DRUG INDEX

ABELA, LORENZO 57M

DRUG CLASS DOSE
Febuxostat
Furosemide Sulfonamide diuretics Adult: 40-80 mg daily, alone or in
conjunction with other
antihypertensives.
Oral Oedema associated with
heart failure Adult: Initially, 20 mg
daily or 40 mg every other day for
mild cases, or 40 mg once daily
adjusted according to response. In
some cases, 80 mg or more daily as
a single dose or in 2 divided doses
may be required. Max: 600 mg daily
in severe cases.
MECHANISM OF ACTION WOF/ADR
selectively inhibits xanthine
oxidase; thereby decreasing
serum concentrations of uric
acid.
Furosemide inhibits reabsorption of Fluid and electrolyte imbalance.
Na and chloride mainly in the Rashes, photosensitivity, nausea,
medullary portion of the ascending diarrhoea, blurred vision, dizziness,
Loop of Henle. Excretion of headache, hypotension. Bone
potassium and ammonia is also marrow depression (rare), hepatic
increased while uric acid excretion is dysfunction. Hyperglycaemia,
reduced. It increases plasma-renin glycosuria, ototoxicity.
levels and secondary
hyperaldosteronism may result.
Furosemide reduces BP in
hypertensives as well as in
normotensives. It also reduces
pulmonary oedema before diuresis
has set in.

Ketoanalogue
Sodium Bicarbonate
Pioglitazone
Glimeperide
Linagliptin
Rosuvastatin competitively inhibits HMG-CoA
reductase, the enzyme This
results in the induction of the
LDL receptors and stimulation
of LDL catabolism, leading to
lowered LDL-cholesterol
levels.that catalyses the
conversion of HMG-CoA to
mevalonate.

Felodipine
Nebivolol
Clonidine
Alprazolam Alprazolam has anxiolytic,
muscle-relaxant,
anticonvulsant, antidepressant
and sleep-modifying effects. It
binds to the aminobutyric
acid (GABA)-specific sites
throughout the CNS, leading
to an increase in the inhibitory
effect of GABA on neuronal
excitability. Increased
neuronal permeability to
chloride ions thus results in
hyperpolarisation and
stabilisation.