(For additional information see "Ibuprofen: Drug information" and see "Ibuprofen:

Patient drug
information")
For abbreviations and symbols that may be used in Lexicomp (show table)
ALERT: US Boxed Warning
Serious cardiovascular thrombotic events (excluding NeoProfen):
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious
cardiovascular
thrombotic events, including myocardial infarction, and stroke, which can be fatal.
This risk may
occur early in treatment and may increase with duration of use.
Ibuprofen is contraindicated in the setting of coronary artery bypass graft (CABG)
surgery.
Serious gastrointestinal bleeding, ulcerations, and perforation (excluding
NeoProfen):
NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events
including
bleeding, ulceration, and perforation of the stomach or intestines, which can be
fatal. These
events can occur at any time during use and without warning symptoms. Elderly
patients and
patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater
risk for
serious GI events.
Brand Names: US Addaprin [OTC]; Advil Junior Strength [OTC]; Advil Migraine [OTC];
Advil
[OTC]; Caldolor; Childrens Advil [OTC]; Childrens Motrin Jr Strength [OTC] [DSC];
Childrens Motrin
[OTC]; Dyspel [OTC]; EnovaRX-Ibuprofen; Genpril [OTC]; GoodSense Ibuprofen
Childrens [OTC];
GoodSense Ibuprofen [OTC]; I-Prin [OTC]; IBU-200 [OTC]; Ibuprofen Comfort Pac;
Infants Advil [OTC]
KS Ibuprofen [OTC]; Motrin IB [OTC]; Motrin Infants Drops [OTC]; Motrin Junior
Strength [OTC] [DSC];
Motrin [OTC] [DSC]; NeoProfen; Provil [OTC]
Brand Names: Canada Advil; Advil Pediatric Drops; Apo-Ibuprofen; Caldolor;
Childrens
Advil; Childrens Europrofen; Ibuprofen Muscle and Joint; Jamp-Ibuprofen; Motrin;
Motrin (Children's);
Motrin IB; Novo-Profen; Pamprin Ibuprofen Formula; PMS-Ibuprofen; Super Strength
Motrin IB Liquid
Gel Capsules
Therapeutic Category Analgesic, Nonopioid; Anti-inflammatory Agent; Antipyretic;
Nonsteroidal Anti-inflammatory Drug (NSAID), Oral; Nonsteroidal Anti-inflammatory
Drug (NSAID),
Parenteral
Dosing: Neonatal
PDA closure: Note: Use birth weight to calculate all doses; monitor urine output; a
decrease in
urine output may require dose adjustment or holding of therapy.