E.faecalis Chlamydia


    Gram neg aerobi
    imele microsomale
    Tetraciclina Doxiciclina Minociclina Tigeciclina
    Rickettsii Bacteroides Enterococcus
    Mycoplasma pneumo Chlamydia Staf Staf coagulazo-neg
    Chlamydia Legionella Strepto Staf aureus
    Spirochete bacili neg aerobi Pneumo MRSA
    Helicobacter pylori Neisseria g. Moraxella Enterobacteriaecea
    Vibrio Brucella Brucella anaerobi poz neg
    Brucella Chlamydia E.coli Rickettsii
    Plasmodium falciparum Mycoplasma Hemo.i Chlmydia
    Strepto pneumo Rickettsii Klebsiella Enterococi
    Mycobacterium marinumActinomicosis Neisseria g. Acinetobscter
    Treponema palidum Vibrio Leigonella
    Borrelia micobacterii
    Chlamydia
    Mycoplasma

    oral
    Proteus
    Pseudomonas
    Coci GRAM
    NEGATIVI- Coci GRAM
    Bacili GRAM NEGATIVI- Bacili GRAM aerobi,facultati NEGATIVI-
    aerobi,facultativ anaerobi NEGATIVI-anaerobi v anaerobi anaerobi
    Enterobacteriacea Bacteroides Neisseria
    Yersinia Fusobacterium
    Citrobacter
    Enterobacillus
    Enterobacter
    Escherichia
    Klebsiella
    Proteus
    Providencia
    Salmonella
    Serratia
    Shigella
    Pseudomonas
    Vibrio
    Haemophyllus
    Legionella
    Bacili GRAM NEG- Coci GRAM Coci GRAM Bacili GRAM Bacili GRAM POZ-
    microaerofle POZ aerobi POZ-anaerobi POZ -aerobi anaerobi
    Campylobacter Staphy Peptostrepto Bacillus Actinomyces
    Helicobacter Stropto Listeria Clostridium
    Enterococcus Nocardia
    Mycopbacterium
    Lactobacillus
    Corynebacterium
    Bacterii fara
    intracelul perete
    are celular spirochete
    Chlamydia Mycoplasm Leptospira
    Rickettsia Borellia
    Coxiella Treponema

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