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Psychiatry Journal
Volume 2014, Article ID 694565, 7 pages
http://dx.doi.org/10.1155/2014/694565
Research Article
Perceived Stigma and Associated Factors among People with
Schizophrenia at Amanuel Mental Specialized Hospital, Addis
Ababa, Ethiopia: A Cross-Sectional Institution Based Study
Received 18 February 2014; Revised 23 April 2014; Accepted 7 May 2014; Published 21 May 2014
Copyright 2014 B. B. Bifftu and B. A. Dachew. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background. While effective treatments are available for people with schizophrenia, presence of perceived stigma prevents them
from accessing and receiving the help they need to get. Objectives. To assess the prevalence and associated factors of perceived stigma
among people with schizophrenia attending the Outpatient Department of Amanuel Mental Specialized Hospital, Addis Ababa,
Ethiopia. Methods. Institution based cross-sectional study design was conducted among 411 subjects using an Amharic version
of the perceived devaluation and discrimination scale. Single population proportion formula was used to calculate sample size.
Subjects were selected by systematic sampling techniques. Binary logistic regression and odds ratio with 95% confidence interval
were used to identify the association factors of outcome variables. Results. A total of 411 subjects participated in the study giving
a response rate of 97.4%. The prevalence of perceived stigma was found to be 83.5%. Education status (not able to read and write)
(AOR = 2.64, 95% CI: 1.118, 6.227), difficulties of adherence to antipsychotic drug (AOR = 4.49, 95% CI: 2.309, 8.732), and duration
of illness less than one year (AOR = 3.48, 95% CI: 2.238, 5.422) were factors associated with perceived stigma. Conclusion. Overall,
the prevalence of perceived stigma was found to be high. Education status (not able to read and write), difficulties of adherence
to antipsychotic medication, and duration of illness were factors associated with perceived stigma. Adherence to antipsychotic
medication particularly during the early stage of the illness and strengthening the educational status of the participants were
suggested in the clinical care setting.
score (this criterion represented the midpoint on the 14- Table 1: Sociodemographic characteristics of participants ( = 411)
item scale) on PDD scales. Then perceived stigma scores were at Amanuel Mental Specialized Hospital, 2012.
dichotomized as those participants scoring greater than or
Characteristics Number Percent
equal to the mean score of 2.5 on PDD scales as having high
perceived stigma and those scoring below the mean score as Sex
having low perceived stigma. Male 302 73.5
Furthermore, we asked two questions on antipsychotic Female 109 26.5
medication adherence and difficulties of patients adherence Age
to their clinic appointments (follow-up). The antipsychotic 1824 84 20.4
medication adherence question asked about history of non- 2534 162 39.4
adherence with antipsychotic medications and whether the 3544 114 27.7
nonadherence behavior was linked to stigma with yes/no 44 51 12.4
response. Specifically, we asked, have you ever discontinued Educational status
your antipsychotic medication because of fear of perceived
Cannot read and write 40 9.5
stigma associated with your mental illness? Have you ever
discontinued your clinic appointments (follow-up) because Primary 289 70.3
of fear of perceived stigma associated with your mental Secondary and above 52 20
illness? Religion
Muslim 91 22.1
2.5. Data Collection and Analysis. Data were collected by Orthodox 240 58.4
face-to-face interview using a semistructured questionnaire Protestant 67 16.3
with the Amharic version of the sociodemographic, clinical Catholic 13 3.2
factors, and perceived devaluation and discrimination ques- Marital status
tionnaires. Married 72 17.5
Data were coded and entered into EPI info version Single 286 69.6
3.5.3 statistical software and then exported to SPSS windows Divorced/widowed 53 12.8
version 16 program for analysis. Descriptive statistics (fre- Ethnicity
quencies, tables, percentages, means, and standard deviation)
