Pediatric

drugs info
Acetaminophen Elixir(oral solution) 120mg=5cc drop:100mg/ml

10-15 mg/kg/dose 10kg=5cc qid

drop;2.5drop/kg

Pain or fever: Oral, rectal Children <12 years: 10-15 mg/kg/dose every 4-6
hours as needed; do not exceed 5 doses (2.6 g) in 24 hours
Limit dose to <4 g/day

Activated charcoal Antidiarrheal

Antidote, Adsorbent

Antiflatulent

5-10 [intoxicated drug] 30-100mg/250cc water

Single dose: Charcoal in water (a cathartic such as sorbitol should be added

in appropriate doses):

Infants <1 year: 1 g/kg

Children 1-12 years: 1-2 g/kg or 25-50 g

Adolescents and Adults: 30-100 g or 1-2 g/kg

Adult cold Acetaminophen 325+Phenylephrine HCL 5mg+Chlorpheniramine 2mg

Amoxiciline susp 125 & 250=5cc cap 250 & 500 mg

20-40 mg/kg/24hrs

10 kg =5cc tds

DOSING: PEDIATRIC

Susceptible infections: Oral:

Children 3 months: 20-30 mg/kg/day divided every 12 hours

Children: >3 months and <40 kg: Dosing range: 20-50 mg/kg/day in divided doses every 8-12 hours

Ear, nose, throat, genitourinary tract, or skin/skin structure infections: Oral: Children: >3 months and
<40 kg:

Mild-to-moderate: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every
8 hours

Severe: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Acute otitis media: Oral: Children: >3 months and <40 kg: 80-90 mg/kg/day divided every 12 hours

Lower respiratory tract infections: Oral: Children: >3 months and <40 kg: 45 mg/kg/day in divided doses
every 12 hours or 40 mg/kg/day in divided doses every 8 hours

Subacute bacterial endocarditis prophylaxis: Oral: Children: >3 months and <40 kg: 50 mg/kg 1 hour
before procedure

Anthrax exposure (unlabeled use): Oral: Note: Postexposure prophylaxis only with documented
susceptible organisms:

<40 kg: 15 mg/kg every 8 hours

40 kg: 500 mg every 8 hours

Co-amoxyclav tab 375mg Susp 312mg : 250mg Amoxy/5cc

tds
Ampiciline susp 125 & 250=5cc cap 250 & 500 mg

50-100 mg/kg/24 hrs 10kg=5cc qid

DOSING: PEDIATRIC

Mild-to-moderate infections: Infants and Children:

I.M., I.V.: 100-150 mg/kg/day in divided doses every 6 hours (maximum: 2-4 g/day)

Oral: 50-100 mg/kg/day in doses divided every 6 hours (maximum: 2-4 g/day)

Severe infections/meningitis: Infants and Children: I.M., I.V.: 200-400 mg/kg/day in divided doses every
6 hours (maximum: 6-12 g/day)

Endocarditis prophylaxis: Infants and Children: I.M., I.V.:

Dental, oral, respiratory tract, or esophageal procedures: 50 mg/kg within 30 minutes prior to procedure
in patients unable to take oral amoxicillin

Genitourinary and gastrointestinal tract (except esophageal) procedures:

High-risk patients: 50 mg/kg (maximum: 2 g) within 30 minutes prior to procedure, followed by

ampicillin 25 mg/kg (or amoxicillin 25 mg/kg orally) 6 hours later; must be used in combination with
gentamicin.

Moderate-risk patients: 50 mg/kg within 30 minutes prior to procedure.

AL-MG-S AL(OH)3 225mg/5cc syr 1-2 cc/kg/24hrs

MG(OH)2 200mg/5cc

Simethicone(Gas-X) 25mg/5cc

Atrovent(ipratropium bromide)

DOSING: PEDIATRIC

Bronchospasm:

Nebulization:

Infants and Children 12 years: 125-250 mcg 3 times/day

Children >12 years: Refer to adult dosing.

Metered dose inhaler:

Children 3-12 years: 1-2 inhalations 3 times/day, up to 6 inhalations/24 hours

 Children >12 years: Refer to adult dosing.

Colds (symptomatic relief of rhinorrhea): Intranasal: Safety and efficacy of use beyond 4 days in patients
with the common cold have not been established:

Children 5-11 years: 0.06%: 2 sprays in each nostril 3 times/day

Children 5 years and Adults: 0.06%: 2 sprays in each nostril 3-4 times/day

Allergic/nonallergic rhinitis: Intranasal: Children 6 years: Refer to adult dosing.

