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    This document outlines the general mechanisms of pain transmission in the human body. Pain signals are generated by damage to tissues which release chemical mediators that stimulate polymodal and thermal nociceptors. These nociceptors transmit neural signals via either small myelinated A-delta fibers, resulting in sharp, fast pain, or unmyelinated C-fibers, producing slow, dull pain. Mechanical stimulants can also directly activate mechanical nociceptors.

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    This document outlines the general mechanisms of pain transmission in the human body. Pain signals are generated by damage to tissues which release chemical mediators that stimulate polymodal and thermal nociceptors. These nociceptors transmit neural signals via either small myelinated A-delta fibers, resulting in sharp, fast pain, or unmyelinated C-fibers, producing slow, dull pain. Mechanical stimulants can also directly activate mechanical nociceptors.

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    10 views1 page

    JHBJ Qwjbqi Iqjegb

    Uploaded by

    Bob
    This document outlines the general mechanisms of pain transmission in the human body. Pain signals are generated by damage to tissues which release chemical mediators that stimulate polymodal and thermal nociceptors. These nociceptors transmit neural signals via either small myelinated A-delta fibers, resulting in sharp, fast pain, or unmyelinated C-fibers, producing slow, dull pain. Mechanical stimulants can also directly activate mechanical nociceptors.

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    General Mechanisms of Pain

    Neural signals
    Stimulate Slow, poorly
    Any form of damage Release of chemical carried by
    Chemical stimulants polymodal localised, dull/
    to tissues mediators unmyelinated C-
    nociceptors burning pain
    fibres

    Stimulate
    Mechanical
    mechanical
    stimulants
    nociceptors
    Nervous signals
    carried by small, Sharp easily
    myelinated A-delta localised fast pain
    fibres

    Temperature Stimulate thermal


    stimulants nociceptors

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