Atorvastatin

(Drug Use Evaluation, DUE)

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-. HN...
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Simvastatin 40 mg/day 6 LDL-C

CHD CHD risk equivalent LDL 130 mg/dl ( LDL < 100 mg/dl)
Atherosclerotic cardiovascular disease (ASCVD)
LDL-C 190 mg/dl
40-75 LDL-C 70-189 mg/dl
Simvastatin
Rhabdomyolysis
CK 5-10
AST, ALT (AST 5-35, ALT 8-40 U/L)
CPK ( 25-284 , 25 -150 U/L)
Drug interaction Simvastatin
Itraconazole Ketoconazole Erythromycin
Clarithromycin HIV protease inhibitors Gemfibrozil
().
Simvastatin ................................................................................................................
..

Simvastatin 10 mg 20 mg 40 mg ...
Atorvastatin 10 mg 20 mg 40 mg 80 mg

TC. mg/dl TG. mg/dl LDL = TC - HDL - (TG/5)

HDL-C...mg/dl LDL-C.mg/dl
/ staff
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