USE Anticholinergic bronchodilator used in bronchospasm associated with COPD, bronchitis, and
emphysema; symptomatic relief of rhinorrhea associated with the common cold and allergic and
nonallergic rhinitis

Azithromycine (Zithromax) tab 250 mg susp 100,250mg/5cc children2 y-old 12mg/kg/daily

Bacterial sinusitis: Oral: Children 6 months: 10 mg/kg once daily for 3 days
(maximum: 500 mg/day)

Pharyngitis, tonsillitis: Oral: Children 2 years: 12 mg/kg/day once daily for

5 days (maximum: 500 mg/day)

Cardiac glycosides: Macrolides may increase the serum concentrations of

cardiac glycosides; monitor.

Warfarin: Azithromycin and other macrolides may decrease metabolism, via

CYP isoenzymes, of warfarin. Monitor for increased effects.

Belladonna Pb Atropine+Hyosine+Hyocyamine+Phenobarbital 0.1 cc/kg

Bisacodyl ped Supp 5mg-----------1 +adult supp 10 mg------------------1-2

DOSING: PEDIATRIC

Relief of constipation:

Oral: Children >6 years: 5-10 mg (0.3 mg/kg) at bedtime or before breakfast

Rectal (suppository): Children:

<2 years: 5 mg as a single dose

>2 years: 10 mg

Bromhexine hcl elixir Mucolytic Agent syr 5cc=4mg

 Oral:

Children <2 years: 1 mg 3 times/day

Children 2-6 years: 4 mg(5cc) twice daily or 2 mg 3 times/day

Children 6-12 years: 4 mg(5cc) 3 times/day

Children >12 years and Adults: 8 mg(10cc) 3 times/day

Cefixime

tab 200&400 mg susp 100mg/5cc---------------8mg/kg/daily---bd-------------- 0.5cc/kg/daily---bd

USE Treatment of urinary tract infections, otitis media, respiratory infections due to susceptible
organisms including S. pneumoniae and S. pyogenes, H. influenzae and many Enterobacteriaceae;
uncomplicated cervical/urethral gonorrhea due to N. gonorrhoeae

DOSING: ADULTS

Susceptible infections: Oral: 400 mg/day divided every 12-24 hours

Uncomplicated cervical/urethral gonorrhea due to N. gonorrhoeae: Oral: 400 mg as a single dose

Note: For S. pyogenes infections, treat for 10 days

DOSING: PEDIATRIC

Susceptible infections: Oral:

Children 6 months: 8 mg/kg/day divided every 12-24 hours

Children >50 kg or >12 years: Refer to adult dosing.

Note: For S. pyogenes infections, treat for 10 days

Cotrimoxasole Susp 40 mgTMP=5cc pediatric tab=20 mgTMP/Adult tab=80mgTMP

8-10 mg/kg/24hrs TMP 10 kg= 5cc BD

Shigellosis:

Oral: 8 mg TMP/kg/day in divided doses every 12 hours for 5 days

I.V.: 8-10 mg TMP/kg/day in divided doses every 6, 8, or 12 hours for up to 5 days

Acute otitis media:

Oral: 8 mg TMP/kg/day in divided doses every 12 hours for 10 days

Urinary tract infection:

 Treatment:

Oral: 6-12 mg TMP/kg/day in divided doses every 12 hours

I.V.: 8-10 mg TMP/kg/day in divided doses every 6, 8, or 12 hours for up to 4 days with serious
infections

Prophylaxis: Oral: 2 mg TMP/kg/dose daily or 5 mg TMP/kg/dose twice weekly

CONTRAINDICATIONS Hypersensitivity to any sulfa drug, trimethoprim, or any component of the

formulation; porphyria; megaloblastic anemia due to folate deficiency; infants <2 months of age; marked
hepatic damage; severe renal disease; pregnancy (at term)

Diazepam

DOSING: PEDIATRIC

Conscious sedation for procedures:

Oral:

Children: 0.2-0.3 mg/kg (maximum dose: 10 mg) 45-60 minutes prior to procedure

Adolescents: 10 mg

I.V.: Adolescents: 5 mg; may repeat with 2.5 mg if needed

Febrile seizure prophylaxis: Oral: Children: 1 mg/kg/day divided every 8 hours; initiate therapy at first
sign of fever and continue for 24 hours after fever is gone

