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Oxygenated and Deoxygenated Do Not Mix Due
Oxygenated and Deoxygenated Do Not Mix Due
Oxygenated and Deoxygenated Do Not Mix Due
-our report, maam just asked about molecular -oxygenated and deoxygenated do not mix due
pathway of skeletal contraction to trabeculae
1. chronotropic- bradycardia and tachycardia -non-striated unlike skeletal and cardiac bec
actin and myosin filamens not arranged into
2. inotropic sarcomere but into bundles of thick filaments in
dense bodies
3. dromotropic
-multiunitary: neurogenic meaning they rely on
-bradycardia and heart block diff neural stimulus
-heart block conduct electrical impulses Smooth muscle contraction
o Heart block -diff with skeletal, no troponin but has
caldesmon which is bound to actin, hindi
1. complete: 1st and 2nd degree
makabind actins a myosin, walang contraction,
2. incomplete: 3rd degree para magkacontraction, you have to depolarize
membrane for calcium that will bind to
o Vagal escape calmodulin (forms complex), binds to
caldesmon and removes it from actin, causing
-when sinus venosus stops, ventricle will takes contraction
its place, idioventricular rhythm enhance
heartbeat and will bring back heartbeat that o Myosin-light chain dependent
decreased to normal heart rate mechanism
-exposure of organs to adrenaline decrease rate -Smooth and Cardiac has muscarinic
(smooth especially GI tract is M3 dominant
o Vagus nerve stimulation while cardiac is M2 dominant)
-acetycholine for heart decreases heart rate due Adrenaline: Adrenergic receptor
to lowering ca levels which weaken heart
contraction -Skeletal: increase activity
-example of this is patellar reflex; part under -fastest reflex time observed at 1%HCl, proton
patella, muscle is extended there, magsstretch disprupt pH of frogs skin
and biceps femoris
-procaine is local anesthetic and inhibit
-only seen in normal frog activation of voltage sodium channels, no
depolarization will occur, no action potential
Golgi tendon reflex will drive reflex action
-when muscle contract, may reflex na mag -sodium bicarbonate and water used to stabilize
eextend siya, inhibitory response to prevent skin condition
damage
Synapses
Flexor-crossed-extensor reflex/Flexor-
withdrawal reflex -site between 2 neurons where it is close
enough to enable action potential
-response to painful stimulus
-presynaptic neuron synthesize neuro
-for example may hinawakan kang mainit na transmitters or chemical messengers to send
bagay, reflex is to stay away from it, muscles signal to next neuron, neurotransmitter travel
will contract for you to move to postsynaptic neuron
-nociceptors are pain receptors, will travel to A- -synaptic fatigue occurs when all
delta or C sensory nerve fibers (A delta is fast- neurotransmitters have travelled but
presynaptic neuron does not synthesize
neurotransmitters at same rate
Q&A