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Ganong - Physiology Self-Assessment Questions - 01
Ganong - Physiology Self-Assessment Questions - 01
Ganong - Physiology Self-Assessment Questions - 01
The primary force moving water molecules from the blood plasma to the interstitial fluid is
A. active transport
B. cotransport with H+
C. facilitated diffusion
E. filtration
Second messengers
A. Glucose-6-phosphatase
B. Adenylyl cyclase
E. Cytochrome c
E. secreted in a form that is larger than the form present in the endoplasmic reticulum
Which of the following cell membrane channels is a tetramer with a channel in each of the four
subunits?
A. CLC Cl channels
B. Aquaporins
C. Potassium channels
D. Glucose transporters
E. GABAA channels
Cell membranes
D. in some tissues permit the transport of glucose at a greater rate in the presence of
insulin
Which of the following receptors does not span the cell membrane seven times?
A. -Adrenergic receptor
B. Rhodopsin
C. 5-HTIC receptor
D. Mineralocorticoid receptor
E. LH receptor
Which of the following has both plasma membrane and intracellular receptors?
A. IL-1
B. Growth hormone
C. Ghrelin
D. Dopamine
E. Estradiol
B. Tay-Sachs disease
D. Testotoxicosis
E. Long QT syndrome
A. Cystic fibrosis
E. Hirschsprung's disease
Match the disease with the lettered item that is most closely associated with it. Many cases of
Graves' disease
B. Abnormal G protein
B. Abnormal G protein
Match the disease with the lettered item that is most closely associated with it. Some cases of
familial hypercholesterolemia
B. Abnormal G protein
Match the disease with the lettered item that is most closely associated with it. Some cases of
acromegaly
B. Abnormal G protein
Match the function with the lettered part of the cell that is most closely associated with it.
Figure 1A.
A.
B.
C.
D.
E.
Match the function with the lettered part of the cell that is most closely associated with it.
Hydrolysis of prohormones
Figure 1A.
A.
B.
C.
D.
E.
Match the function with the lettered part of the cell that is most closely associated with it.
Constitutive secretion
Figure 1A.
B.
C.
D.
E.
Match the function with the lettered part of the cell that is most closely associated with it.
Figure 1A.
Nuc, nucleus; Cell memb, cell membrane.
A.
B.
C.
D.
E.
What percentage of the human genes are involved in the formation and function of the
nervous system?
A. 5
B. 15
C. 25
D. 40
E. 60
A. A fibers
B. A fibers
C. A fibers
D. B fibers
E. C fibers
Match the function with the lettered part of the cell that is most closely associated with it.
Glycosylation of proteins
Figure 1A.
Nuc, nucleus; Cell memb, cell membrane.
A.
B.
C.
D.
E.
Deuterium oxide and inulin are injected into a normal 30-year-old man. The volume of
distribution of deuterium oxide is found to be 42 L and that of inulin 14 L.
A. The man's intracellular fluid volume is about 14 L
E. The man's total body water cannot be determined from these data
D. acting as a "relaxing protein" at rest by covering up the sites where myosin binds to
actin
Which of the following statements about nerve growth factor is not true?
C. It is necessary for the growth and development of the sympathetic nervous system
Figure 2A.
A. 15 m/s
B. 30 m/s
C. 40 m/s
D. 67.5 m/s
A. actin
B. myosin
C. troponin
D. tropomyosin
E. myelin
Which part of a neuron has the highest concentration of Na+ channels per square millimeter of
cell membrane?
A. Dendrites
C. Initial segment
A man falls into a deep sleep with one arm under his head. This arm is paralyzed when he
awakens, but it tingles, and pain sensation in it is still intact. The reason for the loss of motor
function without loss of pain sensation is that in the nerves to his arm
E. sensory nerves are nearer the bone than motor nerves and hence are less affected by
pressure
C. produces more tension when the muscle contracts isometrically than when the muscle
contracts isotonically
D. produces more work when the muscle contracts isometrically than when the muscle
contracts isotonically
C. causes the immediate uptake of Ca2+ into the lateral sacs of the sarcoplasmic reticulum
Match the statement with the lettered muscle disease that is most closely associated with it.
D. Metabolic myopathy
E. Congenital myotonia
C. are present and provide the pathway for rapid spread of excitation from one cardiac
muscle fiber to another
Match the statement with the lettered muscle disease that is most closely associated with it.
D. Metabolic myopathy
E. Congenital myotonia
Match the receptor with the one lettered statement that is most closely associated with it.
1-Adrenergic receptors
B. Blocked by Zn2+
C. Coupled to Gs
E. Inhibited by strychnine
Match the statement with the lettered muscle disease that is most closely associated with it.
