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Ψυχοδραστικες Ουσιες Αλεβιζοπουλος Χατζουλης2013 PDF
Ψυχοδραστικες Ουσιες Αλεβιζοπουλος Χατζουλης2013 PDF
Ψυχοδραστικες Ουσιες Αλεβιζοπουλος Χατζουλης2013 PDF
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19 (51%)
1984-2011 ( 15-19 )
1984 1998
2003
2011
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50-60%
(Kendler 1999)
40% (Tsuang
et al 1996), (Kendler et al 1999) 60-
70%
Addictions Array HPA & Adrenergic
130 Genes
Tagged with Stress Other Metabolic Serotonin
ADRA1A BDNF ALDH1A
1350 SNPs CRH ADRA2A CCK ALDH2 HTR1A
CRHBP CAT HTR1B
CRHR1
ADRA2B
ADRA2C
CCKAR
CYP2E1 Dopamine HTR2A
CCKBR
CRHR2 ADRB2 ADH1A HTR2C
CLOCK DDC
GAL ARRB2 ADH1B HTR3A
HCRT DRD1
NPY SLC6A2 ADH1C HTR3B
OXT DRD2
NPY1R DBH ADH4 MAOA
NR3C1 DRD3
NPY2R MAOB
Signal NPY5R
SLC29A1 ADH5
ADH6
DRD4
SLC6A3
TAC1 DRD5
Transduction CART ADH7 SLC18A2 SLC6A4
TPH2
TH
ADCY7
AVPR1A Cholinergic COMT
AVPR1B
CDK5R1 CHRM1
CREB1 CHRM2 GABA
CSNK1E CHRM3
FEV CHRM4 GABRA2
FOS CHRM5 GABRA4
FOSL1 CHRNA4 GABRA6
FOSL2 CHRNB2 GABRB1
GSK3B GABRB2
JUN GABRB3
MAPK1 GABRD
MAPK3 GABRG2
MPDZ Opioid GABRG3
NGFB OPRM1 SLC6A11
NTRK2
NTSR1
NMDA Glycine OPRD1 SLCSA13
GAD1
OPRK1
NTSR2 Cannabinoid GRIK1 OPRL1 GAD2
PPP1R1 GRIN1 GLRA1 PDYN VIAAT
BPRKCE GRIN2A GLRA2 PENK DBI
CNR1 GRIN2B
FAAH GLRB PNOC
GRM1 GPHN POMC
: D. Goldman, NIH
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