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    Review3 03

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    AyioKun
    This document provides an overview of different classes of viruses: 1) Retroviruses like HIV and HTLV contain the enzyme reverse transcriptase and integrate their genetic material into the host cell genome. They have complex life cycles and can cause diseases like AIDS. 2) Parvoviruses and polyomaviruses are small DNA viruses with few genes. Parvoviruses cause diseases like fifth disease while polyomaviruses can cause cancers. 3) Herpesviruses are enveloped DNA viruses like herpes simplex that can cause latent and recurrent infections as well as several cancers in humans.

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    Review3 03

    Uploaded by

    AyioKun
    20 views1 page
    This document provides an overview of different classes of viruses: 1) Retroviruses like HIV and HTLV contain the enzyme reverse transcriptase and integrate their genetic material into the host cell genome. They have complex life cycles and can cause diseases like AIDS. 2) Parvoviruses and polyomaviruses are small DNA viruses with few genes. Parvoviruses cause diseases like fifth disease while polyomaviruses can cause cancers. 3) Herpesviruses are enveloped DNA viruses like herpes simplex that can cause latent and recurrent infections as well as several cancers in humans.

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    Review3.03

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    This document provides an overview of different classes of viruses: 1) Retroviruses like HIV and HTLV contain the enzyme reverse transcriptase and integrate their genetic material into the host cell genome. They have complex life cycles and can cause diseases like AIDS. 2) Parvoviruses and polyomaviruses are small DNA viruses with few genes. Parvoviruses cause diseases like fifth disease while polyomaviruses can cause cancers. 3) Herpesviruses are enveloped DNA viruses like herpes simplex that can cause latent and recurrent infections as well as several cancers in humans.

    Copyright:

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    Download as PDF, TXT or read online from Scribd
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    20 views1 page

    Review3 03

    Uploaded by

    AyioKun
    This document provides an overview of different classes of viruses: 1) Retroviruses like HIV and HTLV contain the enzyme reverse transcriptase and integrate their genetic material into the host cell genome. They have complex life cycles and can cause diseases like AIDS. 2) Parvoviruses and polyomaviruses are small DNA viruses with few genes. Parvoviruses cause diseases like fifth disease while polyomaviruses can cause cancers. 3) Herpesviruses are enveloped DNA viruses like herpes simplex that can cause latent and recurrent infections as well as several cancers in humans.

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    of 1

    CLASS REVIEW SESSION III

    I. VIRUSES WITH REVERSE TRANSCRIPTASES


    RETROVIRIDAE
    EIGHT GENERA: ONCORNAVIRUS, LENTIVIRUS HIV-1, SIVs
    FOUR ENZYMES: RT, RNAseH, INT & PRO RSV, MMTV
    LTR-gag-pol-env-LTR HTLV-1
    UNUSUAL LIFE CYCLE WITH INTEGRATION many others
    POLYPROTEINS & PROGRAMMED FRAMESHIFTING
    DISCOVERY OF V-ONCs, AIDS
    HEPADNAVIRIDAE HBV
    PARTIALLY DS DNA CIRCLE
    RT MAKES >FULL-LENGTH mRNA
    FOUR PROMOTERS - FOUR PROTEINS
    II. THE NON-ENVELOPED, DNA VIRUSES
    PARVOVIRIDAE
    ONLY SS DNA VIRUS FAMILY
    TWO GENES - REPLICASE & CAPSID AAV1-6,
    SELF-PRIMED DNA SYNTHESIS, NICKASE B19, CPV
    FIFTH'S DISEASE
    POLYOMAVIRIDAE SV-40, JC,BK
    EARLY & LATE TRANSCRIPTION: T & VP MOUSE POLYOMA
    CCC DNA, CIRC BIDIRECT REPLICATION
    VIRAL ONCOGENES (BINDING p53 & Rb)
    PML AND JC VIRUS
    PAPILLOMAVIRIDAE WART VIRUSES
    E AND L GENES 82 HPVs
    TWO OR THREE PROMOTERS, SPLICING HPV-16 & -18
    E5, E6 & E7 ARE ONCOGENES
    HUMAN CANCERS
    ADENOVIRIDAE HAdV1-HAdV51
    EARLY (E1-E4) & LATE (VIRION) GENES
    LATE GENE SPLICING, PROTEIN PRIMER
    ARD AND OTHER RESPIRATORY DISEASES
    III. THE ENVELOPED, DNA VIRUSES
    HERPESVIRIDAE
    ICOSAHEDRAL (T=16) CAPSID, COMPLEX DNA 8 HUMAN VIRUSES:
    THREE CLASSES OF mRNA, PROTEINS HERPES SIMPLEX
    LATENT-RECURRENT INFECTIONS VZV, EBV, CMV
    SEVERAL HUMAN CANCERS
    POXVIRIDAE
    COMPLEX VIRUS, CLOSED DNA VARIOLA, MCV
    MININUCLEUS, MANY ENZYMES
    SMALLPOX & ITS ERADICATION
    IV. SATELLITE RNAs AND SATELLITE VIRUSES
    PLANT VIRUSES WITH HELPER TMVS, PMVS
    OTHERS: P2-P4, AAVs, HDV
    RNAs PACKAGED WITH PLANT VIRUSES CARNA5,VIRUSOIDS
    V. VIROIDS AND PRIONS
    VIROIDS ARE PLANT PATHOGENS PSTVd, CCCVd
    SMALL RNAs, REP BY RNAPII
    c
    PRIONS - INFECTIOUS PROTEIN PRNP & PrP
    MAMMALIAN GENE & ITS PROTEIN
    FATAL NEUROLOGICAL DISEASES: CJD, KURU

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