D. Metabolic myopathy
E. Congenital myotonia
Match the statement with the lettered structure that is most closely associated with it.
Contain glutamate
A. Microtubules
B. Active zones
C. Nuclei
D. Clear vesicles
E. Granulated vesicles
Match the statement with the lettered structure that is most closely associated with it.
Contain acetylcholine
A. Microtubules
B. Active zones
C. Nuclei
D. Clear vesicles
E. Granulated vesicles
Match the statement with the lettered structure that is most closely associated with it.
A. Microtubules
B. Active zones
C. Nuclei
D. Clear vesicles
E. Granulated vesicles
Match the statement with the lettered structure that is most closely associated with it.
B. Active zones
C. Nuclei
D. Clear vesicles
E. Granulated vesicles
Match the receptor with the one lettered statement that is most closely associated with it.
D3 dopamine receptor
B. Blocked by Zn2+
C. Coupled to Gs
E. Inhibited by strychnine
Match the statement with the lettered structure that is most closely associated with it.
A. Microtubules
B. Active zones
C. Nuclei
D. Clear vesicles
E. Granulated vesicles
Match the receptor with the one lettered statement that is most closely associated with it.
GABAA receptor
B. Blocked by Zn2+
C. Coupled to Gs
E. Inhibited by strychnine
Match the receptor with the one lettered statement that is most closely associated with it.
NMDA receptor
B. Blocked by Zn2+
C. Coupled to Gs
A. L-Dopa
B. Dopamine
C. Norepinephrine
D. Histamine
E. Acetylcholine
Which of the following does not contain cation channels that are activated by mechanical
distortion, producing depolarization?
A. Olfactory neurons
B. Pacinian corpuscles
Which of the following receptors and sense organs are incorrectly paired?
A. Substance P
B. Met-enkephalin
C. -Endorphin
D. Serotonin
E. Dynorphin
A. Glycine receptor
B. GABAB receptor
D. 5-HT3 receptor
E. ANP receptor
C. a sensation localized to the hand when the nerves of the brachial plexus are stimulated
E. a decreased firing rate in the sensory nerve from the receptor when one's attention is
directed to another matter
Which of the following sensations is not generated by impulses initiated in naked nerve
endings?
A. Touch
B. Pain
C. Cold
D. Tickle
E. Proprioception
B. Glutamate receptors
C. GABAA receptors
D. Glucocorticoid receptors
E. 1-Adrenergic receptors
In which of the following is the frequency of stimulation not linearly related to the strength of
the sensation felt?
D. Dorsal horn
E. Cutaneous receptors
E. A complete urinalysis
Which of the following sensations is most subject to facilitation and inhibition in the central
nervous system?
A. Touch
B. Warmth
C. Pain
D. Hearing
E. Taste
A man loses his right hand in a farm accident. Four years later, he has episodes of severe pain
in the missing hand (phantom limb pain). A detailed PET scan study of his cerebral cortex
might be expected to show
A. expansion of the right hand area in his right somatic sensory area I (SI)
C. a metabolically inactive spot where his hand area in his left SI would normally be
D. projection of fibers from neighboring sensory areas into the right-hand area of his right
SI
E. projection of fibers from neighboring sensory areas into the right hand area of his left
SI
B. is a monosynaptic reflex
C. is a disynaptic reflex with a single interneuron inserted between the afferent and
efferent limbs
D. is a polysynaptic reflex with many interneurons inserted between the afferent and
efferent limbs
E. interact with other fast and slow potentials to move the membrane potential of the
postsynaptic neuron toward or away from the firing level
The distance by which two touch stimuli must be separated to be perceived as two separate
stimuli is greatest on
A. the lips
When motor neuron discharge increases at the same time as motor neuron discharge to
muscle,
D. the number of impulses in spindle Ia afferents is smaller than when discharge alone is
increased
E. the number of impulses in spindle Ia afferents is greater than when discharge alone is
increased
Figure 6A.
A, B, and C are records of action potentials in afferent nerve fibers from a muscle before and after
the muscle was stretched, as shown by the change in muscle length.
A.
B.
C.
Pain
Figure 6A.
A, B, and C are records of action potentials in afferent nerve fibers from a muscle before and after
the muscle was stretched, as shown by the change in muscle length.
A.
B.
C.
