Professional Documents
Culture Documents
Path o Physio
Path o Physio
ENDOTOXINS
OXYGEN FREE-
ACETALDEHYDE RADICALS
KUPFFER CELLS ANTIOXIDANTS
TNF-
TGF-
HEPATOCYTE INJURY
Hepatocyte injury
Stellate Cells
Increase production of ECM & Collagen
(Collagen type 1, 3 and 5)
Extensive Fibrosis
Cirrhoss