Sedation or muscle relaxation or anxiety:

Oral: Children: 0.12-0.8 mg/kg/day in divided doses every 6-8 hours

I.M., I.V.: Children: 0.04-0.3 mg/kg/dose every 2-4 hours to a maximum of 0.6 mg/kg within an 8-hour
period if needed
Status epilepticus:

I.V.:

Infants >30 days and Children <5 years: 0.05-0.3 mg/kg/dose given over 3-5 minutes, every 15-30
minutes to a maximum total dose of 5 mg or 0.2-0.5 mg/dose every 2-5 minutes to a maximum total dose
of 5 mg; repeat in 2-4 hours as needed

Children 5 years: 0.05-0.3 mg/kg/dose given over 3-5 minutes, every 15-30 minutes to a maximum
total dose of 10 mg or 1 mg/dose every 2-5 minutes to a maximum of 10 mg; repeat in 2-4 hours as needed

Rectal: 0.5 mg/kg/dose then 0.25 mg/kg/dose in 10 minutes if needed

Anticonvulsant (acute treatment): Rectal gel:

Infants <6 months: Not recommended

Children <2 years: Safety and efficacy have not been studied

Children 2-5 years: 0.5 mg/kg

Children 6-11 years: 0.3 mg/kg

Children 12 years: Refer to adult dosing.

Note: Dosage should be rounded upward to the next available dose, 2.5, 5, 10, 12.5, 15, 17.5, and 20
mg/dose; dose may be repeated in 4-12 hours if needed; do not use for more than 5 episodes per month or
more than one episode every 5 days.

Muscle spasm associated with tetanus: I.V., I.M.:

Infants >30 days: 1-2 mg/dose every 3-4 hours as needed

Children 5 years: 5-10 mg/dose every 3-4 hours as needed

In children, do not exceed 1-2 mg/minute IVP; adults 5 mg/minute

Diphenhydramine HCL Elixir 12.5mg=5cc tab 25 mg

5mg/kg/24hrs

10 kg =5cc tds-qid

DOSING: PEDIATRIC

Treatment of dystonic reactions and moderate to severe allergic reactions: Oral, I.M., I.V.: 5 mg/kg/day
or 150 mg/m2/day in divided doses every 6-8 hours, not to exceed 300 mg/day
Minor allergic rhinitis or motion sickness: Oral, I.M., I.V.:

2 to <6 years: 6.25 mg every 4-6 hours; maximum: 37.5 mg/day

6 to <12 years: 12.5-25 mg every 4-6 hours; maximum: 150 mg/day

12 years: 25-50 mg every 4-6 hours; maximum: 300 mg/day

Night-time sleep aid: 30 minutes before bedtime: Oral, I.M., I.V.:

2 to <12 years: 1 mg/kg/dose; maximum: 50 mg/dose

12 years: 50 mg

Antitussive: Oral, I.M., I.V.:

2 to <6 years: 6.25 mg every 4 hours; maximum 37.5 mg/day

6 to <12 years: 12.5 mg every 4 hours; maximum 75 mg/day

12 years: 25 mg every 4 hours; maximum 150 mg/day

Diphenhydramine compound=Diphenhydramine+Sodium citrate+Ammonium chloride+Menthol

Dexa methasone in Croup 0.6 mg/kg/IM/stat

Dicyclomine Gastrointestinal motility disorders/irritable bowel

Amp 20 mg syr 5cc=10 mg

child=10 mg

DOSING: PEDIATRIC Oral:

Infants >6 months: 5 mg/dose 3-4 times/day

Children: 10 mg/dose 3-4 times/day

Dimethicone(activated simethicone) drop 1cc=40 mg inf max=15 drop tds

Child max 20 drop tds

DOSING: PEDIATRIC Flatulence/bloating: Oral:

Infants: 20 mg 4 times/day

Children <12 years: 40 mg 4 times/day

Children >12 years: Refer to adult dosing.

