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Acyclovir 200 MG (Aciclovir)
Acyclovir 200 MG (Aciclovir)
A*
System Antiinfectives
Indication i)Mucocutaneous Herpes Simplex infection in immunocompromised and AIDS
patients ii)Primary and recurrent Varicella Zoster Infection in
immunocompromised and AIDS patients
iii) Severe Kaposi Varicella Eruption (Eczema herpeticum )
iv) Severe primary HSV infections ( eg. Neonatal herpes, encephalitis, eczema
herpeticum , genital herpes, gingival stomatitis, vaginal delivery with maternal vulva
herpes)
v) Severe and complicated varicella infection (eg. Encephalitis, purpura fulminans)
vi) Severe zoster infection in paediatrics ( eg.Encephalitis, purpura fulminans,
immunocompromised patients and facial, sacral and motor zoster)
Dosage i) Adult : initially 400 mg 5 times daily for 5 days. Child < 2 yrs : 200 mg 4 times daily,
Child > 2 yrs : 400 mg 4 times daily. ii), iii) and iv) Adult : 200 - 400mg 4 times daily.
Child : < 2 yrs, half adult dose; >2 yrs, adult dose.
v) Adult : 800 mg 5 times dly for 7 days vi) Adult : 20 mg/kg (max : 800 mg ) qid for 5
days , Child <2 yrs, 200 mg qid, 2-5 yrs : 400 mg qid, >6 yrs : 800 mg qid.
Contra Patients known to be hypersensitive to acyclovir.
Indication
Precautions Patients with preexisting neurologic, renal, or hepatic impairment, dehydrated patient,
elderly and lactation.
Interactions Increased mean half-life & plasma concentration with probenecid.
Adverse Skin rashes; GI effects; Fatigue.
Reactions