A. Morphine
B. Cholinergic antagonists
C. Adrenergic antagonists
D. Substance P antagonists
E. Anandamide
An anterolateral cordotomy is performed that produces relief of pain in the right leg. It is
effective because it interrupts the
B. Ca2+
C. NMDA receptors
D. Membrane hyperpolarization
E. Membrane depolarization
Warmth
Visceral pain
D. most closely resembles "fast pain" produced by noxious stimulation of the skin
A. 0.25 diopter
B. 0.75 diopter
C. 1.0 diopter
D. 1.33 diopters
E. 10.3 diopters
Causalgia is
A. Ciliary body
B. Iris
C. Optic disk
D. Fovea
E. Parafoveal region
Match the abnormality with the lettered disease that is most closely associated with it.
B. Myopia
C. Heteronymous hemianopia
D. Strabismus
E. Nyctalopia
Touch
A. Activation of a pathway that signals differences between S cone responses and the sum
of L and M cone responses
B. Geniculate layers 36
C. P pathway
B. cerebrospinal fluid over the parts of the brain stem that contain the vestibular nuclei
D. endolymph in the semicircular canals, with consequent bending of the cupula and
stimulation of hair cells
E. perilymph over hair cells that have their processes embedded in the tectorial
membrane
Muscle strength
Match the abnormality with the lettered disease that is most closely associated with it.
Vitamin A deficiency
B. Myopia
C. Heteronymous hemianopia
D. Strabismus
E. Nyctalopia
A. somatostatin
B. retinene1
D. scotopsin
E. aqueous humor
A. diopters
B. daltons
C. torrs
D. decibels
E. pounds
The following events that occur in rods in response to light are listed in random sequence:
1. Activation of transducin;
A. 2, 1, 3, 5, 4
B. 1, 2, 3, 5, 4
C. 5, 3, 1, 4, 2
D. 3, 1, 5, 4, 2
E. 3, 1, 4, 5, 2
Abnormal color vision is 20 times more common in men than women because most cases are
caused by an abnormal
E. generally larger in musicians with perfect pitch than in musicians without perfect pitch
Question 94 of 576 < Previous question Next question >
Structure V
Figure 9A.
Human ear.
Match the abnormality with the lettered disease that is most closely associated with it.
B. Myopia
C. Heteronymous hemianopia
D. Strabismus
E. Nyctalopia
A patient enters the hospital for evaluation of deafness. He is found to also have an elevated
plasma renin, although his blood pressure is 118/75 mm Hg. Mutation of what single gene
would be likely to explain these findings?
Match the abnormality with the lettered disease that is most closely associated with it.
B. Myopia
C. Heteronymous hemianopia
D. Strabismus
E. Nyctalopia
A. limbic system
D. postcentral gyrus
E. pain receptors
Deficiency of which of the following substances causes the combination of diminished sense of
smell and hypogonadism?
A. Folic acid
B. A transcription factor
C. An adhesion molecule
D. GnRH
C. May involve either somatic or visceral responses but never both simultaneously
Structure X
Figure 9A.
Human ear.
C. vibrates in a pattern determined by the form of the traveling wave in the fluids in the
cochlea
D. is under tension
A. VIP receptor
B. Norepinephrine receptor
C. GABAA receptor
D. GABAB receptor
Structure W
Figure 9A.
Human ear.
Match the item with the lettered structure that is most closely associated with it.
Umami taste
C. Toxic substances
E. Monosodium glutamate
D. pass to the mitral cells and from there directly to the olfactory cortex
E. pass to the mitral cells and from there to the olfactory cortex via the taste area
A. formation of perilymph
D. perception of sound
Figure 6A.
A, B, and C are records of action potentials in afferent nerve fibers from a muscle before and after
the muscle was stretched, as shown by the change in muscle length.
A.
B.
C.
Match the item with the lettered structure that is most closely associated with it.
Bitter taste
E. Monosodium glutamate
Structure Z
Figure 9A.
Human ear.
Structure Y
Figure 9A.
Human ear.
Impulses generated in the taste buds of the tongue reach the cerebral cortex via the
A. thalamus
B. internal capsule
C. dorsal roots of the first cervical spinal nerves
D. trochlear nerve
E. hypoglossal nerve
Match the item with the lettered structure that is most closely associated with it.
Sexual identity
C. Toxic substances
E. Monosodium glutamate
Dreaming
Which of the following does not increase the ability to discriminate many different odors?
A. Many different receptors
E. Sniffing
A localized lesion in which of the following structures would be expected to produce prolonged
coma?
B. Locus ceruleus
A. skeletal muscles
B. medulla oblongata
C. hypothalamus
D. olfactory bulb
E. neocortex
In a healthy, alert adult sitting with the eyes closed, the dominant EEG rhythm observed with
electrodes over the occipital lobes is
Match the item with the lettered structure that is most closely associated with it.
Pheromones