DOSING: ADULTS Flatulence/bloating: Oral: 40-120 mg after meals and at bedtime as needed, not to
exceed 500 mg/day

Domperidone Motilium

PHARMACOLOGIC CATEGORY

Dopamine Antagonist

Gastrointestinal Agent, Prokinetic

DOSING: ADULTS

GI motility disorders: Oral: 10 mg 3-4 times/day, 15-30 minutes before meals

Severe/resistant cases: 20 mg 3-4 times/day, 15-30 minutes before meals

Nausea/vomiting associated with dopamine-agonist anti-Parkinson agents: Oral: 20 mg 3-4 times/day

Erythromycine susp 200 mg=5cc tab 200 & 400 mg 30-50 mg /kg/24 hrs------ qid

DOSING: ADULTS

Usual dosage range:

Oral: (Note: Due to differences in absorption, 400 mg erythromycin ethylsuccinate produces the same
serum levels as 250 mg erythromycin base, sterate or estolate)

Base: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

Estolate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

Ethylsuccinate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 3.2 g/day

Stearate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

I.V.: Lactobionate: 15-20 mg/kg/day divided every 6 hours or 500 mg to 1 g every 6 hours, or given as a
continuous infusion over 24 hours (maximum: 4 g/24 hours)

Ophthalmic infection: Ophthalmic: Instill 1/2" (1.25 cm) 2-6 times/day depending on the severity of the
infection
Dermatologic infection: Topical: Apply over the affected area twice daily after the skin has been
thoroughly washed and patted dry

Indication-specific dosing:

Cervicitis: Oral: 500 mg 4 times/day for 7 days

Chancroid (unlabeled use; not a preferred agent): Oral: 500 mg 4 times/day for 7 days

Community-acquired pneumonia, bronchitis: Oral, I.V.: 500-1000 mg 4 times/day for 10-14 days. If
Legionella is suspected/confirmed, 750-1000 mg 4 times/day for 21 days or more may be recommended.
Note: Other macrolides and/or fluoroquinolones may be preferred and better tolerated.

Lymphogranuloma venereum: Oral: 500 mg 4 times/day for 21 days

Nongonococcal urethritis (recurrent): Oral: CDC Guidelines for the Treatment of Sexually Transmitted
Diseases recommendation: Metronidazole (2 g as a single dose) plus 7 days of erythromycin base (500 mg
4 times/day) or erythromycin ethylsuccinate (800 mg 4 times/day)

Pertussis: Oral: 250-500 mg every 6 hour; standard treatment course is 14 days, but there is evidence to
support a shorter (7-day) course

Preop bowel preparation (unlabeled use): Oral: 1 g erythromycin base at 1, 2, and 11 PM on the day
before surgery combined with mechanical cleansing of the large intestine and oral neomycin

Gastrointestinal prokinetic (unlabeled use): Oral: Erythromycin has been used as a prokinetic agent to
improve gastric emptying time and intestinal motility. In adults, 200 mg was infused I.V. initially followed
by 250 mg orally 3 times/day 30 minutes before meals. Lower dosages have been used in some trials.

DOSING: PEDIATRIC

Prophylaxis of neonatal gonococcal or chlamydial conjunctivitis: Neonates: Ophthalmic: 0.5-1 cm ribbon

of ointment should be instilled into each conjunctival sac

Usual dosage range: Infants and Children:

Oral:Note: Due to differences in absorption, 400 mg erythromycin ethylsuccinate produces the same
serum levels as 250 mg erythromycin base, stearate or estolate).

Base: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

Estolate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

Ethylsuccinate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 3.2 g/day

Stearate: 30-50 mg/kg/day in 2-4 divided doses; do not exceed 2 g/day

I.V. (as lactobionate): 15-50 mg/kg/day divided every 6 hours, not to exceed 4 g/day
Indication-specific dosing:

Acne vulgaris (unlabeled use): Adolescents: Oral: 250-1500 mg/day in 2 divided doses; therapy may be
continued for 4-6 weeks at lowest possible dose

Pharyngitis: Oral: 40 mg/kg/day in 2 doses; maximum: 1600 mg/day; short-course therapy for 5 days
may be considered

Pertussis: Oral: 40-50 mg/kg/day in divided doses; standard treatment course is 14 days, but there is
evidence to support a shorter (7-day) course

Preop bowel preparation: Oral: 20 mg/kg erythromycin base at 1, 2, and 11 PM on the day before
surgery combined with mechanical cleansing of the large intestine and oral neomycin

Ophthalmic infection: Ophthalmic: Refer to adult dosing.

Topical: Refer to adult dosing.

Guaifenesine(Expectorant ) syr 100 mg =5cc

Cough (expectorant): Oral: Children:

6 months to 2 years: 25-50 mg every 4 hours, not to exceed 300 mg/day

2-5 years: 50-100 mg every 4 hours, not to exceed 600 mg/day

6-11 years: 100-200 mg every 4 hours, not to exceed 1.2 g/day

>12 years: Refer to adult dosing.