Oromo 132 32.1
were used for the sociodemographic and clinical variables
Amhara 146 35.6
including individuals response items to PDD. Binary logistic
regression and odds ratio with 95% confidence interval were Gurage 98 23.8
used to identify the associated factors of outcome variable. Tigre 35 8.5
A significance level of 0.05 was taken as cut-off value for all Employment
statistical significance tests. Unemployed 257 62.5
Employed 154 37.5
2.6. Ethical Consideration. The study proposal was initially Residence
approved by the ethical review board of The University of Rural 89 21.7
Gondar and Amanuel Mental Specialized Hospital. A formal Urban 322 78.3
letter of permission was obtained from the hospital and Living arrangement
submitted to the respective Outpatient Department. The Family 360 87.6
information about the study was given to the participants. Alone 51 12.4
Verbal then written informed consent was sought for each
participant who agreed to participate in the study and fulfilled
the inclusions criteria. Only anonymous data were collected
in private rooms. marital status. One hundred and six (35.5%) of the partici-
pants were Amhara in Ethnicity. Out of 411 participants, 257
(62.5%) were unemployed, 322 (78.3%) were living in urban
3. Results areas, and 360 (87.6%) were living with their family (Table 1).
A total of 411 participants participated in this study with a
97.4% response rate. One of the participants failed to complete 3.2. Clinical Characteristics. Regarding the clinical character-
the interview because of the illness and nine questions were istics of participants, 117 (28.5%) were treated for 25 years,
not fulfilled properly. 287 (69.8%) had difficulties of attending clinic (follow-up),
and 64 (15.6%) had difficulties of adherence to antipsychotic
3.1. Sociodemographic Characteristics. The majority of the medication (Table 2).
participants were males 302 (73.5%). The mean ages of the
participants were 33.249.73 years. Two hundred and eighty- 3.3. Prevalence of Perceived Stigma. Overall, the prevalence of
nine (70.3%) of the participants were primary educated, 240 perceived stigma was found to be 83.5%. Regarding the pro-
(58.4%) were Orthodox, and 286 (69.6%) were single in portion of perceived stigma toward each item, the majority
4 Psychiatry Journal
Table 2: Distribution of participants ( = 411) by clinical studies from 1994 to 2011 also reported on average 64.5% of
characteristics at Amanuel Mental Specialized Hospital, 2012. participants perceived stigma [23].
This variation may be due to shared social percep-
Characteristics Frequency Percent
tion toward mental illness. A previous study relatives of
Duration of the treatment (in years) schizophrenia and affective disorder revealed that 75% of
1 101 24.5 respondents had perceived stigma in Ethiopia and since the
25 117 28.5 study subjects were drawn from these societies, they may
610 90 21.9 share the societys perception about mental illness stigma
[20]. This relationship indicates or supports the evidence of
11 103 25.1
relation between public stigma toward mental illness and
Duration of illness (in years) perceived stigma. This variation could be also due to the
1 204 49.6 differences in sample size, the population surveyed in the
25 78 19 setting, method of data collection, and lack of antistigma
610 45 10.9 interventions program in the study area.
11 84 20.5 Even if the ways in which the respondents experience
Follow-up adherence to clinic of perceived stigma toward each item was different from
appointment the study done in Ghana using the same tool because of
287 69.8
differences in the culture, setting, and other factors, there are
Yes
also a number of similarities reported. For example, 85.7%
No 124 30.2
of Ghanaian participants agreed with the item opinions of
Difficulty of adherence to antipsychotic a mentally ill person were taken less seriously compared to
drug 81% in this study and 77.2% of the participants agreed with
Yes 64 15.6 the item most employers would pass over an application
No 347 84.4 of a former mental patient in favour of another applicant
compared to 76.1% in this study [19].
Regarding the associated factors, those patients who
cannot read and write were more than two times (AOR =
(362) (88.07%) of the participants agreed with the item most 2.64, 95% CI: 1.118, 6.227) more likely to develop perceived
people think that a person who has been hospitalized for stigma than those patients who had educational status of
mental illness is dangerous and unpredictable (Table 3). secondary level and above. These results were consistent with
the previous study [12, 2426]. This is due to the fact that
3.4. Factors Associated with Perceived Stigma. From the bivar- those patients who cannot read and write may have poor
iate analysis, educational statuses, employment, residence, coping strategies to perceived stigma.
duration of illness, and difficulties of adherence to antipsy- From clinical variables those patients who had difficulties
chotic medication were factors associated with perceived of adherence to their antipsychotic medication were more
stigma in bivariate analyses and entered into multivariate than four times (AOR = 4.49, 95% CI: 2.309, 8.732) more
analysis. likely to experience perceived stigma than those patients who
On the other hand, age, sex, ethnicity, marital status, adhere to their medication. These results were consistent
religion, difficulties of adherence to clinic (follow-up), and with the meta-analysis carried out among one hundred and
living arrangement were not associated and were excluded twenty-seven studies in Europe [15, 27, 28]. This may be
from further analysis. due to fear of stigma and rejection which could prolong
From the multivariate analysis, education status (not the duration of help seeking and reduce the likelihood
able to read and write) (AOR = 2.64, 95% CI: 1.118, 6.227), of adherence to treatment. This may in turn result in an
difficulties of adherence to antipsychotic medication (AOR = increased risk of socially unacceptable violent behavior which
4.49, 95% CI: 2.309, 8.732), and duration of illness 1 year creates stigma.
