23/5/17 chemistry final

ROKAYA SAMI ABDULAAL / KAYA 1106

Adenosine
 Physical Properties
White to off-white crystalline powder
solid

Color :
White crystalline water [3]

Smell:
No odor[3]
Taste:
Bittersweet [3]

Melting point:
500 to 518 F - 235.5 C [3]

Solubility:
>40.1 [ug/mL] [3]

Water Solubility:
8230 mg/L [3]

Vapor Pressure:
6.0X10-15 mm Hg at 25 deg C (est) [3]

Decomposition:
When heated to decomposition, it emits toxic funes of /nitrogen oxides/.
pH [3]
pH = 4.5-7.5 (solution of 3 mg/mL adenosine and 9 mg/mL sodium
chloride in water) [3]

Dissociation Constants:
pKa1 = 3.6; pKa2 = 12.4 [3]
ChemicalProperty
[3]
 Purpose & Application

Adenosine is an antiarrhythmic and a nucleoside [1]. it treats

irregular heartbeats and slows down the electrical conduction in
the heart and normalizing the heart rhythm [4]. It improves blood
flow to the heart [4]. This drug could sometimes cause deadly
heart problems like irregular heartbeats and avoid caffeine[4].
There are also many side effects to Adenosine like Dizziness;
flushing; headache; lightheadedness; stomach pain[4]. Also it is
better to avoid adenosine if youre pregnant or trying to and if
youre breastfeeding[4]. Although Adenosine might be very useful
but it is also harmful so it better to be careful before taking it.
 Reference

Synthesis and evaluation of adenosine containing 3-arylfuran-2(5H)-ones

as tyrosyl-tRNA synthetase inhibitors. Retrieved May 22, 2017. From
http://www.sciencedirect.com/science/article/pii/S0223523417302428

Adenosine. Retrieved 22,2017. From

https://pubchem.ncbi.nlm.nih.gov/compound/adenosine#section=Top

Dipyridamole: Indications, Side Effects, Warnings. Retrieved May

22,2017. From
https://www.drugs.com/cdi/dipyridamole.html
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