WARNINGS / PRECAUTIONS Not for persistent cough such as

occurs with smoking, asthma, chronic bronchitis, or emphysema or cough
accompanied by excessive secretions. When used for self-medication (OTC),
contact healthcare provider if needed for >7 days or for a cough with a
fever, rash, or persistent headache.

Ferrous sulfate

DOSING: ADULTS Dose expressed in terms of ferrous sulfate:

Treatment of iron deficiency anemia: Oral: 300 mg twice daily up to 300 mg 4 times/day or 250 mg
(extended release) 1-2 times/day

Prophylaxis of iron deficiency: Oral: 300 mg/day

DOSING: PEDIATRIC Dosage expressed in terms of elemental iron:

Treatment of severe iron-deficiency anemia: Oral: 4-6 mg Fe/kg/day in 3 divided doses

Treatment of mild-to-moderate iron-deficiency anemia: Oral: 3 mg Fe/kg/day in 1-2 divided doses

Prophylaxis: Oral: 1-2 mg Fe/kg/day up to a maximum of 15 mg/day

ADMINISTRATION Administer ferrous sulfate 2 hours prior to, or 4 hours after antacids

ADVERSE REACTIONS SIGNIFICANT

>10%: Gastrointestinal: GI irritation, epigastric pain, nausea, dark stools, vomiting, stomach cramping,
constipation

1% to 10%:

Gastrointestinal: Heartburn, diarrhea

Genitourinary: Discoloration of urine

Miscellaneous: Liquid preparations may temporarily stain the teeth

<1% (Limited to important or life-threatening): Contact irritation

CONTRAINDICATIONS Hypersensitivity to iron salts or any component of the formulation;

hemochromatosis, hemolytic anemia

Furazolidone susp 50mg=15cc tab 100 mg max 8mg/kg/24hrs

DOSING: PEDIATRIC Diarrhea/enteritis: Oral: Children >1 month: 5-8

mg/kg/day in 4 divided doses for 7 days, not to exceed 400 mg/day or 8.8
mg/kg/day

ADVERSE REACTIONS SIGNIFICANT

>10%: Genitourinary: Discoloration of urine (dark yellow to brown)

1% to 10%:

Central nervous system: Headache

Gastrointestinal: Abdominal pain, diarrhea, nausea, vomiting

 <1% (Limited to important or life-threatening): Agranulocytosis, disulfiram-
like reaction after ethanol ingestion, hemolysis in patients with G6PD
deficiency, hypoglycemia, leukopenia, orthostatic hypotension

CONTRAINDICATIONS Hypersensitivity to furazolidone or any

component of the formulation; concurrent use of ethanol; infants <1 month
of age because of the possibility of producing hemolytic anemia; foods high
in tyramine content

WARNINGS / PRECAUTIONS Use caution in patients with G6PD

deficiency when administering large doses for prolonged periods;
furazolidone inhibits monoamine oxidase

Hydroxyzine syr 10 mg=5cc tab 10,25 mg amp 100 mg=2cc

2mg/kg/24hrs 10kg=2.5cc tds-qid

Metronidasole susp 125 mg=5cc tab 250mg

Amebiasis 35-50 mg/kg/24hrs 10kg=5cc

Giardiasis 15 mg/kg/24hrs 10 kg=2cc

Multivitamine Syr 5cc daily Drop 0.6 cc daily

MOM (mg(oh)2) 0.5-1 cc/kg +200cc water

Metoclopramide drop 60mg=15cc amp 10mg=2cc

1cc=15 drop=4mg

0.1 mg/kg/dose 5kg=2drop qid

Nystatine term more than 2500gr = 30drops tab500000 iu

Less than 2500 gr = 15 drops

Children 400000-600000 iu or tab/qid

Mebandasole chewable tab 100 mg

Promethasine syr 5.65 mg=5cc tab 25mg amp 25,50 mg

 1mg/kg/24hrs 10kg=2.5cc

Phenobarbital tab 15,30,60,100 amp 100, 200 mg

Amp 10 mg/kg/IM/stat amp 5mg/kg/24hrs/bd/Im

Phenytoine amp 15/mg/kg/stat slowly IV 4-8 mg/kg24hrs/bd

Pyrantel pamoate tab 125 mg syr 250mg=5cc

11mg/kg/dose single dose 20kg=5cc

Salbutamole (ventoline) syr 2mg=5cc 0.15 mg/kg/dose

0.375cc/kg