(AOR = 3.48, 95% CI: 2.238, 5.422) were factors statistically Those patients who had less than or equal to one year
significant with perceived stigma (Table 4). duration of illness had more than three times (AOR = 3.48,
95% CI: 2.238, 5.422) perceived stigma than those patients
who had greater than one year duration of their illness.
4. Discussion These results were consistent with the previous studies in
India and Europe [22, 23, 29]. This may be due to the
The aim of this study was to assess the prevalence of presence of socially unacceptable behavior seen predom-
perceived stigma and associated factors among people with inantly during the acute phase of the illness. Behaviours
schizophrenia at Amanuel Mental Specialized Hospital. This such as hallucinations, delusions, and suspicion were found
study shows that overall the prevalence of perceived stigma to be very distressing and associated with the creation of
was found to be 83.5%. This study was higher when compared stigma. Another possible reason may be that since perceived
with the cross-sectional study carried out across 14 European stigma was the result of perception of public stigma, through
countries using the same tool. That study reported 69.4% [22] time, the patient may develop stigma resistance through
and a systematic review of studies including 54 published experience.
Psychiatry Journal 5
Table 3: Proportion of perceived stigma response of participants ( = 411) to each item at Amanuel Mental Specialized Hospital, 2012.
1 Most people would be close friends with a person who once had 22 267 116 6
severe mental illness.
2 Most people believe that a person who has severe mental illness is just 23 280 106 2
as intelligent as anyone else.
3 Most people believe that a person who has been treated for severe 12 246 151 2
mental illness is just as trustworthy as anyone else.
4 Most people would accept a person who has had severe mental illness 24 297 81 9
as a teacher in a school.
5 Most people believe that receiving treatment for severe mental illness 3 101 291 16
is a sign of personal failure.
Most people will not hire a person who has been hospitalized for
6 severe mental illness to take care of their children, even if he or she 3 174 214 20
had been well for some time.
7 Most people think less of a person who has been treated for severe 16 62 288 45
mental illness.
8 Most employers will hire a qualified person even if he or she has been 18 161 227 5
treated for severe mental illness.
9 Most employers would prefer to hire someone who does not have a 5 93 298 15
history of severe mental illness.
10 Most people I know would treat a person who has been treated for 9 157 239 6
severe mental illness the same way they treat everyone else.
11 Most young women would be reluctant to date a man who has been 37 358 12 4
treated for severe mental illness.
12 Most people think that a person who has been hospitalized for severe 3 46 346 16
mental illness is dangerous and unpredictable.
Table 4: Factors associated with perceived stigma (bivariate and multivariate) analysis, at Amanuel Mental Specialized Hospital, 2012.
Perceived stigma
Explanatory variables COR (95% CI) AOR (95% CI)
High Low
Education
Not able to read and write 27 13 2.93 (1.325, 6.488) 2.64 (1.118, 6.227)
Primary 143 146 1.38 (0.842, 2.271)
Secondary and above 34 48 1 1
Employment
Unemployed 135 122 1.36 (1.213, 4.036)
Employed 69 85 1
Residence
Rural 51 38 1.48 (1.323, 5.38)
Urban 153 169 1 1
Difficulty of adherence to antipsychotic medication
Yes 43 21 2.37 (1.347, 4.153) 4.49 (2.309, 8.732)
No 161 186 1 1
Duration of illness
>1 year 81 126 1 1
1 year 131 73 2.79 (1.872, 4.164) 3.48 (2.238, 5.422)
Note: not statistically significant using forward stepwise regression methods. Hosmer and Lemeshow test was 0.191.
4.1. Strength of the Study. This study is the first of its kind of the findings. Recall and response biases might have
in Ethiopia to show perceived stigma among people with occurred when completing the questionnaire. In addition,
schizophrenia using a standard tool. some of the independent variables were assessed with
single questions, for example, treatment adherence and
4.2. Limitations of the Study. The lack of published lit- difficulties of follow-up adherence to their clinic appoin-
erature in Ethiopia limits the comparison (discussion) tments.
6 Psychiatry Journal
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Psychiatry Journal 7
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